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Volumn 11, Issue 21, 2009, Pages 5074-5077

Expeditious synthesis of vialinin B, an extremely potent inhibitor of TNF-aα production

Author keywords

[No Author keywords available]

Indexed keywords

BENZOFURAN DERIVATIVE; PHENYLACETIC ACID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; VIALININ B;

EID: 70350625335     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol9020833     Document Type: Article
Times cited : (44)

References (33)
  • 4
  • 5
    • 0032518829 scopus 로고    scopus 로고
    • For recent review, see: (a) Stanforth, S. P. Tetrahedron 1998, 54, 263-303.
    • (1998) Tetrahedron , vol.54 , pp. 263-303
    • Stanforth, S.P.1
  • 8
    • 50249094327 scopus 로고    scopus 로고
    • and references cited therein
    • (d) Manabe, K.; Ishikawa, S. Chem. Commun. 2008, 382, 3829-3838, and references cited therein.
    • (2008) Chem. Commun. , vol.382 , pp. 3829-3838
    • Manabe, K.1    Ishikawa, S.2
  • 9
    • 67749102055 scopus 로고    scopus 로고
    • For recent syntheses of simple benzofuran derivatives without polyoxy functions, see: (a) Wang, G; Piel, L; Glorius, F. J. Am. Chem. Soc. 2009, 131, 4194-4195.
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 4194-4195
    • Wang, G.1    Piel, L.2    Glorius, F.3
  • 15
    • 70350694029 scopus 로고    scopus 로고
    • 3B, THF, -78 to O °C (97%); see the Supporting Information
    • 3B, THF, -78 to O °C (97%); see the Supporting Information.
  • 17
    • 70350653545 scopus 로고    scopus 로고
    • Although several spots were observed on TLC, a double coupling product could not be isolated
    • Although several spots were observed on TLC, a double coupling product could not be isolated.
  • 18
    • 70350694030 scopus 로고    scopus 로고
    • 1H NMR spectra of 9 and 10, the up-field shift of the formyl proton due to the shielding effect of the neighboring aromatic ring was observed
    • 1H NMR spectra of 9 and 10, the up-field shift of the formyl proton due to the shielding effect of the neighboring aromatic ring was observed.
  • 26
    • 70350671248 scopus 로고    scopus 로고
    • No presence of potassium fluoride decreased the yield of 15
    • No presence of potassium fluoride decreased the yield of 15.
  • 30
    • 70350678538 scopus 로고    scopus 로고
    • LTA oxidation of 5,6-bis(methoxymethoxy)benzo[d][l,3]dioxole as a model compound gave the corresponding orthoester in high yield
    • LTA oxidation of 5,6-bis(methoxymethoxy)benzo[d][l,3]dioxole as a model compound gave the corresponding orthoester in high yield.
  • 31
    • 70350694027 scopus 로고    scopus 로고
    • 13C NMR data (δ 119.83 for C-9b) of 1 denoted in ref 1 was a typographical errror and should be revised to 119.38 ppm
    • 13C NMR data (δ 119.83 for C-9b) of 1 denoted in ref 1 was a typographical errror and should be revised to 119.38 ppm.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.