Serum interferon-γ is a psoriasis severity and prognostic marker

Cutis

Volumn 84, Issue 3, 2009, Pages 163-168

  Abdallah, Marwa A ^a   Abdel Hamid, Mahmoud F ^b   Kotb, Amr M ^b   Mabrouk, Elham A ^a  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GAMMA INTERFERON;

ADULT; ARTICLE; BLOOD; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITALIZATION; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; PROGNOSIS; PSORIASIS; REMISSION; TREATMENT OUTCOME;

ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTERFERON-GAMMA; MALE; MIDDLE AGED; PROGNOSIS; PSORIASIS; REMISSION INDUCTION; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; YOUNG ADULT;

EID: 70350702961     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Nickoloff BJ, Nestle FO. Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest. 2004;113:1664-1675.
2. Liu Y, Krueger JG, Bowcock AM. Psoriasis: genetic associations and immune system changes. Genes Immun. 2007;8:1-12.
3. Prinz JC. Psoriasis vulgaris-a sterile antibacterial skin reaction mediated by crossreactive T cells? an immunological view on the pathophysiology of psoriasis. Clin Exp Dermatol. 2001;26:326-332.
4. Bonish B, Jullien D, Dutronc Y, et al. Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependant IFN-( production by NK-T cells. J Immunol. 2000;165: 4076-4085.
5. Chodorowska G. Plasma concentrations of IFN-( and TNF-a in psoriatic patients before and after local treatment with dithranol ointment. J Eur Acad Dermatol Venereol. 1998;10:147-151.
6. Szegedi A, Aleksza M, Gonda A, et al. Elevated rate of Thelper1 (T(H)1) lymphocytes and serum IFN-( levels in psoriatic patients. Immunol Lett. 2003;86:277-280.
7. Skurkovich B, Skurkovich S. IFN-( as the main target in the treatment of Th-1-mediated autoimmune skin diseases. In: Asadullah K, Volk HD, Sterry W, eds. Cytokine and Anti-Cytokine Therapy in Dermatology. Transworld Research Network: Kerala, India; 2006:261-284.
8. Skurkovich B, Skurkovich S. Autoimmune diseases are connected with disturbances in cytokine synthesis, and therapy with IFN-( blockers is their main pathogenetic treatment. Ann N Y Acad Sci. 2007;1109:167-177.
9. Fierlbeck G, Rassner G, Müller C. Psoriasis induced at the injection site of recombinant interferon gamma. results of immunohistologic investigation. Arch Dermatol. 1990;126:351-355.
10. Griffiths CE. The immunological basis of psoriasis. J Eur Acad Dermatol Venereol. 2003;17(suppl 2):1-5.
11. Koga T, Duan H, Urabe K, et al. In situ localization of IFN-(-positive cells in psoriatic lesional epidermis. Eur J Dermatol. 2002;12:20-23.
12. Oppenheim JJ, Ruscetti FW. Cytokines. In: Stites DP, Terr AI, Parslow TG, eds. Medical Immunology. 9th ed. Stamford, CT: Appleton Lange; 1997:146-168.
13. Hong K, Chu A, Lúdviksson BR, et al. IL-12, indepen- dently of IFN-(, plays a crucial role in the pathogenesis of a murine psoriasislike skin disorder. J Immunol. 1999;162:7480-7491.
14. Arican O, Aral M, Sasmaz S, et al. Serum levels of TNF-(, IFN-(, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm. 2005;2005: 273-279.
15. Jacob SE, Nassiri M, Kerdel FA, et al. Simultaneous measurement of multiple Th1 and Th2 serum cytokines in psoriasis and correlation with disease severity. Mediators Inflamm. 2003;12:309-313.
16. Piskin G, Koomen CW, Picavet D, et al. Ultraviolet-B irradiation decreases IFN-( and increases IL-4 expres-sion in psoriatic lesional skin in situ and in cultured dermal T cells derived from these lesions. Exp Dermatol. 2003;12:172-180.
17. Piskin G, Tursen U, Sylva-Steenland RM, et al. Clinical improvement in chronic plaquetype psoriasis lesions after narrowband UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers-IL-12, IL-18 and IL-23. Exp Dermatol. 2004;13: 764-772.
18. Piskin G, Heydendael VM, de Rie MA, et al. Cyclosporin A and methotrexate are equally effective in reducing T cell numbers in psoriatic skin lesions but have no consistent effect on IFN-( and IL-4 expression in psoriatic skin in situ. Arch Dermatol Res. 2003;294:559-562.