Prevalence and clinical features of heterozygous carriers of autosomal recessive hypercholesterolemia in Sardinia

Atherosclerosis

Volumn 207, Issue 1, 2009, Pages 162-167

  Filigheddu, Fabiana ^a   Quagliarini, Fabiana ^b   Campagna, Filomena ^b   Secci, Tanuccia ^a   Degortes, Simona ^a   Zaninello, Roberta ^a   Argiolas, Giuseppe ^a   Verna, Roberto ^b   Pitzoi, Silvia ^a   Frau, Francesca ^a   Troffa, Chiara ^a   Bulla, Emanuela ^a   Bertolini, Stefano ^c   Glorioso, Nicola ^a   Arca, Marcello ^b  

^a UNIVERSITY OF SASSARI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Autosomal recessive hypercholesterolemia; Clinical phenotype; Genetic hypercholesterolemia; Heterozygous carriers; Myocardial infarction risk

Indexed keywords

AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA 1 PROTEIN; AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA 2 PROTEIN; GENE PRODUCT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BLOOD DONOR; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; GENE FREQUENCY; HEART INFARCTION; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HYPERTENSION; ITALY; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; PREVALENCE; PRIORITY JOURNAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHOLESTEROL, LDL; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; HYPERCHOLESTEROLEMIA; ITALY; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; ODDS RATIO; PHENOTYPE; PREVALENCE; RISK ASSESSMENT; RISK FACTORS;

EID: 70350575332     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.04.027     Document Type: Article

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