Anastral spindle assembly: A mathematical model

Biophysical Journal

Volumn 97, Issue 8, 2009, Pages 2191-2201

  Hallen, Mark A ^a   Endow, Sharyn A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL AGGREGATION; CELL ELONGATION; CELL FUNCTION; CELL TRANSPORT; CROSS LINKING; MATHEMATICAL MODEL; MITOSIS SPINDLE;

EID: 70449090333     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.08.008     Document Type: Article

References (22)

1. Heald, R., R. Tournebize, T. Blank, R. Sandalzopoulos, P. Becker, et al. 1996. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature. 382:420-425.
2. Matthies, H. J. G., H. B. McDonald, L. S. B. Goldstein, and W. E. Theurkauf. 1996. Anastral meiotic spindle morphogenesis: role of the nonclaret disjunctional kinesin-like protein. J. Cell Biol. 134:455-464.
3. Sköld, H. N., D. J. Komma, and S. A. Endow. 2005. Assembly pathway of the anastral Drosophila meiosis I oocyte spindle. J. Cell Sci. 118:1745-1755.
4. Schuh, M., and J. Ellenberg. 2007. Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes. Cell. 130:484-498. (Pubitemid 47198301)
5. Yang, G., B. R. Houghtaling, J. Gaetz, J. Z. Liu, G. Danuser, et al. 2007. Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging. Nat. Cell Biol. 9:1233-1242.
6. Burbank, K. S., A. C. Groen, Z. E. Perlman, D. S. Fisher, and T. J. Mitchison. 2006. A new method reveals microtubule minus ends throughout the meiotic spindle. J. Cell Biol. 175:369-375.
7. Liang, Z.-Y., M. A. Hallen, and S. A. Endow. 2009. Mature Drosophila meiosis I spindles comprise microtubules of mixed polarity. Curr. Biol. 19:163-168.
8. Nédélec, F. 2002. Computer simulations reveal motor properties generating stable antiparallel microtubule interactions. J. Cell Biol. 158:1005-1015. (Pubitemid 35052684)
9. Schaffner, S. C., and J. V. José. 2006. Biophysical model of self-organized spindle formation patterns without centrosomes and kinetochores. Proc. Natl. Acad. Sci. USA. 103:166-171.
10. Burbank, K. S., T. J. Mitchison, and D. S. Fisher. 2007. Slide-and-cluster models for spindle assembly. Curr. Biol. 17:1373-1383.
11. Lancaster, O. M., C. F. Cullen, and H. Ohkura. 2007. NHK-1 phosphorylates BAF to allow karyosome formation in the Drosophila oocyte nucleus. J. Cell Biol. 179:817-824.
12. Berg, H. C. 1983. Random Walks in Biology. Princeton University Press, Princeton, NJ.
13. Sprague, B. L., R. L. Pego, D. A. Stavreva, and J. G. McNally. 2004. Analysis of binding reactions by fluorescence recovery after photobleaching. Biophys. J. 86:3473-3495. (Pubitemid 38780231)
14. Wachsmuth, M., W. Waldeck, and J. Langowski. 2000. Anomalous diffusion of fluorescent probes inside living cell nuclei investigated by spatially-resolved fluorescence correlation spectroscopy. J. Mol. Biol. 298:677-689.
15. Endow, S. A., and H. Higuchi. 2000. A mutant of the motor protein kinesin that moves in both directions on microtubules. Nature. 406:913-916.
16. Hunt, A. J., F. Gittes, and J. Howard. 1994. The force exerted by a single kinesin molecule against a viscous load. Biophys. J. 67:766-781.
17. Fink, G., L. Hajdo, K. J. Skowronek, C. Reuther, A. A. Kasprzak, et al. 2009. The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding. Nat. Cell Biol. 11:717-723.
18. Zou, J., M. A. Hallen, C. D. Yankel, and S. A. Endow. 2008. A microtubule- destabilizing kinesin motor regulates spindle length and anchoring in oocytes. J. Cell Biol. 180:459-466. (Pubitemid 351240695)
19. Vale, R. D., D. R. Soll, and I. R. Gibbons. 1989. One-dimensional diffusion of microtubules bound to flagellar dynein. Cell. 59:915-925.
20. Chandra, R., S. A. Endow, and E. D. Salmon. 1993. An N-terminal truncation of the ncd motor protein supports diffusional movement of microtubules in motility assays. J. Cell Sci. 104:899-906. (Pubitemid 23123482)
21. Song, H., and S. A. Endow. 1998. Decoupling of nucleotide- and microtubule- binding in a kinesin mutant. Nature. 396:587-590. (Pubitemid 28563721)
22. Hallen, M. A., J. Ho, C. D. Yankel, and S. A. Endow. 2008. Fluorescence recovery kinetic analysis of g-tubulin binding to the mitotic spindle. Biophys. J. 95:3048-3058.