Preoperative Evaluation and Risk Assessment for Elderly Thoracic Surgery Patients

Thoracic Surgery Clinics

Volumn 19, Issue 3, 2009, Pages 301-312

  Jaklitsch, Michael ^a   Billmeier, Sarah ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Elderly; Geriatric assessment; Lung cancer; Preoperative assessment; Thoracic surgery

Indexed keywords

CARDIOVASCULAR RISK; COMORBIDITY; ESOPHAGUS CANCER; GERIATRIC CARE; HUMAN; LUNG CANCER; MORTALITY; PATIENT SAFETY; PATIENT SELECTION; PERIOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; THORACOTOMY; THORAX SURGERY;

AGE FACTORS; AGED; HUMANS; PREOPERATIVE CARE; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; THORACIC DISEASES; THORACIC SURGICAL PROCEDURES;

EID: 70449120247     PISSN: 15474127     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thorsurg.2009.07.004     Document Type: Review

References (87)

1. Kung H.C., Hoyery D.L., and Xu J. Deaths: final data for 2005. Centers for Disease Control. Natl Vital Stat Rep 56 10 (2008) 1-120
2. US Census Bureau, population division. Table 2. Projections of the population by selected age groups and sex for the United States: 2010 to 2050 (NP2008-T2). Release date August 14, 2008. Available at: http://www.census.gov/population/www/projections/files/nation/summary/np 2008-t2.xls. Accessed September 2, 2009.
3. US Census Bureau, population division. Table 3. Percent distribution of the projected population by selected age groups and sex for the United States: 2010 to 2050 (NP2008-T3). Release date August 14, 2008. Available at: http://www.census.gov/population/www/projections/files/nation/summary/np 2008-t3.xls. Accessed September 2, 2009.
4. American Cancer Society. Cancer facts & figures: age-adjusted cancer death rates, males by site. Available at: (2008). http://www.cancer.org/docroot/MED/content/MED_1_1_Most_Requested_Graphs_ and_Figures_2008.asp Accessed September 2, 2009
5. American Cancer Society. Cancer facts & figures: age-adjusted cancer death rates, females by site. Available at: (2008). http://www.cancer.org/docroot/MED/content/MED_1_1_Most_Requested_Graphs_ and_Figures_2008.asp Accessed September 2, 2009
6. Ries L., Melbert D., Krapcho M., et al. SEER cancer statistics review, 1975-2005. Bethesda (MD): National Cancer Institute. Available at:. http://seer.cancer.gov/csr/1975_2005 Based on November 2007 SEER data submission posted to the SEER Web site, 2008. Accessed September 2, 2009
7. O'Rourke M.A., Feussner J.R., Feigl P., et al. Age trends of lung cancer stage at diagnosis: implications for lung cancer screening in the elderly. JAMA 258 (1987) 921-926
8. Mery C.M., Pappas A.N., Bueno R., et al. Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the Surveillance, Epidemiology, and End Results database. Chest 128 (2005) 237-245
9. Teeter S.M., Holmes F.F., and McFarlane M.J. Lung carcinoma in the elderly population: influence of histology on the inverse relationship of stage to age. Cancer 60 (1987) 1331-1336
10. Weinmann M., Jeremie B., Toomes H., et al. Treatment of lung cancer in the elderly. Part I. Non-small cell lung cancer. Lung Cancer 39 (2003) 233-253
11. Morandi U., Stefani A., Golinelli M., et al. Results of surgical resection in patients over the age of 70 years with non-small cell lung cancer. Eur J Cardiothorac Surg 11 (1997) 432-449
12. Gail M.H., Eagan R.T., Feld R., et al. Prognostic factors in patients with resected stage I non-small cell lung cancer: a report from the Lung Cancer Study Group. Cancer 54 (1984) 1802-1813
13. Mountain C.F., Lukeman J.M., Hammar S.P., et al. Lung cancer classification: the relationship of disease extent and cell type to survival in a clinical trials population. J Surg Oncol 35 (1987) 147-156
14. Deslauriers J., and Gregoire J. Surgical therapy of early non-small cell lung cancer. Chest 117 Suppl (2000) 104S-109S
15. Faulkner S.L. Is lobectomy the gold standard for stage I lung cancer in year 2000? [abstract]. Chest 118 Suppl 4 (2000) 119S
16. Bates M. Results of surgery for bronchial carcinoma in patients aged 70 and over. Thorax 25 (1970) 77-78
17. Evans E.W. Resection of bronchial carcinoma in the elderly. Thorax 28 (1973) 86-88
18. Kirsh M.M., Rotman H., Bove E., et al. Major pulmonary resection for bronchial carcinoma in the elderly. Ann Thorac Surg 22 (1976) 369-373
19. Harviel J.D., McNamara J.J., and Straehley C.J. Surgical treatment of lung cancer in patients over the age of 70 years. J Thorac Cardiovasc Surg 75 (1978) 802-805
20. Ginsberg R.J., Hill L.D., Eagan R.T., et al. Modern thirty-day operative mortality for surgical resections in lung cancer. J Thorac Cardiovasc Surg 86 (1983) 654-658
21. Mery C.M., and Jaklitch M.T. Lung resection in the elderly, correspondence. Chest 129 (2006) 496-497
22. Albano W.A. Should elderly patients undergo surgery for cancer. Geriatrics 32 (1977) 105-108
23. Breyer R.H., Zippe C., Pharr W.F., et al. Thoracotomy in patients over age seventy years: ten-year experience. J Thorac Cardiovasc Surg 81 (1981) 187-193
24. Zapatero J., Madrigal L., Lago J., et al. Thoracic surgery in the elderly: review of 100 cases. Acta Chir Hung 31 (1990) 227-234
25. Allen M.S., Darling G.E., Pechet T.T., et al. ACOSOG Z0030 Study Group. Morbidity and mortality of major pulmonary resections in patients with early stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg 81 3 (2006) 1013-1019
26. Decamp Jr. M.M., Jaklitsch M.T., Mentzer S.J., et al. The safety and versatility of video-thoracoscopy: a prospective analysis of 895 cases. J Am Coll Surg 181 (1995) 113-120
27. McKenna R. Thoracoscopic lobectomy with mediastinal sampling in 80 year old patients. Chest 106 (1994) 1902-1904
28. Landreneau R.L., Sugarbaker D.J., Mack M.J., et al. Postoperative pain-related morbidity: video-assisted thoracic surgery versus thoracotomy. Ann Thorac Surg 56 (1993) 1285-1289
29. Jaklitsch M.T., Bueno R., Swanson S.J., et al. Video-assisted thoracic surgery in the elderly: a review of 307 cases. Chest 110 (1996) 751-758
30. Cattaneo S.M., Park B.J., Wilton A.S., et al. Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications. Ann Thorac Surg 85 (2008) 231-236
31. Samet J., Hunt W.C., Key C., et al. Choice of cancer therapy varies with age of patient. JAMA 255 (1986) 3385-3390
32. Gridelli C., Langer C., Maione P., et al. Lung cancer in the elderly. J Clin Oncol 25 14 (2007) 1899-1907
33. McGarry R.C., Song G., des Rosiers P., et al. Observation-only management of early stage, medically inoperable lung cancer: poor outcome. Chest 121 (2002) 1155-1158
34. Yellin A., and Brenfield J.R. Surgery for bronchogenic carcinoma in the elderly. Am Rev Respir Dis 131 (1985) 197
35. Arias E. United States life tables, 2004. Natl Vital Stat Rep 56 9 (2007) 1-39
36. Kelsen D.P., Bains M., and Burt M. Neoadjuvant chemotherapy and surgery of cancer of the esophagus. Semin Surg Oncol 6 5 (1990) 268-273
37. Ferguson M.K., Martin T.R., Reeder L.B., et al. Mortality after esophagectomy: risk factor analysis. World J Surg 23 (1997) 599-604
38. Adam D.J., Craig S.R., Sang C.T., et al. Esophagectomy for carcinoma in the octogenarian. Ann Thorac Surg 61 (1996) 190-194
39. Suglmachi K., Matsuzaki K., Matsuura H., et al. Evaluation of surgical treatment of carcinoma of the oesophagus in the elderly: 20 years experience. Br J Surg 72 (1985) 28-32
40. Poon R.T., Law S.Y., Chu K.M., et al. Esophagectomy for carcinoma of the esophagus in the elderly: results of current surgical management. Ann Surg 227 3 (1998) 357-364
41. Kinugasa S., Tachibana M., Yoshimura H., et al. Esophageal resection in elderly esophageal carcinoma patients: improvement in postoperative complications. Ann Thorac Surg 71 (2001) 414-418
42. Thomas P., Doddoli C., Neville P., et al. Esophageal cancer resection in the elderly. Eur J Cardiothorac Surg 10 (1996) 941-946
43. Ellis Jr. F.H., Williamson W.A., and Heatley G.J. Cancer of the esophagus and cardia: does age influence treatment selection and surgical outcomes. J Am Coll Surg 187 4 (1998) 345-351
44. Rossi A., Ganassini A., Tantucci C., et al. Aging and the respiratory system. Aging (Milano) 8 3 (1996) 143-161
45. Janssens J.P., Pache J.C., and Nicod L.P. Physiological changes in respiratory function associated with ageing. Eur Respir J 13 (1999) 197-205
46. Meyer K.C. Lung infections and aging. Ageing Res Rev 3 1 (2004) 55-67
47. Verra F., Escudier E., Lebargy F., et al. Ciliary abnormalities in bronchial epithelium of smokers, ex-smokers, and nonsmokers. Am J Respir Crit Care Med 151 3 (1995) 630-634
48. Salathe M., O'Riordan T.G., and Wanner A. Treatment of mucociliary dysfunction. Chest 110 (1996) 1048-1057
49. McLesky C.H. Anesthesia for the geriatric patient. In: Barash P.G., Cullen B.F., and Staelting R.K. (Eds). Clinical anesthesia. 2nd edition (1992), JB Lippincott, Philadelphia 1353-1383
50. Eagle K.A., Berger P.B., Calkins H., et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery. Circulation 105 (2002) 1257-1267
51. Auerbach A., and Goldman L. Assessing and reducing the cardiac risk of noncardiac surgery. Circulation 113 (2006) 1361-1376
52. Lee T.H., Marcantonio M.D., Mangione C.M., et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation 100 (1999) 1043-1049
53. Passman R.S., Gingold D.S., Amar D., et al. Prediction rule for atrial fibrillation after major noncardiac thoracic surgery. Ann Thorac Surg 79 (2005) 1698-1703
54. Roselli E.E., Murthy S.C., Rice T.W., et al. Atrial fibrillation complicating lung cancer resection. J Thorac Cardiovasc Surg 130 (2005) 438-444
55. Sedrakyan A., Treasure T., Browne J., et al. Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials. J Thorac Cardiovasc Surg 129 (2005) 997-1005
56. British Thoracic Society, Society of Cardiothoracic Surgeons of Great Britain and Ireland Working Party. Guidelines on the selection of patients with lung cancer for surgery. Thorax 56 (2001) 89-108
57. Colice G.L., Shafazand S., Griffin J.P., et al. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: ACCP evidence-based clinical practice guidelines [2nd edition]. Chest 132 (2007) 161-177
58. Wyser C., Stulz P., Soler M., et al. Prospective evaluation of an algorithm for the functional assessment of lung resection candidates. Am J Respir Crit Care Med 159 (1999) 1450-1456
59. Datta D., and Lahiri B. Preoperative evaluation of patients undergoing lung resection surgery. Chest 123 (2003) 2096-2103
60. Linden P.A., Bueno R., Colson Y.L., et al. Lung resection in patients with preoperative FEV1 <35% predicted. Chest 127 (2005) 1984-1990
61. Ferguson M.K., Little L., Rizzo L., et al. Diffusing capacity predicts morbidity and mortality after pulmonary resection. J Thorac Cardiovasc Surg 96 (1988) 894-900
62. Stephan F., Boucheseiche S., Hollande J., et al. Pulmonary complications following lung resection: a comprehensive analysis of incidence and possible risk factors. Chest 118 (2000) 1263-1270
63. Botsen P.C., Block A.J., and Moulder P.C. Relationship between preoperative pulmonary function tests and complications after thoracotomy. Surg Gynecol Obstet 52 (1981) 813-815
64. Girish M., Trayner E., Dammann O., et al. Symptom-limited stair climbing as a predictor of postoperative cardiopulmonary complications after high risk surgery. Chest 120 (2001) 1147-1151
65. Solway S., Brooks D., Lacasses Y., et al. A qualitative systematic overview of the measurement properties of functional walk tests used in the cardiorespiratory domain. Chest 119 1 (2001) 256-270
66. Jaklitsch M.T., Mery C.M., and Audisio R.A. The use of surgery to treat lung cancer in elderly patients. Lancet Oncol 4 (2003) 463-471
67. Olsen G.N., Block A.J., and Tobias J.A. Prediction of postpnemonectomy pulmonary function using quantitative macroaggregate lung scanning. Chest 66 (1974) 13-16
68. Pate P., Tenholder M.F., Griffin J.P., et al. Preoperative assessment of the high-risk patient for lung resection. Ann Thorac Surg 61 (1996) 1494-1500
69. Markos J., Mullan B.P., Hillman D.R., et al. Preoperative assessment as a predictor of mortality and morbidity after lung resection. Am Rev Respir Dis 139 (1989) 902-910
70. Bolliger C.T., Wyser C., Boser H., et al. Lung scanning and exercise testing for the prediction of postoperative performance in lung resection candidates at increased risk of complications. Chest 108 (1995) 341-348
71. Holden D.A., Rice T.W., Stefmach K., et al. Exercise testing, 6-min walk, and stair climb in the evaluation of patients at high risk for pulmonary resection. Chest 102 (1992) 1774-1779
72. Wahi R., McMurtry M.J., DeCaro L.F., et al. Determinants of perioperative morbidity and mortality after pneumonectomy. Ann Thorac Surg 48 (1989) 33-37
73. Brock M.V., Kim M.P., Hooker C.M., et al. Pulmonary resection in octogenarians with stage I non-small cell lung cancer: a 22-year experience. Ann Thorac Surg 77 (2004) 271-277
74. Moller J.T., Cluitmans P., Rasmussen L.S., et al. Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study. Lancet 351 (1998) 857-861
75. Rasmussen L.S., Siersma V.D., and ISPOCD Group. Postoperative cognitive dysfunction: true deterioration versus random variation. Acta Anaesthesiol Scand 48 (2004) 1137-1143
76. Newman S., Stygall J., Shaefi S., et al. Postoperative cognitive dysfunction after noncardiac surgery. Anesthesiology 106 (2007) 572-590
77. Kaneko T., Takahashi S., Naka T., et al. Postoperative delirium following gastrointestinal surgery in elderly patients. Surg Today 27 (1997) 107-111
78. Fukuse T., Satoda N., Hijiya K., et al. Importance of a comprehensive geriatric assessment in prediction of complications following thoracic surgery in elderly patients. Chest 127 (2005) 886-891
79. Audisio R.A., Ramesh H., Longo W., et al. Preoperative assessment of surgical risk in oncogeriatric patients. Oncologist 10 (2005) 262-268
80. Narian O., Rubenstein L., Wieland B., et al. Predictors of immediate and 6 month outcomes in hospitalized elderly patients: the importance of functional status. J Am Geriatr Soc 36 (1988) 775-783
81. Reuben D., Rubenstein L., Hirsch S.H., et al. Value of functional status as a predictor of mortality: results of a prospective study. Am J Med 93 6 (1992) 663-669
82. Landi F., Zaccala G., Gambassi G., et al. Body mass index and mortality among older people living in the community. J Am Geriatr Soc 47 (1999) 1072
83. Buccheri G., Ferrigno D., and Tamburini M. Karnofsky and ECOG performance status scoring in lung cancer: a prospective, longitudinal study of 536 patients from a single institution. Eur J Cancer 32 7 (1996) 1135-1141
84. Harpole Jr. D.H., Herndon II J.F., Young Jr. W.G., et al. Stage I non-small cell lung cancer: a multivariate analysis of treatment methods and patterns of recurrence. Cancer 76 (1995) 787-796
85. Stamatis G., Djuric D., Eberhardt W., et al. Postoperative morbidity and mortality after induction chemoradiotherapy for locally advanced lung cancer: an analysis of 350 operated patients. Eur J Cardiothorac Surg 22 (2002) 292-297
86. Ferguson M.K., and Vigneswaran W.T. Diffusing capacity predicts morbidity after lung resection in patients without obstructive lung disease. Ann Thorac Surg 85 4 (2008) 1158-1164
87. Jaklitsch MT, Battafarano R, Hurria A. CALGB protocol proposal: a study to compare surgical choice and recovery as predicted by a brief geriatric assessment for patients 70 years of age and older undergoing surgical resection for lung nodules. Unpublished study protocol, used with permission.