β2-Glycoprotein I and LDL-receptor family members

Thrombosis Research

Volumn 114, Issue 5-6 SPEC. ISS., 2004, Pages 455-459

  De Groot, Philip G ^a   Van Lummel, Menno ^a   Pennings, Maarten ^a   Urbanus, Rolf ^a   Bas De Laat, H ^a   Lenting, Peter J ^a   Derksen, Ronald H W M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Antiphospholipid syndrome; LDL receptor family; 2 Glycoprotein

Indexed keywords

BETA2 GLYCOPROTEIN 1; BETA2 GLYCOPROTEIN 1 ANTIBODY; CELL SURFACE RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; LUPUS ANTICOAGULANT; MEGALIN; PHOSPHOLIPID ANTIBODY; PROTHROMBIN; VERY LOW DENSITY LIPOPROTEIN; GLYCOPROTEIN;

ANTIPHOSPHOLIPID SYNDROME; BLEEDING; BLOOD CLOTTING TIME; CELL SURFACE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IN VITRO STUDY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; REVIEW; RISK FACTOR; THROMBOCYTE ACTIVATION; THROMBOEMBOLISM; THROMBOGENICITY; ANIMAL; BIOLOGICAL MODEL; BLOOD; CHEMISTRY; IMMUNOLOGY; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANTIBODIES, ANTIPHOSPHOLIPID; BETA 2-GLYCOPROTEIN I; GLYCOPROTEINS; HUMANS; MODELS, BIOLOGICAL; PLATELET ACTIVATION; RECEPTORS, LDL; THROMBOEMBOLISM;

EID: 7044231043     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2004.06.015     Document Type: Article

References (30)

1. Roubey R.A. Update on antiphospholipid antibodies. Curr. Opin. Rheumatol. 12:2000;74-78
2. Arnout J., Vermylen J. Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic disease. J. Thromb. Haemost. 1:2003;931-942
3. Espinosa G., Cervera R., Font J., Shoenfeld Y. Antiphospholipid syndrome: pathogenic mechanisms. Autoimmun. Rev. 2:2003;86-93
4. 2-glycoprotein I dependent lupus anticoagulant highly correlates with thrombosis in the Antiphospholipid Syndrome. Blood 2004; submitted for publication.
5. 2glycoprotein I. Proc. Natl. Acad. Sci. U. S. A. 87:1990;4120-4124
6. Galli M., Comfurius P., Maassen C., Hemker H.C., De Baets M.H., Van Breda-Vriesman P.J.C., et al. Anticardiolipin antibodies (ACA) are directed not to cardiolipin but to a plasma cofactor. Lancet. 335:1990;1544-1547
7. 2-I. Glycoproteine. Thromb. Haemost. 67:1992;499-502
8. Bevers E.M., Galli M., Barbui T., Comfurius P., Zwaal R.F. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost. 66:1991;629-632
9. Galli M., Luciani D., Bertolini G., Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood. 101:2003;1827-1832
10. 2-glycoprotein I complexes to lipid membranes. Biochemistry. 35:1996;13833-13842
11. Simmelink M.J., Horbach D.A., Derksen R.H., Meijers J.C., Bevers E.M., Willems G.M., et al. Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces. Br. J. Haematol. 113:2001;621-629
12. Esmon C.T. Regulation of blood coagulation. Biochim. Biophys. Acta. 1477:2000;349-360
13. 2-glycoprotein I antibody complexes. J. Biol. Chem. 276:2001;3060-3067
14. Ma K., Simantov R., Zhang J.C., Silverstein R., Hajjar K.A., McCrae K.R. High affinity binding of beta2-glycoprotein I to human endothelial cells is mediated by annexin II. J. Biol. Chem. 275:2000;15541-15548
15. 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2′ J. Biol. Chem. 278:2003;33831-33838
16. Raschi E., Testoni C., Bosisio D., Borghi M.O., Koike T., Mantovani A., et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood. 101:2003;3495-3500
17. Jackson S.P., Schoenwaelder S.M. Antiplatelet therapy: in search of the 'magic bullet'. Nat. Rev., Drug Discov. 2:2003;775-789
18. FitzGerald G.A., Austin S., Egan K., Cheng Y., Pratico D. Cyclo-oxygenase products and atherothrombosis. Ann. Med. 32(Suppl. 1):2000;21-26
19. Forastiero R., Martinuzzo M., Carreras L.O., Maclouf J. Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites. Thromb. Haemost. 79:1998;42-45
20. Martinuzzo M.E., Maclouf J., Carreras L.O., Levy-Toledano S. Antiphospholipid antibodies enhance thrombin-induced platelet activation and thromboxane formation. Thromb. Haemost. 70:1993;667-671
21. Joseph J.E., Donohoe S., Harrison P., Mackie I.J., Machin S.J. Platelet activation and turnover in the primary antiphospholipid syndrome. Lupus. 7:1998;333-340
22. Jankowski M., Vreys I., Wittevrongel C., Boon D., Vermylen J., Hoylaerts M.F., et al. Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood. 101:2003;157-162
23. Riddell D.R., Vinogradov D.V., Stannard A.K., Chadwick N., Owen J.S. Identification and characterization of LRP8 (apoER2) in human blood platelets. J. Lipid Res. 40:1999;1925-1930
24. Ma K., Simantov R., Zhang J.C., Silverstein R., Hajjar K.A., McCrae K.R. High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J. Biol. Chem. 275:2000;15541-15548
25. Krieger M., Stern D.M. Series introduction: multiligand receptors and human disease. J. Clin. Invest. 108:2001;645-647
26. Herz J., Strickland D.K. LRP: a multifunctional scavenger and signaling receptor. J. Clin. Invest. 108:2001;779-784
27. Schneider W.J., Nimpf J. LDL receptor relatives at the crossroad of endocytosis and signaling. Cell. Mol. Life Sci. 60:2003;892-903
28. Relou A.M., Gorter G., van Rijn H.J., Akkerman J.W. Platelet activation by the apoB/E receptor-binding domain of LDL. Thromb. Haemost. 87:2002;880-887
29. Guerin J., Sheng Y., Reddel S., Iverson G.M., Chapman M.G., Krilis S.A. Heparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome. J. Biol. Chem. 277:2002;2644-2649
30. Wang S.X., Sun Y.T., Sui S.F. Membrane induced conformational changes in human apolipoprotein H. Biochem. J. 348:2000;103-106