99mTc-Tricarbonyl Complexes Functionalized with Anthracenyl Fragments: Synthesis, Characterization, and Evaluation of Their Radiotoxic Effects in Murine Melanoma Cells

Cancer Biotherapy and Radiopharmaceuticals

Volumn 24, Issue 5, 2009, Pages 551-563

  Vitor, Rute F ^a   Esteves, Teresa ^a   Marques, Fernanda ^a   Raposinho, Paula ^a   Paulo, António ^a   Rodrigues, Sebastião ^b   Rueff, José ^b   Casimiro, Sandra ^c   Costa, Luís ^c   Santos, Isabel ^a  

^a INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^c INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

Anthracene derivatives; Auger electrons; Nuclear targeting; Radiotoxicity; Technetium 99m

Indexed keywords

ANTHRACENYL; DIAMINE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M; TECHNETIUM TRICARBONYL TC 99M; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUGER ELECTRON SPECTROSCOPY; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTHRACENES; APOPTOSIS; CELL NUCLEUS; CHELATING AGENTS; DNA; ELECTRONS; LIGANDS; MELANOMA, EXPERIMENTAL; MICE; MODELS, CHEMICAL; PROTEIN BINDING; RADIOPHARMACEUTICALS; TECHNETIUM;

EID: 70449113426     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2009.0647     Document Type: Article

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