Proteomic analysis of microdissected facial nuclei of the rat following facial nerve injury

Journal of Neuroscience Methods

Volumn 185, Issue 1, 2009, Pages 23-28

  Melle, Christian ^a   Ernst, Günther ^a   Grosheva, Maria ^b   Angelov, Doychin N ^c   Irintchev, Andrey ^a   Guntinas Lichius, Orlando ^a   von Eggeling, Ferdinand ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Axotomy; Imaging; MALDI; Microdissection; Nucleus facialis; SELDI

Indexed keywords

PROTEIN HYDROLYSATE;

AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FACIAL NERVE INJURY; FACIAL NERVE NUCLEUS; FEMALE; FROZEN SECTION; INTERMETHOD COMPARISON; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICRODISSECTION; MOTONEURON; NERVE FIBER TRANSECTION; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEOMICS; RAT; SENSITIVITY AND SPECIFICITY; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TISSUE SECTION;

ANIMALS; AXOTOMY; CHROMATOGRAPHY, AFFINITY; DISEASE MODELS, ANIMAL; FACIAL NERVE; FACIAL NERVE INJURIES; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; LASERS; MICRODISSECTION; MICROTOMY; MOTOR NEURONS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; RATS; RATS, WISTAR; RHOMBENCEPHALON;

EID: 70350728398     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.09.003     Document Type: Article

References (21)

1. Busch A., Michel S., Hoppe C., Driesch D., Claussen U., and von Eggeling F. Proteome analysis of maternal serum samples for trisomy 21 pregnancies using ProteinChip Arrays and bioinformatics. J Histochem Cytochem 53 (2005) 341-343
2. Chaurand P., Sanders M.E., Jensen R.A., and Caprioli R.M. Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol 165 (2004) 1057-1068
3. Ernst G., Melle C., Schimmel B., Bleul A., and von Eggeling F. Proteohistography-direct analysis of tissue with high sensitivity and high spatial resolution using proteinchip technology. J Histochem Cytochem 54 (2006) 13-17
4. Fu S.Y., and Gordon T. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol 14 (1997) 67-116
5. Guntinas-Lichius O. The facial nerve in the presence of a head and neck neoplasm: assessment and outcome after surgical management. Curr Opin Otolaryngol Head Neck Surg 12 (2004) 133-141
6. Guntinas-Lichius O., Irintchev A., Streppel M., Lenzen M., Grosheva M., Wewetzer K., et al. Factors limiting motor recovery after facial nerve transection in the rat: combined structural and functional analyses. Eur J Neurosci 21 (2005) 391-402
7. Guntinas-Lichius O., Neiss W.F., Gunkel A., and Stennert E. Differences in glial, synaptic and motoneuron responses in the facial nucleus of the rat brainstem following facial nerve resection and nerve suture reanastomosis. Eur Arch Otorhinolaryngol 251 (1994) 410-417
8. Makwana M., and Raivich G. Molecular mechanisms in successful peripheral regeneration. FEBS J 272 (2005) 2628-2638
9. Melle C., Ernst G., Escher N., Hartmann D., Schimmel B., Bleul A., et al. Protein profiling of microdissected pancreas carcinoma and identification of HSP27 as a potential serum marker. Clin Chem 53 (2007) 629-635
10. Melle C., Ernst G., Scheibner O., Kaufmann R., Schimmel B., Bleul A., et al. Identification of specific protein markers in microdissected hepatocellular carcinoma. J Proteome Res 6 (2007) 306-315
11. Melle C., Ernst G., Schimmel B., Bleul A., Thieme H., Kaufmann R., et al. Discovery and identification of alpha-defensins as low abundant, tumor-derived serum markers in colorectal cancer. Gastroenterology 129 (2005) 66-73
12. Paweletz C.P., Trock B., Pennanen M., Tsangaris T., Magnant C., Liotta L.A., et al. Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: potential for new biomarkers to aid in the diagnosis of breast cancer. Dis Markers 17 (2001) 301-307
13. Petricoin E.F., Ardekani A.M., Hitt B.A., Levine P.J., Fusaro V.A., Steinberg S.M., et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359 (2002) 572-577
14. Petricoin E.F., Mills G.B., Kohn E.C., and Liotta L.A. Proteomic patterns in serum and identification of ovarian cancer-reply. Lancet 360 (2002) 170-171
15. Raivich G., and Makwana M. The making of successful axonal regeneration: genes, molecules and signal transduction pathways. Brain Res Rev 53 (2007) 287-311
16. Rosty C., Christa L., Kuzdzal S., Baldwin W.M., Zahurak M.L., Carnot F., et al. Identification of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein I as a biomarker for pancreatic ductal adenocarcinoma by protein biochip technology. Cancer Res 62 (2002) 1868-1875
17. Schütze K., and Lahr G. Identification of expressed genes by laser-mediated manipulation of single cells. Nat Biotechnol 16 (1998) 737-742
18. Sitek B., Potthoff S., Schulenborg T., Stegbauer J., Vinke T., Rump L.C., et al. Novel approaches to analyse glomerular proteins from smallest scale murine and human samples using DIGE saturation labelling. Proteomics 6 (2006) 4337-4345
19. Vlahou A., Schellhammer P.F., Mendrinos S., Patel K., Kondylis F.I., Gong L., et al. Development of a novel proteomic approach for the detection of transitional cell carcinoma of the bladder in urine. Am J Pathol 158 (2001) 1491-1502
20. von Eggeling F., Melle C., and Ernst G. Microdissecting the proteome. Proteomics 7 (2007) 2729-2737
21. von Eggeling F., Junker K., Fiedler W., Wollscheid V., Durst M., Claussen U., et al. Mass spectrometry meets chip technology: a new proteomic tool in cancer research?. Electrophoresis 22 (2001) 2898-2902