Targeted sustained delivery of tobramycin at the site of a femoral osteotomy

Biomedical Sciences Instrumentation

Volumn 42, Issue , 2006, Pages 530-535

  Benghuzzi, Hamed ^a   Tucci, Michelle ^a   Russell, George ^a   Ragab, Ashraf ^a   Graves, Matt ^a   Conflitti, Joseph ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Antibiotics; Drug Delivery; Osteoconduction; Sustained Release; TCPL; Tobramycin

Indexed keywords

ANTIBIOTICS; BIOLOGICAL ORGANS; DISEASES; DRUG THERAPY; ENZYME KINETICS; RISK ASSESSMENT; SURGERY; SURGICAL EQUIPMENT; AMINO ACIDS; ANIMALS; CERAMIC MATERIALS; CONCENTRATION (PROCESS); DRUG DELIVERY; INSTRUMENTS; LANDFORMS;

DRUG DELIVERY; OSTEOCONDUCTION; SUSTAINED RELEASE; TCPL; TOBRAMYCIN;

PATIENT MONITORING; ANTIBIOTICS;

ALKALINE PHOSPHATASE; ANTIBIOTIC AGENT; CALCIUM PHOSPHATE; TOBRAMYCIN; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; BODY WEIGHT; BONE CONDUCTION; CERAMICS; CONFERENCE PAPER; CONTROLLED STUDY; DEBRIDEMENT; DRUG CAPSULE; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; FEMUR OSTEOTOMY; FRACTURE; FRACTURE FIXATION; GENITAL SYSTEM; INFECTION RISK; MALE; NONHUMAN; RAT; SUPERINFECTION; SURGICAL TECHNIQUE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BONE SUBSTITUTES; DRUG IMPLANTS; FEMORAL FRACTURES; FEMUR; MALE; OSTEITIS; OSTEOTOMY; RATS; TOBRAMYCIN; TREATMENT OUTCOME;

ALKALINE PHOSPHATASE ACTIVITY; ANIMAL MODEL; ANTIBIOTIC THERAPY; BIORESORBABLE; CONCENTRATION OF; DELIVERY VEHICLE; ON-BODY; OSTEOCONDUCTION; OSTEOCONDUCTIVE; OSTEOCONDUCTIVE MATERIALS; REPRODUCTIVE ORGANS; SIDE EFFECT; SURGICAL PROCEDURES; SUSTAINED RELEASE; TCPL; TOBRAMYCIN; TRI-CALCIUM PHOSPHATES;

EID: 70449098969     PISSN: 00678856     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (17)

1. Border J. R., Bone LB, Babikian, and Rodriguez. A History of the Care of Trauma. In: Blunt Multiple Trauma; Comprehensive pathophysiology and care. Editor: John Border. Marcel Dekker, INC, 1990 pp 6-7.
2. Keating JF, Blachut PA, O'Brien PJ, Meek RN, Broekhuyse H. J Orthop Trauma. 1996;10(5):298-303.
3. Van de Belt H, Neut D, Van Horn J.R., Van der Mei HC, Schenk W and Busscher HJ. Nature Medicine 1999;5:358-359
4. Shirtliff ME, Calhoun JH, Mader JT. Clin Orthop 2002 Aug; 2002; (401):239-247.
5. Freiss W, Schlapp M. Pharm Dey Technol 2002 May; 7(2):235-248.
6. Benghuzzi H. and Barry England. Biomed Sci Instrum. 2001; 37: 275-280.
7. Benghuzzi, HA and Bajpai, PK. Journal of Investigative Surgery. 1988;1:63-170.
8. Benghuzzi, HA, England, BG and Bajpai, PK. Journal of Bioactive and Compatible Polymers 1991;6:115-128.
9. Benghuzzi, HA, England, BG, Bajpai, PK. and Giffin, BF. Journal of Clinical Materials. 1994;15:151-160.
10. Cox M Trussell B, Ward J, Tucci M, Benghuzzi H. Biomed Sci Instrum. 2002;38:173-8.
11. Benghuzzi H, Puckett A, Tucci M, Roberts B, Biomed Sci Instrum. 1999;35:321-6.
12. Benghuzzi H. Biomed Sci Instrum. 2000;36:343-8.
13. Butler KR, Benghuzzi HA, Puckett A. Journal of Invest Surg. 2001 (a); May-Jun;14(3):139-52.
14. Butler KR Jr, Benghuzzi HA. Biomed. Sci. Instrum. 2003;39:541-6.
15. Butler KR, Benghuzzi HA, Puckett A. Journal of Pathology: Clinical Practice. Pathol Res Pract. 2001(b); 197(1):29-39.
16. Schopper C, Ziya-Ghazvini F, Goriwoda W, Moser D, Wanschitz F, Spassova E, Lagogiannis G, Autherith A, Ewers R. J Biomed Mater Res B Appl. Biomater. 2005 Jul; 74(1):458-67.
17. McAndrew MP, Pontarelli W. Clin Orthop Relat Res: Jul (232):190-196.