Nanolobatolide, a new C18 metabolite from the formosan soft coral sinularia nanolobata

Organic Letters

Volumn 11, Issue 21, 2009, Pages 5030-5032

  Tseng, Yen Ju ^a   Wen, Zhi Hong ^a   Dai, Chang Feng ^b   Chiang, Michael Y ^a   Sheu, Jyh Horng ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BRIDGED COMPOUND; CYCLOOXYGENASE 2 INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; NANOLOBATOLIDE; NEUROPROTECTIVE AGENT;

ANIMAL; ANTHOZOA; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; ISOLATION AND PURIFICATION; MICROGLIA; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTHOZOA; ANTI-INFLAMMATORY AGENTS; BRIDGED COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 2 INHIBITORS; MICROGLIA; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II;

EID: 70350630554     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol901990c     Document Type: Article

References (13)

1. Tseng, Y.-J.; Atallah, F. A.; Dai, C.-F.; Chiang, M. Y.; Sheu, J.-H. Org. Lett. 2005, 7, 3813-3816.
2. Chao, C.-H.; Hsieh, C.-H.; Chen, S.-P.; Lu, C.-K.; Dai, C.-F.; Wu, Y.-C.; Sheu, J.-H. Tetrahedron Lett. 2006, 47, 2175-2178.
3. Chen, S.-P.; Atallah, F. A.; Dai, C.-F.; Lu, C.-K.; Hu, W.-P.; Wang, J.-J.; Sheu, J.-H. Tetrahedron 2006, 62, 6802-6807.
4. Chao, C.-H.; Hsieh, C.-H.; Chen, S.-P.; Lu, C.-K.; Dai, C.-F.; Sheu, J.-H. Tetrahedron Lett. 2006, 47, 5889-5891.
5. Atallah, F. A.; Tai, S.-H.; Wen, Z.-H.; Su, J.-H.; Wu, Y.-C.; Hu, W.-P.; Sheu, J.-H. J. Nat. Prod. 2008, 71, 946-951.
6. Atallah, F. A.; Su, J.-H.; Shiue, R.-T.; Pan, X.-J.; Dai, G-F.; Kuo, Y.-H.; Sheu, J.-H. J. Nat. Prod. 2004,67, 592-597.
7. Crystallographic data for nanolobatolide (1) have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no.CCDC 690527. Copies of the data can be obtained, free of charage, on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, U.K. (fax: +44(0)-1223-336033 or e-mail: deposit@ccdc.cam.ac.uk).
8. Yoshiteru, O.; Tsuneo, I.; Hiroshi, H. Phytochemistry 1983, 22, 183-185.
9. Aguilar-Guadarrama, A. B.; Rios, M. Y. J. Nat. Prod. 2004, 67, 914-917.
10. Jean, Y.-H.; Chen. W.-F.; Sung, C.-S.; Duh, C.-Y.; Huang, S.-Y.; Lin, C.-S.; Tai, M.-H.; Tzeng, S.-F.; Wen, Z.-H. Br. J. Pharmacol. 2009, DOI: 10.1111/j.1476-5381.2009.00323.x.
11. Kitamura, Y.; Kosaka, T.; Kakimura, J. I.; Matsuoka, Y.; Kohno, I.; Nomura, Y.; Taniguchi, T. Mol. Pharmacol. 1998, 54, 1046-1054.
12. Blum, D.; Torch, S.; Lambeng, N.; Nissou, M.; Benabid, A. L.; Sadoul, R.; Verna, J. M. Prog. Neurobiol. 2001, 65, 135-172
13. Lee, K. Y.; Sung, S. H.; Kim, Y. C J. Nat. Prod. 2006, 69, 679-681.