Blood gas partition coefficient and pulmonary extraction ratio for propofol in goats and pigs

Xenobiotica

Volumn 39, Issue 10, 2009, Pages 782-787

  Grossherr, M ^a   Hengstenberg, A ^b   Dibbelt, L ^a   Igl, B W ^a   Noel, R ^a   Knesebeck, A V D ^a   Schmucker, P ^a   Gehring, H ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b Research Unit   (Germany)

Author keywords

Blood gas partition coefficient; Propofol; Pulmonary extraction ratio

Indexed keywords

PROPOFOL;

ANIMAL EXPERIMENT; ARTICLE; BLOOD GAS; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL PIG; GOAT; LUNG GAS EXCHANGE; NONHUMAN; PARTITION COEFFICIENT; SPECIES DIFFERENCE;

ANESTHETICS, INTRAVENOUS; ANIMALS; BLOOD GAS ANALYSIS; EXHALATION; GOATS; LUNG; PROPOFOL; SWINE;

CAPRA HIRCUS; SUIDAE;

EID: 70350701892     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250903056109     Document Type: Article

References (26)

1. Dawidowicz A, Fornal E, Mardarowicz M, Fijalkowska A. (2000). The role of human lungs in the biotransformation of propofol. Anesthesiology 93:992-997
2. Grossherr M, Hengstenberg A, Meier T, Dibbelt L, Gerlach K, Gehring H. (2006). Discontinuous monitoring of propofol concentrations in expired alveolar gas and in arterial and venous plasma during artificial ventilation. Anesthesiology 104:786-790
3. Haagsman HP, Diemel RV. (2001). Surfactant-associated proteins: functions and structural variation. Comp Biochem Physiol A Mol Integr Physiol 91-108.
4. Hahn RG, Larsson H, Ribbe T. (1995). Continuous monitoring of irrigating fluid absorption during transurethral surgery. Anaesthesia 50: 327-331
5. Harrison GR, Critchley ADJ, Mayhew CA, Thompson JM. (2003). Realtime breath monitoring of propofol and its volatile metabolites during surgery using a novel mass spectrometric technique: a feasibility study. Br J Anaesth 91:797-799
6. He YL, Ueyama H, Tashiro C, Mashimo T, Yoshiya I. (2000). Pulmonary disposition of Propofol in surgical patients. Anesthesiology 93:986-991
7. Hengstenberg A, Grossherr M, Meier T, Dibbelt L, Gehring H. (2006). Continuous real-time monitoring of propofol in breathing gas during anesthesia. Anesthesiology A 577.
8. Hiraoka H, Yamamoto K, Miyoshi S, Morita T, Nakamura K, Kadoi Y, Kunimoto F, Horiuchi R. (2005). Kidneys contribute to the extrahepatic clearance of propofol in humans, but not lungs and brain. Br J Clin Pharmacol 60:176-182
9. Hornuss C, Praun S, Villinger J, Dornauer A, Moehnle P, Dolch M, Weninger E, Chouker A, Feil C, Briegel J, Thiel M, Schelling G. (2007). Real-time monitoring of propofol in expired air in humans undergoing total intravenous anesthesia. Anesthesiology 106:665-674
10. Jones AW. (1983). Determination of liquid /air partition coefficients for dilute solutions of ethanol in water, whole blood, and plasma. J Anal Toxicol 7:193-197
11. Jones AW, Sato A, Forsander OA. (1985). Liquid/air partition coef-ficients of acetaldehyde: values and limitations in estimating blood concentrations from analysis of breath. Alcohol Clin Exp Res 9: 461-464
12. Jones AW, Skagerberg S, Yonekura T, Sato A. (1990). Metabolic interaction between endogenous methanol and exogenous ethanol studied in human volunteers by analysis of breath. Pharmacol Toxicol 66:62-65
13. Kharasch ED. (2007). Every breath you take, we'll be watching you. Anesthesiology 106:652-654
14. Kuipers JA, Boer F, Olieman W, Burm AG, Bovill JG. (1999). First-pass lung uptake and pulmonary clearance of propofol: assessment with a recirculatory indocyanine green pharmacokinetic model. Anesthesiology 91:1780-1787
15. Kurita T, Morita K, Kazama T, Sato S. (2002). Influence of cardiac output on plasma propofol concentrations during constant infusion in swine. Anesthesiology 96:1498-1503
16. Mather LE, Selby DG, Runciman WB, McLean CF. (1989). Propofol: assay and regional mass balance in sheep. Xenobiotica 19:1337-1347
17. Matot I, Neely CF, Katz RY, Marshall BE. (1994). Fentanyl and propofol uptake by the lung: effect of time between injections. Acta Anaesthesiol Scand 38:711-715
18. Matot I, Neely CF, Katz RY, Neufeld GR. (1993). Pulmonary uptake of propofol in cats. Effect of fentanyl and halothane. Anesthesiology 78:1157-1165
19. Miekisch W, Fuchs P, Kamysek S, Neumann C, Schubert JK. (2008). Assessment of propofol concentrations in human breath and blood by means of HS-SPME-GC-MS. Clin Chim Acta 395:32-37
20. Patermann B, Buzello S, Dück M, Paul M, Kampe S. (2004). Accidental tenfold overdose of propofol in a 6-month old infant undergoing elective craniosynostosis repair. Anaesthesia 59:912-914
21. Preckel B, Schlack W. (2005). Inert gases as the future inhalational anaesthetics? Best Pract Res Clin Anaesthesiol. 19:365-379
22. Takita A, Masui K, Kazama T. (2007). On-line monitoring of end-tidal propofol concentration in anesthetized patients. Anesthesiology 106:659-664
23. Takizawa E, Ito N, Ishizeki J, Goto F, Hiraoka H, Takizawa D. (2006). The effect of positive end-expiratory pressure ventilation on propofol concentrations during general anesthesia in humans. Fundam Clin Pharmacol 20:489-492
24. Upton RN, Ludbrook GL. (1997). A physiological model of induction of anaesthesia with propofol in sheep. 1. Structure and estimation of variables. Br J Anaesth. 79:497-504.
25. Yasuda N, Lockhart SH, Eger EI II, Weiskopf RB, Johnson BH, Freire BA, Fassoulaki A. (1991a). Kinetics of desflurane, isoflurane, and halothane in humans. Anesthesiology 74:489-498
26. Yasuda N, Lockhart SH, Eger EI 2nd, Weiskopf RB, Liu J, Laster M, Taheri S, Peterson NA. (1991a). Comparison of kinetics of sevoflurane and isoflurane in humans. Anesth Analg 72:316-324