Swerilactones C and D, anti-HBV new lactones from a traditional Chinese herb: Swertia mileensis

Organic Letters

Volumn 11, Issue 21, 2009, Pages 4838-4841

  Geng, Chang An ^a,b   Zhang, Xue Mei ^a   Shen, Yong ^a,b   Zuo, Ai Xue ^a,b   Liu, Ji Feng ^a,b   Ma, Yun Bao ^a   Luo, Jie ^a   Zhou, Jun ^a   Jiang, Zhi Yong ^a   Chen, Ji Jun ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; LACTONE; SWERILACTONE C; SWERILACTONE D;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; HEPATITIS B VIRUS; HUMAN; ISOLATION AND PURIFICATION; X RAY CRYSTALLOGRAPHY;

ANTIVIRAL AGENTS; CRYSTALLOGRAPHY, X-RAY; HEPATITIS B VIRUS; HUMANS; LACTONES; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE;

EID: 70350635797     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol901881w     Document Type: Article

References (13)

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2. 8Cl calcd 423.0846).
3. 2 = 0.1487. The crystal structure of compound 1 was solved by direct method SHLXS-97 (Sheldrick, 1990) and expanded using the difference Fourier technique, refined by the program SHLXL-97 (Sheldrick, 1997), and the full-matrix least-squares calculations. Crystallographic data for the structure of compound 1 have been deposited with the Cambridge Crystallographic Data Centre (deposition no. CCDC 732831). Copies of these data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/ retrieving.htm. (or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB21EZ, U.K.; fax (+44) 1223-336-033; or desposit@ccdc. cam.ac.uk).
4. 8 calcd 387.1079).
5. 2 = 0.1000. The crystal structure of compound 2 was solved by direct method SHLXS-97 (Sheldrick, 1990) and expanded using the difference Fourier technique, refined by the program SHLXL-97 (Sheldrick, 1997), and the full-matrix least-squares calculations. Crystallographic data for the structure of compound 2 have been deposited with the Cambridge Crystallographic Data Centre (deposition no. CCDC 737797). Copies of these data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/ retrieving.htm (or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB21EZ, U.K.; fax (+44) 1223-336-033; or desposit@ccdc.cam.ac.uk).
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13. 50 = 30.5 mM, SI < 1).