Silencing onion lachrymatory factor synthase causes a significant change in the sulfur secondary metabolite profile

Plant Physiology

Volumn 147, Issue 4, 2008, Pages 2096-2106

  Eady, Colin C ^a,b   Kamoi, Takahiro ^a   Kato, Masahiro ^c   Porter, Noel G ^b   Davis, Sheree ^b   Shaw, Martin ^b   Kamoi, Akiko ^c   Imai, Shinsuke ^c  

^a LINCOLN UNIVERSITY   (New Zealand)

^b THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED   (New Zealand)

^c House Foods Corporation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLIUM CEPA;

ALLIIN LYASE; BIS(1 PROPENYL)THIOSULFINATE; BIS(1-PROPENYL)THIOSULFINATE; LYASE; MESSENGER RNA; PROTEIN PRECURSOR; SULFINIC ACID DERIVATIVE; SULFUR; VEGETABLE PROTEIN;

ARTICLE; CHEMISTRY; ENZYMOLOGY; GENETIC TRANSFORMATION; GENETICS; METABOLISM; MOLECULAR GENETICS; ONION; PHENOTYPE; RNA INTERFERENCE; VOLATILIZATION;

CARBON-SULFUR LYASES; MOLECULAR SEQUENCE DATA; ONIONS; PHENOTYPE; PLANT PROTEINS; PROTEIN PRECURSORS; RNA INTERFERENCE; RNA, MESSENGER; SULFINIC ACIDS; SULFUR; TRANSFORMATION, GENETIC; VOLATILIZATION;

EID: 53749104163     PISSN: 00320889     EISSN: 15322548     Source Type: Journal    
DOI: 10.1104/pp.108.123273     Document Type: Article

References (49)

1. Albanese GP, Fontijne LN, inventors. June 18, 2002. Method for imparting a fried onion aroma to foodstuffs. US Patent Application No. US6,406,734 B1
2. Arnault I, Mondy N, Cadoux F, Auger J (2000) Possible interest of various sample transfer techniques for fast gas chromatography-mass spectrometric analysis of true onion volatiles. J Chromatogr A 896: 117-124
3. Arnault I, Mondy N, Diwo S, Auger J (2004) Soil behaviour of sulfur natural fumigants used as methyl bromide substitutes. Int J Environ Anal Chem 84: 75-82
4. Benavides GA, Squadrito GL, Mills RW, Patel HD, Isbell TS, Patel RP, Darley-Usmar VM, Doeller JE, Kraus DW (2007) Hydrogen sulfide mediates the vasoactivity of garlic. Proc Natl Acad Sci USA 104: 17977-17982
5. Block E (1991) The organosulfur chemistry of the onion. Phosphorus Sulfur Silicon 58: 3-15
6. Block E (1992) The organosulfur chemistry of the genus Allium: implications for organic chemistry. Angew Chem Int Ed Engl 31: 1135-1178
7. Block E, Bayer T, Naganathan S, Zhao SH (1996a) Allium chemistry: synthesis and sigmatropic rearrangements of alk(en)yl 1-propenyl disulfide S-oxides from cut onion and garlic. J Am Chem Soc 118: 2799-2810
8. Block E, Naganathan S, Putman D, Zhao SH (1992a) Allium chemistry: HPLC analysis of thiosulfinates from onion, garlic, wild garlic (ramosoms), leek, scallion, shallot, elephant (great-headed) garlic, chive, and Chinese chive. Uniquely high allyl to methyl rations in some garlic samples. J Agric Food Chem 40: 2418-2430
9. Block E, Putman D, Zhao SH (1992b) Allium chemistry: GC-MS analysis of thiosulfinates and related compounds from onion, leek, scallion, shallot, chive, and Chinese chive. J Agric Food Chem 40: 2431-2438
10. Block E, Thiruvazhi M, Toscano PJ, Bayer T, Grisoni S, Zhao SH (1996b) Allium chemistry: structure, synthesis, natural occurrence in onion (Allium cepa), and reactions of 2,3-dimethyl-5,6-dithiabicyclo[2.1.1] hexane S-oxides. J Agric Food Chem 118: 2790-2798
11. Block E, Zhao SH (1990) Onion essential oil chemistry: cis- and trans-2-mercapto-3,4-dimethyl-2,3-dihydrothiophene from pyrolysis of bis(1-propenyl) disulfide. Tetrahedron Lett 31: 4999-5002
12. Boelens M, de Valois PJ, Wobben HJ, van der Gen A (1971) Volatile flavor compounds from onion. J Agric Food Chem 19: 984-991
13. Capell T, Christou P (2004) Progress in plant metabolic engineering. Curr Opin Biotechnol 15: 148-154
14. Davuluri GR, van Tuinen A, Fraser PD, Manfredonia A, Newman R, Burgess D, Brummell DA, King SR, Palys J, Uhlig J, et al (2005) Fruit-specific RNAi-mediated suppression of DET1 enhances carotenoid and flavonoid content in tomatoes. Nat Biotechnol 23: 890-895
15. Eady C, Hunger S (2008) Alliums. In C Kole, TC Hall, eds, A Compendium of Transgenic Crop Plants. Vol 6. Vegetable Crops. Blackwell Publishing, Oxford, in press
16. Eady CC (2002) The transformation of onions and related alliums. In GG Khachotourians, ed, Transgenic Plants and Crops. Marcel Dekker, New York, pp 655-671
17. Eady CC, Truman L, McCallum J, Shaw M, Pither-Joyce M, Davis S, Reader J (2004) Transgenic onions with reduced alliinase activity: biochemical and molecular assessment. Acta Hortic 688: 181-190
18. Eady CC, Weld RJ, Lister CE (2000) Agrobacterium tumefaciens-mediated transformation and regeneration of onion (Allium cepa L.). Plant Cell Rep 19: 376-381
19. Fritsch RM, Keusgen M (2006) Occurrence and taxonomic significance of cysteine sulphoxides in the genus Allium L. (Alliaceae). Phytochemistry 67: 1127-1135
20. Gleave AP (1992) Aversatile binary vector system with a T-DNA organisational structure conductive to efficient integration of cloned DNA into the plant genome. Plant Mol Biol 20: 1203-1207
21. Griffiths G, Trueman L, Crowther T, Thomas B, Smith B (2002) Onions: a global benefit to health. Phytother Res 16: 603-615
22. Hamilton AJ, Baulcombe DC (1999) A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286: 950-952
23. Haseloff J, Siemering KR, Prasher DC, Hodge S (1997) Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly. Proc Natl Acad Sci USA 94: 2122-2127
24. Hiramitsu T, inventor. May 10, 1989. Novel 1-propenethiol derivative and process for preparing. Japanese Patent Application No. JP01,117,856 [89,117,856] (CI. C07C149/00)
25. Hori M (2007) Onion aphid (Neotoxoptera formosana) attractants, in the headspace of Allium fistulosum and A. tuberosum leaves. J Appl Entomol 131: 8-12
26. Imai S, Akita K, Tomotake M, Sawada H (2006a) Identification of two novel pigment precursors and a reddish-purple pigment involved in the bluegreen discoloration of onion and garlic. J Agric Food Chem 54: 843-847
27. Imai S, Akita K, Tomotake M, Sawada H (2006b) Model studies on precursor system generating blue pigment in onion and garlic. J Agric Food Chem 54: 848-852
28. Imai S, Tsuge N, Tomotake M, Nagatome Y, Sawada H, Nagata T, Kumagai H (2002) Plant biochemistry: an onion enzyme that makes the eyes water. Nature 419: 685
29. Keusgen M (2002) Health and alliums. In HD Rabinowitch, L Currah, eds, Allium Crop Science: Recent Advances. CAB International, Wallingford, UK, pp 357-378
30. Kitamura N, Shimomura N, Iseki J, Honma M, Shiba S, Tahara S, Mizutani J (1997) Cysteine-S-conjugate β-lyase activity and pyridoxial phosphate binding site of onion alliin lyase. Biosci Biotechnol Biochem 61: 1327-1330
31. Kopsel DE, Randle WM (1999) Changes in the S-alk(en)yl cysteine sulfoxides and their biosynthetic intermediates during onion storage. J Am Soc Hortic Sci 124: 177-183
32. Kuo MC, Ho CT (1992a) Volatile constituents of the distilled oils of Welsh onions (Allium fistulosum L. variety maichuon) and scallions (Allium fistulosum L. variety caespitosum). J Agric Food Chem 40: 111-117
33. Kuo MC, Ho CT (1992b) Volatile constituents of the solvent extracts of Welsh onions (Allium fistulosum L. variety maichuon) and scallions (Allium fistulosum L. variety caespitosum). J Agric Food Chem 40: 1906-1910
34. Lancaster JE, Boland MJ (1990) Flavor biochemistry. In JL Brewster, HD Rabinowich, eds, Onions and Allied Crops, Vol. 3. CRC Press, Boca Raton, FL, pp 33-72
35. Lancaster JE, Shaw ML, Pither-Joyce MD, McCallum J, McManus MT (2000) A novel alliinase from onion roots: biochemical analysis and cDNA cloning. Plant Physiol 122: 1269-1279
36. Lanzotti V (2006) The analysis of onion and garlic. J Chromatogr A 1112: 3-22
37. Lee CH, Parkin KL (1998) Relationship between thiosulfinates and pink discoloration in onion extracts, as influenced by pH. Food Chem 61: 345-350
38. Lefer DJ (2007) A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide. Proc Natl Acad Sci USA 104: 17907-17908
39. McCallum J, Porter N, Searle B, Shaw M, Bettjeman B, McManus M (2005) Sulfur and nitrogen affects flavour of field-grown onions. Plant Soil 269: 151-158
40. Morimitsu Y, Morioka Y, Kawakishi S (1992) Inhibitors of platelet aggregation generated from mixtures of Allium species and/or S-alk(en)nyl-L-cysteine sulfoxides. J Agric Food Chem 40: 368-372
41. Muskens MW, Vissers AP, Mol JN, Kooter JM (2000) Role of inverted DNA repeats in transcriptional and post-transcriptional gene silencing. Plant Mol Biol 43: 243-260
42. Randle WM (1997) Onion flavor chemistry and factors influencing flavor intensity. In SJ Risch, C Ho, eds, Spices: Flavor Chemistry and Antioxidant Properties. American Chemical Society, Washington, DC, pp 41-52
43. Randle WM, Lancaster JE (2002) Sulphur compounds in alliums. In HD Rabinowitch, L Currah, eds, Allium Crop Science: Recent Advances. CAB International, Wallingford, UK, pp 329-356
44. Randle WM, Lancaster JE, Shaw ML, Sutton KH, Hay RL, Bussard ML (1995) Quantifying onion flavor compounds responding to sulfur fertility: sulfur increases levels of alk(en)yl cysteine sulfoxides and biosynthetic intermediates. J Am Soc Hortic Sci 120: 1075-1081
45. Rose P, Whiteman M, Moore PK, Zhu YZ (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Nat Prod Rep 22: 351-368
46. Sinha KN, Guyer ED, Gage AD, Lira TC (1992) Supercritical carbon dioxide extraction of onion flavors and their analysis by gas chromatography-mass spectrometry. J Agric Food Chem 40: 842-845
47. Sunilkumar G, Campbell LM, Puckhaber L, Stipanovic RD, Rathore KS (2006) Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol. Proc Natl Acad Sci USA 103: 18054-18059
48. Tang W, Newton RJ, Weidner DA (2007) Genetic transformation and gene silencing mediated by multiple copies of a transgene in eastern white pine. J Exp Bot 58: 545-554
49. Wesley SV, Helliwell CA, Smith NA, Wang M, Rouse DT, Liu Q, Gooding PS, Singh SP, Abbott D, Stoutjesdijk PA, et al (2001) Construct design for efficient, effective and high-throughput gene silencing in plants. Plant J 27: 581-590