Synthesis of 14C-labelled EM-800 (SCH 57050) and EM-652 · HCl (SCH 57068 · HCl, acolbifene), pure selective estrogen receptor modulators

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 47, Issue 11, 2004, Pages 741-752

  Sancéau, Jean Yves ^a   Labrie, Fernand ^a   Gauthier, Sylvain ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Carbon 14; EM 652 HCl; EM 800; Radiochemical resolution; SERM

Indexed keywords

BENZENE RING; CARBON 14; EM-652·HCL; EM-800; LABELINGS; ORALLY ACTIVE; RADIOCHEMICAL RESOLUTION; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SERM; SYNTHESISED;

CARBON;

4 [4 METHYL 2 [4 [2 (1 PIPERIDINYL)ETHOXY]PHENYL] 7 PIVALOYLOXY 2H 1 BENZOPYRAN 3 YLPHENYL] PIVALATE; ACOLBIFENE; AMINE; CAMPHOR; CARBON 14; RESORCINOL; SCH 57050; SCH 57068; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BREAST CANCER; DRUG LABELING; DRUG PURITY; DRUG STRUCTURE; FRIEDEL CRAFTS REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KNOEVENAGEL CONDENSATION; RACEMIZATION; RADIOLYSIS; REPRODUCIBILITY; SYNTHESIS; UTERUS CANCER;

EID: 7044247706     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.862     Document Type: Article

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