RegM is required for optimal fructosyltransferase and glucosyltransferase gene expression in Streptococcus mutans

FEMS Microbiology Letters

Volumn 240, Issue 1, 2004, Pages 75-79

  Browngardt, Christopher M ^a   Wen, Zezhang T ^a   Burne, Robert A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Adherence; Biofilm; Dental caries; Exopolysaccharides; Virulence

Indexed keywords

CARBOHYDRATE; FRUCTOSYLTRANFERASE; GLUCOSYLTRANSFERASE; PROTEIN A; TRANSFERASE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CHEMOSTAT; CONTROLLED STUDY; CULTURE MEDIUM; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE FUSION; GENE INACTIVATION; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; REPORTER GENE; SENSITIVITY ANALYSIS; STREPTOCOCCUS MUTANS;

BACTERIAL PROTEINS; CARBOHYDRATE METABOLISM; DENTAL CARIES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSYLTRANSFERASES; HEXOSYLTRANSFERASES; HYDROGEN-ION CONCENTRATION; REPRESSOR PROTEINS; STREPTOCOCCUS MUTANS; VIRULENCE;

BACTERIA (MICROORGANISMS); EQUIDAE; STREPTOCOCCUS; STREPTOCOCCUS MUTANS;

EID: 7044235825     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2004.09.012     Document Type: Article

References (27)

1. H.K. Kuramitsu Virulence factors of mutans streptococci: role of molecular genetics Crit. Rev. Oral Biol. Med. 4 1993 159 176
2. J.A. Banas, and M.M. Vickerman Glucan-binding proteins of the oral streptococci Crit. Rev. Oral Biol. Med. 14 2003 89 99
3. R.A. Burne Oral streptococci...products of their environment J. Dent. Res. 77 1998 445 452
4. R. Rozen, D. Steinberg, and G. Bachrach Streptococcus mutans fructosyltransferase interactions with glucans FEMS Microbiol. Lett. 232 2004 39 43
5. Y. Yamashita, W.H. Bowen, R.A. Burne, and H.K. Kuramitsu Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model Infect. Immun. 61 1993 3811 3817
6. C. Munro, S.M. Michalek, and F.L. Macrina Cariogenicity of Streptococcus mutans V403 glucosyltransferase and fructosyltransferase mutants constructed by allelic exchange Infect. Immun. 59 1991 2316 2323
7. D.L. Kiska, and F.L. Macrina Genetic regulation of fructosyltransferase in Streptococcus mutans Infect. Immun. 62 1994 1241 1251
8. D.L. Wexler, M.C. Hudson, and R.A. Burne Streptococcus mutans fructosyltransferase (ftf) and glucosyltransferase (gtfBC) operon fusion strains in continuous culture Infect. Immun. 61 1993 1259 1267
9. Y. Li, and R.A. Burne Regulation of the gtfBC and ftf genes of Streptococcus mutans in biofilms in response to pH and carbohydrate Microbiology 147 2001 2841 2848
10. I. Martin-Verstraete, J. Stulke, A. Klier, and G. Rapoport Two different mechanisms mediate catabolite repression of the Bacillus subtilis levanase operon J. Bacteriol. 177 1995 6919 6927
11. J. Stulke, and W. Hillen Coupling physiology and gene regulation in bacteria: the phosphotransferase sugar uptake system delivers the signals Naturwissenschaften 85 1998 583 592
12. S. Tobisch, D. Zuhlke, J. Bernhardt, J. Stulke, and M. Hecker Role of CcpA in regulation of the central pathways of carbon catabolism in Bacillus subtilis J. Bacteriol. 181 1999 6996 7004
13. A.J. Turinsky, T.R. Moir-Blais, F.J. Grundy, and T.M. Henkin Bacillus subtilis ccpA gene mutants specifically defective in activation of acetoin biosynthesis J. Bacteriol. 182 2000 5611 5614
14. H. Ludwig, N. Rebhan, H.M. Blencke, M. Merzbacher, and J. Stulke Control of the glycolytic gapA operon by the catabolite control protein A in Bacillus subtilis: a novel mechanism of CcpA-mediated regulation Mol. Microbiol. 45 2002 543 553
15. I. Wacker, H. Ludwig, I. Reif, H.M. Blencke, C. Detsch, and J. Stulke The regulatory link between carbon and nitrogen metabolism in Bacillus subtilis: regulation of the gltAB operon by the catabolite control protein CcpA Microbiology 149 2003 3001 3009
16. C.L. Simpson, and R.R. Russell Identification of a homolog of CcpA catabolite repressor protein in Streptococcus mutans Infect. Immun. 66 1998 2085 2092
17. Z.T. Wen, and R.A. Burne Analysis of cis- and trans-acting factors involved in regulation of the Streptococcus mutans fructanase gene (fruA) J. Bacteriol. 184 2002 126 133
18. Z.T. Wen, and R.A. Burne Functional genomics approach to identifying genes required for biofilm development by Streptococcus mutans Appl. Environ. Microbiol. 68 2002 1196 1203
19. R.A. Burne, Z.T. Wen, Y.M. Chen, and J.E.C. Penders Regulation of expression of the fructan hydrolase gene of Streptococcus mutans GS-5 by induction and carbon catabolite repression J. Bacteriol. 181 1999 2863 2871
20. M.C. Hudson, and R. Curtiss Regulation of expression of Streptococcus mutans genes important to virulence Infect. Immun. 58 1990 464 470
21. Y.Y. Chen, M.J. Betzenhauser, and R.A. Burne cis-Acting elements that regulate the low-pH-inducible urease operon of Streptococcus salivarius Microbiology 148 2002 3599 3608
22. W.V. Shaw Chloramphenicol acetyltransferase activity from chloramphenicol-resistant bacteria Methods Enzymol. 43 1979 737 755
23. N. Hanada, and H.K. Kuramitsu Isolation and characterization of the Streptococcus mutans gtfC gene, coding for the synthesis of both soluble and insoluble glucans Infect. Immun. 56 1988 1999 2005
24. Man of the sugar phosphotransferase system Appl. Environ. Microbiol. 69 2003 4760 4769
25. H. Ludwig, and J. Stulke The Bacillus subtilis catabolite control protein CcpA exerts all its regulatory functions by DNA-binding FEMS Microbiol. Lett. 203 2001 125 129
26. S. Bachem, and J. Stulke Regulation of the Bacillus subtilis GlcT antiterminator protein by components of the phosphotransferase system J. Bacteriol. 180 1998 5319 5326
27. M.J. Weickert, and G.H. Chambliss Genetic analysis of the promoter region of the Bacillus subtilis alpha-amylase gene J. Bacteriol. 171 1989 3656 3666