Development and validation of a stability-indicating RP-HPLC method for assay of betamethasone and estimation of its related compounds

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 3, 2010, Pages 617-625

  Fu, Qiang ^a   Shou, Minshan ^a   Chien, Dwight ^a   Markovich, Robert ^a   Rustum, Abu M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

1,2 Dihydrobetamethasone; Betamethasone; Betamethasone 21 aldehyde; Dexamethasone; Stability indicating HPLC method

Indexed keywords

1,2 DIHYDROBETAMETHASONE; BETAMETHASONE; BETAMETHASONE 21 ALDEHYDE; BETAMETHASONE DERIVATIVE; DEXAMETHASONE; DIOXANE; MESYLIC ACID; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG;

ACCURACY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; ELUTION; FLOW RATE; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

BETAMETHASONE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE;

EID: 70350616190     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.09.034     Document Type: Article

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