Synthesis and evaluations of pentahydroxylhexyl-L-cysteine and its dimer as chelating agents for cadmium or lead decorporation

Toxicology and Applied Pharmacology

Volumn 200, Issue 3, 2004, Pages 229-236

  Wang, Chao ^a   Zhao, Ming ^a   Yang, Jian ^a   Li, Xingwei ^b   Peng, Shiqi ^c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Huamei Pharmaceutical Co LTD   (China)

^c Cap Univ of Medicinal Sciences   (China)

Author keywords

Antagonists; Cadmium; Lead

Indexed keywords

ACETYLCYSTEINE; CADMIUM; CHELATING AGENT; DIMER; LEAD; N (2,3,4,5,6 PENTAHYDROXYLHEXYL)CYSTEINE; N,N' BIS(2,3,4,5,6 PENTAHYDROXYLHEXYL)CYSTEINE; PENICILLAMINE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; BONE MARROW; CADMIUM POISONING; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG PENETRATION; DRUG POTENCY; DRUG SYNTHESIS; FEEDING; FEMALE; KIDNEY CORTEX; LD 50; LEAD POISONING; MALE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PH; RAT; SPERMATOZOON ABNORMALITY;

ANIMALS; BONE MARROW CELLS; CACO-2 CELLS; CADMIUM POISONING; CHELATING AGENTS; CYSTEINE; FEMALE; HUMANS; INDICATORS AND REAGENTS; INJECTIONS, INTRAPERITONEAL; LEAD POISONING; LETHAL DOSE 50; MALE; MICE; MICRONUCLEUS TESTS; POTENTIOMETRY; RATS; RATS, WISTAR; SPERMATOZOA; TISSUE DISTRIBUTION;

EID: 7044233144     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.04.009     Document Type: Article

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