메뉴 건너뛰기




Volumn 127, Issue 1, 2009, Pages 33-38

LIGHT protein suppresses tumor growth by augmentation of immune response

Author keywords

Cancer immunotherapy; Cytokine; Protein therapy; Recombinant protein; Tumor necrosis factor

Indexed keywords

GAMMA INTERFERON; LIGHT PROTEIN; PROTEIN; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 70350704674     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.08.010     Document Type: Article
Times cited : (9)

References (36)
  • 1
    • 3042785982 scopus 로고    scopus 로고
    • Recent progress on tumor missile therapy and tumor vascular targeting therapy as a new approach
    • Yoshioka Y., Tsutsumi Y., Nakagawa S., and Mayumi T. Recent progress on tumor missile therapy and tumor vascular targeting therapy as a new approach. Curr Vasc Pharmacol 2 (2004) 259-270
    • (2004) Curr Vasc Pharmacol , vol.2 , pp. 259-270
    • Yoshioka, Y.1    Tsutsumi, Y.2    Nakagawa, S.3    Mayumi, T.4
  • 5
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn G.P., Koebel C.M., and Schreiber R.D. Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6 (2006) 836-848
    • (2006) Nat Rev Immunol , vol.6 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 6
    • 49949152063 scopus 로고    scopus 로고
    • Targeting tumors with LIGHT to generate metastasis-clearing immunity
    • Yu P., and Fu Y.X. Targeting tumors with LIGHT to generate metastasis-clearing immunity. Cytokine Growth Factor Rev 19 (2008) 285-294
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 285-294
    • Yu, P.1    Fu, Y.X.2
  • 7
    • 65349113104 scopus 로고    scopus 로고
    • Immunoregulation by tumor necrosis factor superfamily member LIGHT
    • Wang Y., Zhu M., Miller M., and Fu Y.X. Immunoregulation by tumor necrosis factor superfamily member LIGHT. Immunol Rev 229 (2009) 232-243
    • (2009) Immunol Rev , vol.229 , pp. 232-243
    • Wang, Y.1    Zhu, M.2    Miller, M.3    Fu, Y.X.4
  • 8
    • 64249144692 scopus 로고    scopus 로고
    • Targeted cancer immunotherapy using ligands of the tumor necrosis factor super-family
    • Bremer E., de Bruyn M., Wajant H., and Helfrich W. Targeted cancer immunotherapy using ligands of the tumor necrosis factor super-family. Curr Drug Targets 10 (2009) 94-103
    • (2009) Curr Drug Targets , vol.10 , pp. 94-103
    • Bremer, E.1    de Bruyn, M.2    Wajant, H.3    Helfrich, W.4
  • 9
    • 0042914703 scopus 로고    scopus 로고
    • Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    • Yang J.C., Sherry R.M., Steinberg S.M., Topalian S.L., Schwartzentruber D.J., Hwu P., et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol 21 (2003) 3127-3132
    • (2003) J Clin Oncol , vol.21 , pp. 3127-3132
    • Yang, J.C.1    Sherry, R.M.2    Steinberg, S.M.3    Topalian, S.L.4    Schwartzentruber, D.J.5    Hwu, P.6
  • 10
    • 0031924595 scopus 로고    scopus 로고
    • Phase I trial of subcutaneous recombinant human interleukin-12 in patients with advanced renal cell carcinoma
    • Motzer R.J., Rakhit A., Schwartz L.H., Olencki T., Malone T.M., Sandstrom K., et al. Phase I trial of subcutaneous recombinant human interleukin-12 in patients with advanced renal cell carcinoma. Clin Cancer Res 4 (1998) 1183-1191
    • (1998) Clin Cancer Res , vol.4 , pp. 1183-1191
    • Motzer, R.J.1    Rakhit, A.2    Schwartz, L.H.3    Olencki, T.4    Malone, T.M.5    Sandstrom, K.6
  • 11
    • 0030070734 scopus 로고    scopus 로고
    • Eastern Cooperative Group Trial of interferon gamma in metastatic melanoma: an innovative study design
    • Schiller J.H., Pugh M., Kirkwood J.M., Karp D., Larson M., and Borden E. Eastern Cooperative Group Trial of interferon gamma in metastatic melanoma: an innovative study design. Clin Cancer Res 2 (1996) 29-36
    • (1996) Clin Cancer Res , vol.2 , pp. 29-36
    • Schiller, J.H.1    Pugh, M.2    Kirkwood, J.M.3    Karp, D.4    Larson, M.5    Borden, E.6
  • 12
    • 33644646423 scopus 로고    scopus 로고
    • The role of stroma in immune recognition and destruction of well-established solid tumors
    • Yu P., Rowley D.A., Fu Y.X., and Schreiber H. The role of stroma in immune recognition and destruction of well-established solid tumors. Curr Opin Immunol 18 (2006) 226-231
    • (2006) Curr Opin Immunol , vol.18 , pp. 226-231
    • Yu, P.1    Rowley, D.A.2    Fu, Y.X.3    Schreiber, H.4
  • 13
    • 0026547421 scopus 로고
    • Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells
    • Singh S., Ross S.R., Acena M., Rowley D.A., and Schreiber H. Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J Exp Med 175 (1992) 139-146
    • (1992) J Exp Med , vol.175 , pp. 139-146
    • Singh, S.1    Ross, S.R.2    Acena, M.3    Rowley, D.A.4    Schreiber, H.5
  • 15
    • 0031907988 scopus 로고    scopus 로고
    • LIGHT, a new member of the TNF superfamily, and lymphotoxin α are ligands for herpesvirus entry mediator
    • Mauri D.N., Ebner R., Montgomery R.I., Kochel K.D., Cheung T.C., Yu G.L., et al. LIGHT, a new member of the TNF superfamily, and lymphotoxin α are ligands for herpesvirus entry mediator. Immunity 8 (1998) 21-30
    • (1998) Immunity , vol.8 , pp. 21-30
    • Mauri, D.N.1    Ebner, R.2    Montgomery, R.I.3    Kochel, K.D.4    Cheung, T.C.5    Yu, G.L.6
  • 16
    • 15144341298 scopus 로고    scopus 로고
    • Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth
    • Harrop J.A., McDonnell P.C., Brigham-Burke M., Lyn S.D., Minton J., Tan K.B., et al. Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth. J Biol Chem 273 (1998) 27548-27556
    • (1998) J Biol Chem , vol.273 , pp. 27548-27556
    • Harrop, J.A.1    McDonnell, P.C.2    Brigham-Burke, M.3    Lyn, S.D.4    Minton, J.5    Tan, K.B.6
  • 18
    • 10744227434 scopus 로고    scopus 로고
    • Priming of naive T cells inside tumors leads to eradication of established tumors
    • Yu P., Lee Y., Liu W., Chin R.K., Wang J., Wang Y., et al. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat Immunol 5 (2004) 141-149
    • (2004) Nat Immunol , vol.5 , pp. 141-149
    • Yu, P.1    Lee, Y.2    Liu, W.3    Chin, R.K.4    Wang, J.5    Wang, Y.6
  • 19
    • 2942618536 scopus 로고    scopus 로고
    • Lymphotoxin-β receptor activation by activated T cells induces cytokine release from mouse bone marrow-derived mast cells
    • Stopfer P., Mannel D.N., and Hehlgans T. Lymphotoxin-β receptor activation by activated T cells induces cytokine release from mouse bone marrow-derived mast cells. J Immunol 172 (2004) 7459-7465
    • (2004) J Immunol , vol.172 , pp. 7459-7465
    • Stopfer, P.1    Mannel, D.N.2    Hehlgans, T.3
  • 20
    • 0034655166 scopus 로고    scopus 로고
    • LIGHT, a TNF-Like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response
    • Tamada K., Shimozaki K., Chapoval A.I., Zhai Y., Su J., Chen S.F., et al. LIGHT, a TNF-Like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J Immunol 164 (2000) 4105-4110
    • (2000) J Immunol , vol.164 , pp. 4105-4110
    • Tamada, K.1    Shimozaki, K.2    Chapoval, A.I.3    Zhai, Y.4    Su, J.5    Chen, S.F.6
  • 21
    • 0034640539 scopus 로고    scopus 로고
    • The lymphotoxin-β receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells
    • Rooney I.A., Butrovich K.D., Glass A.A., Borboroglu S., Benedict C.A., Whitbeck J.C., et al. The lymphotoxin-β receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells. J Biol Chem 275 (2000) 14307-14315
    • (2000) J Biol Chem , vol.275 , pp. 14307-14315
    • Rooney, I.A.1    Butrovich, K.D.2    Glass, A.A.3    Borboroglu, S.4    Benedict, C.A.5    Whitbeck, J.C.6
  • 23
    • 34547490647 scopus 로고    scopus 로고
    • Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants
    • Shibata H., Kamada H., Kobayashi-Nishibata K., Yoshioka Y., Nishibata T., Abe Y., et al. Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants. Biochim Biophys Acta 1774 (2007) 1029-1035
    • (2007) Biochim Biophys Acta , vol.1774 , pp. 1029-1035
    • Shibata, H.1    Kamada, H.2    Kobayashi-Nishibata, K.3    Yoshioka, Y.4    Nishibata, T.5    Abe, Y.6
  • 25
    • 0032403273 scopus 로고    scopus 로고
    • Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis
    • Reiter Y., and Pastan I. Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis. Trends Biotechnol 16 (1998) 513-520
    • (1998) Trends Biotechnol , vol.16 , pp. 513-520
    • Reiter, Y.1    Pastan, I.2
  • 26
    • 4644348208 scopus 로고    scopus 로고
    • Recombinant expression systems in the pharmaceutical industry
    • Schmidt F.R. Recombinant expression systems in the pharmaceutical industry. Appl Microbiol Biotechnol 65 (2004) 363-372
    • (2004) Appl Microbiol Biotechnol , vol.65 , pp. 363-372
    • Schmidt, F.R.1
  • 27
    • 34548646455 scopus 로고    scopus 로고
    • Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases
    • Yu P., Lee Y., Wang Y., Liu X., Auh S., Gajewski T.F., et al. Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases. J Immunol 179 (2007) 1960-1968
    • (2007) J Immunol , vol.179 , pp. 1960-1968
    • Yu, P.1    Lee, Y.2    Wang, Y.3    Liu, X.4    Auh, S.5    Gajewski, T.F.6
  • 28
    • 34347206362 scopus 로고    scopus 로고
    • Induction of potent anti-tumor immunity by direct injection of Ad-LIGHT at the site of tumor inoculation
    • Zhang J., Wang Q., Zhao D., and Cao X. Induction of potent anti-tumor immunity by direct injection of Ad-LIGHT at the site of tumor inoculation. Cytotherapy 9 (2007) 386-396
    • (2007) Cytotherapy , vol.9 , pp. 386-396
    • Zhang, J.1    Wang, Q.2    Zhao, D.3    Cao, X.4
  • 29
    • 34547865745 scopus 로고    scopus 로고
    • Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth
    • Loeffler M., Le'Negrate G., Krajewska M., and Reed J.C. Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth. Proc Natl Acad Sci USA 104 (2007) 12879-12883
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12879-12883
    • Loeffler, M.1    Le'Negrate, G.2    Krajewska, M.3    Reed, J.C.4
  • 30
    • 40849095967 scopus 로고    scopus 로고
    • Development of PEGylated adenovirus vector with targeting ligand
    • Eto Y., Yoshioka Y., Mukai Y., Okada N., and Nakagawa S. Development of PEGylated adenovirus vector with targeting ligand. Int J Pharm 354 (2008) 3-8
    • (2008) Int J Pharm , vol.354 , pp. 3-8
    • Eto, Y.1    Yoshioka, Y.2    Mukai, Y.3    Okada, N.4    Nakagawa, S.5
  • 32
    • 19944430018 scopus 로고    scopus 로고
    • Functionalization of tumor necrosis factor-α using phage display technique and PEGylation improves its antitumor therapeutic window
    • Shibata H., Yoshioka Y., Ikemizu S., Kobayashi K., Yamamoto Y., Mukai Y., et al. Functionalization of tumor necrosis factor-α using phage display technique and PEGylation improves its antitumor therapeutic window. Clin Cancer Res 10 (2004) 8293-8300
    • (2004) Clin Cancer Res , vol.10 , pp. 8293-8300
    • Shibata, H.1    Yoshioka, Y.2    Ikemizu, S.3    Kobayashi, K.4    Yamamoto, Y.5    Mukai, Y.6
  • 33
    • 38149000306 scopus 로고    scopus 로고
    • Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-α antagonist
    • Shibata H., Yoshioka Y., Ohkawa A., Minowa K., Mukai Y., Abe Y., et al. Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-α antagonist. J Biol Chem 283 (2008) 998-1007
    • (2008) J Biol Chem , vol.283 , pp. 998-1007
    • Shibata, H.1    Yoshioka, Y.2    Ohkawa, A.3    Minowa, K.4    Mukai, Y.5    Abe, Y.6
  • 34
    • 33645518464 scopus 로고    scopus 로고
    • Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis
    • Anand S., Wang P., Yoshimura K., Choi I.H., Hilliard A., Chen Y.H., et al. Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. J Clin Invest 116 (2006) 1045-1051
    • (2006) J Clin Invest , vol.116 , pp. 1045-1051
    • Anand, S.1    Wang, P.2    Yoshimura, K.3    Choi, I.H.4    Hilliard, A.5    Chen, Y.H.6
  • 35
    • 20444413440 scopus 로고    scopus 로고
    • The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease
    • Wang J., Anders R.A., Wang Y., Turner J.R., Abraham C., Pfeffer K., et al. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. J Immunol 174 (2005) 8173-8182
    • (2005) J Immunol , vol.174 , pp. 8173-8182
    • Wang, J.1    Anders, R.A.2    Wang, Y.3    Turner, J.R.4    Abraham, C.5    Pfeffer, K.6
  • 36
    • 33750348512 scopus 로고    scopus 로고
    • Targeting the lymphotoxin-β receptor with agonist antibodies as a potential cancer therapy
    • Lukashev M., LePage D., Wilson C., Bailly V., Garber E., Lukashin A., et al. Targeting the lymphotoxin-β receptor with agonist antibodies as a potential cancer therapy. Cancer Res 66 (2006) 9617-9624
    • (2006) Cancer Res , vol.66 , pp. 9617-9624
    • Lukashev, M.1    LePage, D.2    Wilson, C.3    Bailly, V.4    Garber, E.5    Lukashin, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.