Discovery and characterization of a novel lachrymatory factor synthase in Petiveria alliacea and its influence on alliinase-mediated formation of biologically active organosulfur compounds

Plant Physiology

Volumn 151, Issue 3, 2009, Pages 1294-1303

  Musah, Rabi A ^a   He, Quan ^a   Kubec, Roman ^a,b  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

PETIVERIA ALLIACEA;

EID: 70350630303     PISSN: 00320889     EISSN: 15322548     Source Type: Journal    
DOI: 10.1104/pp.109.142539     Document Type: Article

References (23)

1. Bayer T, Wagner H, Block E, Grisoni S, Zhao SH, Neszmelyi A (1989) Zwiebelanes: novel biologically active 2,3-dimethyl-5,6-dithiabicyclo[2.1.1]-hexane 5-oxides from onion. J Am Chem Soc 111: 3085-3086
2. Block E (1992) The organosulfur chemistry of the genus Allium-implications for the organic chemistry of sulfur. Angew Chem Int Ed Engl 31: 1135-1178
3. Block E (2010) Garlic and Other Alliums: The Lore and the Science. Royal Society of Chemistry, Cambridge, UK
4. Block E, Bayer T, Naganathan S, Zhao SH (1996) Allium chemistry: synthesis and sigmatropic rearrangements of alk(en)yl 1-propenyl disulfide S-oxides from cut onion and garlic. J Am Chem Soc 118: 2799-2810
5. Clark SA, Shaw ML, Every D, Lancaster JE (1998) Physical characterization of alliinase, the flavor generating enzyme in onions. J Food Biochem 22: 91-103
6. Davis B (1964) Disk electrophoresis-II method and application to human serum proteins. Ann N Y Acad Sci 121: 404-427
7. Dorsch W, Schneider E, Bayer T, Breu W, Wagner H (1990) Anti-inflammatory effects of onions: inhibition of chemotaxis of human polymorphonuclear leukocytes by thiosulfinates and cepaenes. Int Arch Allergy Appl Immunol 92: 39-42
8. Eady CC, Kamoi T, Kato M, Porter NG, Davis S, Shaw M, Kamoi A, Imai S (2008) Silencing onion lachrymatory factor synthase causes a significant change in the sulfur secondary metabolite profile. Plant Physiol 147: 2096-2106
9. Ferguson KA (1964) Starch-gel electrophoresis: application to the classification of pituitary proteins and polypeptides. Metabolism 13: 985-1002
10. Musah RA, He Q, Kubec R, Jadhav A (2009) Studies of a novel cysteine sulfoxide lyase from Petiveria alliacea: the first heteromeric alliinase. Plant Physiol 151: 1304-1316
11. Imai S, Tsuge N, Tomotake M, Nagatome Y, Sawada H, Nagata T, Kumagai H (2002) An onion enzyme that makes the eyes water. Nature 419: 685
12. Iranshahi M, Fata A, Emami B, Shahri BMJ, Bazzaz BSF (2008) In vitro antifungal activity of polysulfides-rich essential oil of Ferula latisecta fruits against human pathogenic dermatophytes. Nat Prod Commun 3: 1543-1546
13. Keusgen M (2002) Health and Alliums. In HD Rabinowitch, L Currah, eds, Allium Crop Science: Recent Advances. CAB International, Wallingford, UK, pp 357-378
14. Kim S, Kubec R, Musah RA (2006) Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L. J Ethnopharm 104: 188-192
15. Kubec R, Kim S, Musah RA (2002) S-substituted cysteine derivatives and thiosulfinate formation in Petiveria alliacea-part II. Phytochemistry 61: 675-680
16. Kubec R, Kim S, Musah RA (2003) The lachrymatory principle of Petiveria alliacea. Phytochemistry 63: 37-40
17. Kubec R, Musah RA (2001) Cysteine sulfoxide derivatives in Petiveria alliacea. Phytochemistry 58: 981-985
18. Kumagai H, Kono H, Sakurai H, Tokimoto K (2002) Comparison of C-S lyase in Lentinus edodes and Allium sativum. Biosci Biotechnol Biochem 66: 2560-2566
19. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
20. Marciani DJ, Papamatheakis JD (1978) Anomalous behavior of the major avian myeloblastosis virus glycoprotein in the presence of sodium dodecyl sulfate. J Virol 26: 825-827
21. Segrest JP, Jackson RL, Andrews EP, Marchesi VT (1971) Human erythrocyte membrane glycoprotein: a re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresis. Biochem Biophys Res Commun 44: 390-395
22. Shimon LJW, Rabinkov A, Shin I, Miron T, Mirelman D, Wilchek M, Frolow F (2007) Two structures of alliinase from Allium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor. J Mol Biol 366: 611-625
23. Simpson RJ (2004) Purifying Proteins for Proteomics: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 676