Profiling the glycoforms of the intact α subunit of recombinant human chorionic gonadotropin by high-resolution capillary electrophoresis-mass spectrometry

Analytical Chemistry

Volumn 81, Issue 21, 2009, Pages 8900-8907

  Thakur, Dipak ^a   Rejtar, Tomas ^a   Karger, Barry L ^a   Washburn, Nathaniel J ^b   Bosques, Carlos J ^b   Gunay, Nur S ^b   Shriver, Zachary ^b   Venkataraman, Ganesh ^b  

^a NORTHEASTERN UNIVERSITY   (United States)

^b Momenta Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MOLECULE; CAPILLARY ELECTROPHORESIS-MASS SPECTROMETRIES; CAPILLARY ELECTROPHORETIC SEPARATIONS; CELL LINES; CHO CELL; EFFECTIVE TOOL; FAST SCAN; FOURIER TRANSFORM MASS SPECTROMETRY; GLYCAN STRUCTURES; GLYCANS; GLYCOFORMS; GLYCOPEPTIDES; GLYCOPROTEIN ANALYSIS; GLYCOSYLATED; HIGH RESOLUTION; HUMAN CHORIONIC GONADOTROPINS; IN-PROCESS MONITORING; MASS RESOLUTION; MOUSE CELL LINES; PRODUCT CHARACTERISTICS; PRODUCT CHARACTERIZATIONS; RAPID GROWTH; REPRODUCIBILITIES; SIALIC ACIDS;

ACIDS; CAPILLARY ELECTROPHORESIS; CARBOXYLIC ACIDS; ELECTROCHEMISTRY; GLUCOSE; GLYCOPROTEINS; MASS SPECTROMETERS; MASS SPECTROMETRY; PROCESS MONITORING; SEPARATION;

CELL CULTURE;

GLYCAN; GLYCOPEPTIDE; GLYCOPROTEIN; MONOSACCHARIDE; RECOMBINANT CHORIONIC GONADOTROPIN; SIALIC ACID DERIVATIVE;

ACCURACY; ANIMAL CELL; ARTICLE; CAPILLARY ELECTROPHORESIS; CARBOHYDRATE ANALYSIS; CHO CELL; FEMALE; FOURIER TRANSFORM MASS SPECTROMETRY; GLYCOSYLATION; MASS SPECTROMETRY; NONHUMAN; PROCESS MONITORING; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SEPARATION TECHNIQUE; VELOCITY;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; ELECTROPHORESIS, CAPILLARY; FOURIER ANALYSIS; GLYCOPEPTIDES; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HUMANS; MASS SPECTROMETRY; MICE; POLYSACCHARIDES; RECOMBINANT PROTEINS; TRYPSIN;

EID: 70350633790     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901506p     Document Type: Article

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