1-Methylgalanthamine derivatives

Monatshefte fur Chemie

Volumn 135, Issue 10, 2004, Pages 1275-1287

  Hemetsberger, Margit ^a   Treu, Matthias ^a   Jordis, Ulrich ^a   Mereiter, Kurt ^a   Hametner, Christian ^a   Fröhlich, Johannes ^a  

^a VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Acetylcholine esterase inhibitor; Drug research; Galanthamine analogue; Tandem cyclization; Total synthesis

Indexed keywords

GALANTAMINE;

ARTICLE; DRUG SYNTHESIS;

EID: 7044227905     PISSN: 00269247     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00706-004-0220-8     Document Type: Article

References (12)

1. Raskind MA, Peskind ER, Wessel T, Yuan W, Allen FH, Aronson SM, Baumel B, Eisner L, Brenner R, Cheren S, Verma S, Daniel DG, DePriest M, Ferguson JM, England D, Farmer MV, Frey J, Flitman SS, Harrell LE, Holub R, Jacobson A, Olivera GF, Ownby RL, Jenkyn LR, Landbloom R, Leibowitz MT, Zolnouni PP, Lyketosos C, Mintzer JE, Nakra R, Pahl JJ, Potkin SG, Richardson BC, Richter RW, Rymer MM, Saur DP, Daffner KR, Scinto L, Stoukides J, Targum SD, Thein SG, Thien SG, Tomlinson JR (2000) Neurology 54: 2261
2. Moghul S, Wilkinson D (2001) Expert Review of Neurotherapeutics 1: 61
3. Bores GM, Kosley RW (1996) Drugs Future 21: 621
4. Kueenburg B, Czollner L, Froehlich J, Jordis U (1999) Org Process Res Dev 3: 425
5. Czollner L, Treu M, Froehlich J, Kueenburg B, Jordis U (2001) Arkivoc 2001 (i): 191
6. Scarpati ML, Bianco A, Mascitelli L, Passacantilli P (1990) Synth Commun 20: 2565
7. Jacques J, Collet A, Wilen SH (1994) Enantiomers, Racemates, and Resolutions. Krieger Publishing, Malabar, FL
8. Peeters OM, Baton NM, De Ranter CJ (1997) Acta Crystallogr Sect C 53: 1284
9. Bruker AXS: Programs SMART, v 5.054; SAINT, v 6.2.9; SADABS v 2.03; XPREP, v 5.1; SHELXTL, v 5.1. Bruker AXS Inc, Madison, WI, USA, 2001
10. Sheldrick GM (1997) SHELX97. Program system for crystal structure determination. University of Göttingen, Germany
11. CCDC 185482 and 185483 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/retrieving.html (or from the CCDC, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033; e-mail: deposit@ ccdc.cam.ac.uk)
12. -1, T = 297(2) K, R1 = 0.0524, wR2 = 0.1054 (all 4291 data)