Endothelial dysfunction in patients with kidney failure and vascular risk factors: Acute effects of hemodialysis

Italian Heart Journal

Volumn 5, Issue 5, 2004, Pages 371-377

  Migliacci, Rino ^a   Falcinelli, Francesca ^b   Imperiali, Patrizio ^c   Floridi, Ardesio ^b   Nenci, Giuseppe G ^b   Gresele, Paolo ^b  

^a Civic Hospital   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

Blood flow; Nitric oxide; Vasoconstriction; Vasodilation

Indexed keywords

BIOLOGICAL MARKER; CYCLIC GMP; HOMOCYSTEINE; NITRATE; NITRITE;

ADULT; AGED; ARTICLE; BLOOD; BLOOD FLOW; BLOOD PRESSURE; CHRONIC KIDNEY FAILURE; COMPARATIVE STUDY; DIASTOLE; EVALUATION; FEMALE; HUMAN; KIDNEY; KIDNEY CIRCULATION; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; RENAL REPLACEMENT THERAPY; RISK FACTOR; STATISTICS; SYSTOLE; TIME; TREATMENT OUTCOME; VASCULAR DISEASE; VASCULAR ENDOTHELIUM; VASCULARIZATION; VASODILATATION;

ADULT; AGED; BIOLOGICAL MARKERS; BLOOD PRESSURE; CYCLIC GMP; DIASTOLE; ENDOTHELIUM, VASCULAR; FEMALE; HOMOCYSTEINE; HUMANS; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; NITRATES; NITRITES; REGIONAL BLOOD FLOW; RENAL CIRCULATION; RENAL DIALYSIS; RISK FACTORS; STATISTICS; SYSTOLE; TIME FACTORS; TREATMENT OUTCOME; VASCULAR DISEASES; VASODILATION;

EID: 7044253261     PISSN: 1129471X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Baigent C, Burbury K, Wheeler D. Premature cardiovascular disease in chronic renal failure. Lancet 2000; 356: 147-52.
2. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-25.
3. Cooke PJ, Dzau VJ. Derangements of the nitric oxide synthase pathway, L-arginine, and cardiovascular diseases. Circulation 1997; 96: 379-82.
4. Raitakari OT, Celermajer DS. Flow-mediated dilatation. Br J Clin Pharmacol 2000; 50: 397-404.
5. Celermajer DS, Sorensen KE, Georgakopoulus D, et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilatation in healthy young adults. Circulation 1993; 88: 2249-55.
6. Migliacci R, Gresele P. Smoking and impaired endothelium-dependent dilatation. (letter) N Engl J Med 1996; 334: 1674.
7. John S, Schmieder ES. Impaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences. J Hypertens 2000; 18: 363-74.
8. Jensen-Urstad KJ, Reichard PG, Rosfors JS, Lindblad LE, Jensen-Urstad MT. Early atherosclerosis is retarded by improved long-term blood glucose control in patients with IDDM. Diabetes 1996; 45: 1253-8.
9. Simons LA, Sullivan D, Simons J, Celermajer DS. Effects of atorvastatin monotherapy and simvastatin plus cholestyramine on arterial endothelial function in patients with severe primary hypercholesterolaemia. Atherosclerosis 1998; 137: 197-203.
10. Chambers JC, Obeid OA, Kooner JS. Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subject. Arterioscler Thromb Vasc Biol 1999; 19: 2922-7.
11. Levine GN, Frei B, Koulouris SN, Gerhard MD, Keaney JF, Vita JA. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 1996; 93: 1107-13.
12. Joannides R, Bakkali EL, Le Roy F, et al. Altered flow-dependent vasodilatation of conduit arteries in maintenance haemodialysis. Nephrol Dial Transplant 1997; 12: 2623-8.
13. Kari AJ, Donald AE, Vallance DT, et al. Physiology and biochemistry of endothelial function in children with chronic renal failure. Kidney Int 1997; 52: 468-72.
14. Thambyrajah J, Landray MJ, McGlynn FJ, Jones HJ, Wheeler DC, Townend JN. Abnormalities of endothelial function in patients with predialysis renal failure. Heart 2000; 83: 205-9.
15. Van Guldener C, Lambert J, Janssen MJ, Donker AJ, Stehouwer CD. Endothelium-dependent vasodilatation and distensibility of large arteries in chronic haemodialysis patients. Nephrol Dial Transplant 1997; 12: 14-8.
16. Thambyrajah J, Landray MJ, McGlynn FJ, Jones HJ, Wheeler DC, Townend JN. Does folic acid decrease plasma homocysteine and improve endothelial function in patients with predialysis renal failure? Circulation 2000; 102: 871-5.
17. Rojas A, Romay S, Gonzales D, Herrera B, Delgado R, Otero K. Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end products. Circ Res 2000; 86: E50-E54.
18. Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992; 28: 34-9.
19. Hand MF, Haynes WG, Webb DJ. Hemodialysis and L-arginine, but not D-arginine, correct renal failure-associated endothelial dysfunction. Kidney Int 1998; 53: 1068-77.
20. Cross JM, Donald A, Vallance PJ, Deanfield JE, Woolfson RG, MacAllister RJ. Dialysis improves endothelial function in humans. Nephrol Dial Transplant 2001; 16: 1823-9.
21. Miyazaki H, Matsuoka H, Itabe H, et al. Hemodialysis impairs endothelial function via oxidative stress. Effects of vitamin E-coated dialyzer. Circulation 2000; 101: 1002-6.
22. Cross JM, Donald AE, Kharbanda R, Deanfield JE, Woolfson RG, MacAllister RJ. Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure. Kidney Int 2001; 60: 2318-23.
23. Eikellboom JW, Lonn E, Genest Jr J, Hankey G, Yusuf S. Homocys(e)ine and cardiovascular disease. A critical review of the epidemiologic evidence. Ann Intern Med 1999; 131: 363-75.
24. Schmidt AM, Yan SD, Wautier JL, Stern D. Activation of receptor for advanced glycation end products. A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 1999; 84: 489-97.
25. Stein G, Franke S, Mahiout A, et al. Influence of dialysis modalities on serum AGE levels in end-stage renal disease patients. Nephrol Dial Transplant 2001; 16: 999-1008.
26. Corretti MC, Anderson TJ, Benjamin EJ, et al, for the International Brachial Artery Reactivity Task Force. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. A report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 2002; 39: 257-65.
27. Blum M, Yachnin T, Wollman Y, et al. Low nitric oxide production in patients with chronic renal failure. Nephron 1998; 79: 265-8.
28. Prasad A, Andrews NP, Padder FA, Husain M, Quyyumi AA. Glutathione reverses endothelial dysfunction and improves nitric oxide bioavailability. J Am Coll Cardiol 1999; 34: 507-14.
29. Curtis NE, Gude NM, King RG, Marriot PG, Rook TJ, Brennecke SP. Nitric oxide metabolites in normal human pregnancy and pre-eclampsia. Hypertension in Pregnancy 1995; 14: 339-49.
30. Floridi A, Trizza V, Paolotti P, Lucarelli C. Analytical strategy for the assessment of the protein glycation status in uremic patients by high-performance liquid chromatography. J Chromatogr A 1999; 846: 65-71.
31. Ubbink JB, Vermaak JH, Bissbort S. Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum. J Chromatogr 1991; 565: 441-6.
32. Sorensen KE, Celermajer DS, Spiegelhalter DJ, et al. Noninvasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility. Br Heart J 1995; 74: 247-53.
33. O'Driscoll G, Green D, Maiorana A, Stanton K, Colreavy F, Taylor R. Improvement in endothelial function by angiotensin-converting enzyme inhibition in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 1999; 33: 1506-11.
34. Wever R, Boer P, Hijmering M, et al. Nitric oxide production is reduced in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 1999; 19: 1168-72.
35. Roccatello D, Mengozzi G, Alfieri V, et al. Early increase in blood nitric oxide, detected by electron paramagnetic resonance as nitrosylhaemoglobin, in haemodialysis. Nephrol Dial Transplant 1997; 12: 292-7.
36. Yokokawa K, Mankus R, Saklayen MG, et al. Increased nitric oxide production in patients with hypotension during hemodialysis. Ann Intern Med 1995; 123: 35-7.
37. Madore F, Prud'homme L, Austin JS, et al. Impact of nitric oxide on blood pressure in haemodialysis patients. Am J Kidney Dis 1997; 30: 665-71.
38. Sumino H, Sato K, Sakamaki T, et al. Reduced production of nitric oxide during haemodialysis. J Hum Hypertens 1999; 13: 437-42.
39. Kang ES, Acchiardo SR, Wang YB, Tevlin MT, Hughes T, Cardoso S. Hypotension during hemodialysis: role for nitric oxide. Am J Med Sci 1997; 313: 138-46.
40. Passauer J, Bussemaker E, Range U, Plug M, Gross P. Evidence in vivo showing increase of baseline nitric oxide generation and impairment of endothelium-dependent vasodilation in normotensive patients on chronic hemodialysis. J Am Soc Nephrol 2000; 11: 1726-34.
41. Sakata N, Imanaga Y, Meng J, et al. Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease. Atherosclerosis 1999; 142: 67-77.
42. Boaz S, Smetana S, Weinstein T, et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000; 356: 1213-8.