A Prospective, phase II study demonstrating the potential value and limitation of radiosurgery for spine metastases

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 32, Issue 5, 2009, Pages 515-520

  Amdur, Robert J ^a   Bennett, Jeffrey ^a   Olivier, Kenneth ^a   Wallace, Audrey ^a   Morris, Christopher G ^a   Liu, Chihray ^a   Mendenhall, William M ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Spine radiosurgery; Stereotactic body radiation therapy

Indexed keywords

ADULT; ANALGESIA; ARTICLE; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COMPRESSION FRACTURE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DYSPHAGIA; FEASIBILITY STUDY; HUMAN; NAUSEA; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN ASSESSMENT; PERCUTANEOUS VERTEBROPLASTY; PHARYNGITIS; RADIATION DOSE; RADIOSURGERY; SPINAL CORD; SPINE METASTASIS; SPINE TUMOR; STEREOTACTIC BODY RADIATION THERAPY; SYSTEMIC DISEASE; TREATMENT OUTCOME; VERTEBRA BODY;

ADULT; DISEASE-FREE SURVIVAL; FEASIBILITY STUDIES; FOLLOW-UP STUDIES; HUMANS; NEOPLASM METASTASIS; PAIN; PROSPECTIVE STUDIES; RADIOSURGERY; RADIOTHERAPY DOSAGE; SPINAL NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 70350633296     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e318194f70f     Document Type: Article

References (17)

1. Chang EL, Shiu AS, Lii MF, et al. Phase I clinical evaluation of nearsimultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys. 2004;59:1288-1294.
2. Milker-Zabel S, Zabel A, Thilmann C, et al. Clinical results of retreatment of vertebral bone metastases by stereotactic conformal radiotherapy and intensity- modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2003;55:162-167.
3. Gerszten PC, Burton SA, Welch WC, et al. Single-fraction radiosurgery for the treatment of spinal breast metastases. Cancer. 2005;104:2244-2254.
4. Gerszten PC, Ozhasoglu C, Burton SA, et al. CyberKnife frameless stereotactic radiosurgery for spinal lesions: clinical experience in 125 cases. Neurosurgery. 2004;55:89-98.
5. Ryu S, Rock J, Rosenblum M, et al. Patterns of failure after single-dose radiosurgery for spinal metastasis. J Neurosurg. 2004;101(suppl 3):402-405.
6. Ryu S, Fang YF, Rock J, et al. Image-guided and intensity-modulated radiosurgery for patients with spinal metastasis. Cancer. 2003;97:2013-2018.
7. Ryu S, Jin JY, Jin R, et al. Partial volume tolerance of the spinal cord and complications of single-dose radiosurgery. Cancer. 2007;109:628-636.
8. Wright JL, Lovelock DM, Bilsky MH, et al. Clinical outcomes after reirradiation of paraspinal tumors. Am J Clin Oncol. 2006;29:495-502.
9. Mahan SL, Ramsey CR, Scaperoth DD, et al. Evaluation of image-guided helical tomotherapy for the retreatment of spinal metastasis. Int J Radiat Oncol Biol Phys. 2005;63:1576-1583.
10. Chang EL, Shiu AS, Mendel E, et al. Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. J Neurosurg Spine. 2007;7:151-160.
11. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341-1346.
12. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
13. Frankel HL, Hancock DO, Hyslop G, et al. The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. I. Paraplegia. 1969;7:179-192.
14. McCormick PC, Torres R, Post KD, et al. Intramedullary ependymoma of the spinal cord. J Neurosurg. 1990;72:523-532.
15. Yamada Y, Bilsky MH, Lovelock DM, et al. High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions. Int J Radiat Oncol Biol Phys. 2008;71:484-490.
16. Rose CM, Kagan AR. The final report of the expert panel for the radiation oncology bone metastasis work group of the American College of Radiology. Int J Radiat Oncol Bio Physics. 1998;40:1117-1124.
17. Bone Pain Trial Working Party. 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-up. Radiother Oncol. 1999;52:111-121.