Structural Abnormalities of the Pulmonary Trunk in Tetralogy of Fallot and Potential Clinical Implications. A Morphological Study

Journal of the American College of Cardiology

Volumn 54, Issue 20, 2009, Pages 1883-1890

  Bédard, Elisabeth ^a   McCarthy, Karen P ^a   Dimopoulos, Konstantinos ^a   Giannakoulas, Georgios ^a   Gatzoulis, Michael A ^a   Ho, Siew Yen ^a  

^a Unit of Cardiac Morphology   (United Kingdom)

Author keywords

arteries; structure; tetralogy of Fallot; tissue

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FALLOT TETRALOGY; FEMALE; FETUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFANT; MALE; MICROSCOPY; PALLIATIVE THERAPY; PLASTIC SURGERY; PRESCHOOL CHILD; PRIORITY JOURNAL; PULMONARY VALVE ATRESIA; PULMONARY VALVE DISEASE; PULMONARY VALVE STENOSIS; SCHOOL CHILD; SCORING SYSTEM;

ADOLESCENT; ADULT; AGED; AGING; AORTA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; ELASTIC TISSUE; FEMALE; FETAL DISEASES; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; PALLIATIVE CARE; PULMONARY ARTERY; TETRALOGY OF FALLOT; TUNICA MEDIA; YOUNG ADULT;

EID: 70350776627     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.06.040     Document Type: Article

References (37)

1. Gatzoulis M.A. Tetralogy of Fallot. In: Gatzoulis M., Webb G., and Daubeney P. (Eds). Diagnosis and Management of Adult Congenital Heart Disease (2003), Elsevier, London 315-326
2. Therrien J., and Webb G. Clinical update on adults with congenital heart disease. Lancet 362 (2003) 1305-1313
3. Hoffman J.I., and Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol 39 (2002) 1890-1900
4. Nollert G., Fischlein T., Bouterwek S., Bohmer C., Klinner W., and Reichart B. Long-term survival in patients with repair of tetralogy of Fallot: 36-year follow-up of 490 survivors of the first year after surgical repair. J Am Coll Cardiol 30 (1997) 1374-1383
5. Tan J.L., Davlouros P.A., McCarthy K.P., Gatzoulis M.A., and Ho S.Y. Intrinsic histological abnormalities of aortic root and ascending aorta in tetralogy of Fallot: evidence of causative mechanism for aortic dilatation and aortopathy. Circulation 112 (2005) 961-968
6. Niwa K., Siu S.C., Webb G.D., and Gatzoulis M.A. Progressive aortic root dilatation in adults late after repair of tetralogy of Fallot. Circulation 106 (2002) 1374-1378
7. Tan J.L., Gatzoulis M.A., and Ho S.Y. Aortic root disease in tetralogy of Fallot. Curr Opin Cardiol 21 (2006) 569-572
8. Senzaki H., Iwamoto Y., Ishido H., et al. Arterial haemodynamics in patients after repair of tetralogy of Fallot: influence on left ventricular after load and aortic dilatation. Heart 94 (2008) 70-74
9. Cheung Y.F., Ou X., and Wong S.J. Central and peripheral arterial stiffness in patients after surgical repair of tetralogy of Fallot: implications for aortic root dilatation. Heart 92 (2006) 1827-1830
10. Frigiola A., Redington A.N., Cullen S., and Vogel M. Pulmonary regurgitation is an important determinant of right ventricular contractile dysfunction in patients with surgically repaired tetralogy of Fallot. Circulation 110 (2004) II153-II157
11. Gatzoulis M.A., Balaji S., Webber S.A., et al. Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study. Lancet 356 (2000) 975-981
12. Geva T., Sandweiss B.M., Gauvreau K., Lock J.E., and Powell A.J. Factors associated with impaired clinical status in long-term survivors of tetralogy of Fallot repair evaluated by magnetic resonance imaging. J Am Coll Cardiol 43 (2004) 1068-1074
13. Gatzoulis M.A., Till J.A., Somerville J., and Redington A.N. Mechanoelectrical interaction in tetralogy of Fallot. QRS prolongation relates to right ventricular size and predicts malignant ventricular arrhythmias and sudden death. Circulation 92 (1995) 231-237
14. Heath D., Wood E.H., Dushane J.W., and Edwards J.E. The structure of the pulmonary trunk at different ages and in cases of pulmonary hypertension and pulmonary stenosis. J Pathol Bacteriol 77 (1959) 443-456
15. Plank L., James J., and Wagenvoort C.A. Caliber and elastin content of the pulmonary trunk. Arch Pathol Lab Med 104 (1980) 238-241
16. Niwa K., Perloff J.K., Bhuta S.M., et al. Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses. Circulation 103 (2001) 393-400
17. Schlatmann T.J., and Becker A.E. Histologic changes in the normal aging aorta: implications for dissecting aortic aneurysm. Am J Cardiol 39 (1977) 13-20
18. de Sa M., Moshkovitz Y., Butany J., and David T.E. Histologic abnormalities of the ascending aorta and pulmonary trunk in patients with bicuspid aortic valve disease: clinical relevance to the Ross procedure. J Thorac Cardiovasc Surg 118 (1999) 588-594
19. Tredal S.M., Carter J.B., and Edwards J.E. Cystic medial necrosis of the pulmonary artery: association with pulmonary hypertension. Arch Pathol 97 (1974) 183-186
20. Farrar J.F., Blomfield J., and Reye R.D. The structure and composition of the pulmonary circulation in congenital heart disease. J Pathol Bacteriol 90 (1965) 97-105
21. Therrien J., Siu S.C., McLaughlin P.R., Liu P.P., Williams W.G., and Webb G.D. Pulmonary valve replacement in adults late after repair of tetralogy of Fallot: are we operating too late?. J Am Coll Cardiol 36 (2000) 1670-1675
22. Davlouros P.A., Kilner P.J., Hornung T.S., et al. Right ventricular function in adults with repaired tetralogy of Fallot assessed with cardiovascular magnetic resonance imaging: detrimental role of right ventricular outflow aneurysms or akinesia and adverse right-to-left ventricular interaction. J Am Coll Cardiol 40 (2002) 2044-2052
23. Gatzoulis M.A., Clark A.L., Cullen S., Newman C.G., and Redington A.N. Right ventricular diastolic function 15 to 35 years after repair of tetralogy of Fallot. Restrictive physiology predicts superior exercise performance. Circulation 91 (1995) 1775-1781
24. Redington A.N. Determinants and assessment of pulmonary regurgitation in tetralogy of Fallot: practice and pitfalls. Cardiol Clin 24 (2006) 631-639 vii
25. Chaturvedi R.R., Kilner P.J., White P.A., Bishop A., Szwarc R., and Redington A.N. Increased airway pressure and simulated branch pulmonary artery stenosis increase pulmonary regurgitation after repair of tetralogy of Fallot. Real-time analysis with a conductance catheter technique. Circulation 95 (1997) 643-649
26. Johnson R.J., and Haworth S.G. Pulmonary vascular and alveolar development in tetralogy of Fallot: a recommendation for early correction. Thorax 37 (1982) 893-901
27. Harris P., Heath D., and Apostolopoulos A. Extensibility of the pulmonary trunk in heart disease. Br Heart J 27 (1965) 660-666
28. Rosenberg H.G., Williams W.G., Trusler G.A., Higa T., and Rabinovitch M. Structural composition of central pulmonary arteries. Growth potential after surgical shunts. J Thorac Cardiovasc Surg 94 (1987) 498-503
29. Chong W.Y., Wong W.H., Chiu C.S., and Cheung Y.F. Aortic root dilation and aortic elastic properties in children after repair of tetralogy of Fallot. Am J Cardiol 97 (2006) 905-909
30. Nollen G.J., Groenink M., Tijssen J.G., Van Der Wall E.E., and Mulder B.J. Aortic stiffness and diameter predict progressive aortic dilatation in patients with Marfan syndrome. Eur Heart J 25 (2004) 1146-1152
31. Nistri S., Sorbo M.D., Basso C., and Thiene G. Bicuspid aortic valve: abnormal aortic elastic properties. J Heart Valve Dis 11 (2002) 369-373 discussion 373-4
32. Grotenhuis H.B., Ottenkamp J., Westenberg J.J., Bax J.J., Kroft L.J., and de Roos A. Reduced aortic elasticity and dilatation are associated with aortic regurgitation and left ventricular hypertrophy in nonstenotic bicuspid aortic valve patients. J Am Coll Cardiol 49 (2007) 1660-1665
33. Segura A.M., Luna R.E., Horiba K., et al. Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan's syndrome. Circulation 98 (1998) II331-II337 discussion II337-8
34. Chowdhury U.K., Mishra A.K., Balakrishnan P., et al. Role of fibrillin-1 genetic mutations and polymorphism in aortic dilatation in patients undergoing intracardiac repair of tetralogy of Fallot. J Thorac Cardiovasc Surg 136 (2008) 757-766 766.e1-10
35. Bonderman D., Gharehbaghi-Schnell E., Wollenek G., Maurer G., Baumgartner H., and Lang I.M. Mechanisms underlying aortic dilatation in congenital aortic valve malformation. Circulation 99 (1999) 2138-2143
36. Nataatmadja M., West M., West J., et al. Abnormal extracellular matrix protein transport associated with increased apoptosis of vascular smooth muscle cells in Marfan syndrome and bicuspid aortic valve thoracic aortic aneurysm. Circulation 108 Suppl 1 (2003) II329-II334
37. Garg V. Molecular genetics of aortic valve disease. Curr Opin Cardiol 21 (2006) 180-184