Lack of prognostic significance of the germinal-center phenotype in diffuse large B-cell lymphoma patients treated with CHOP-like chemotherapy with and without rituximab

International Journal of Hematology

Volumn 90, Issue 1, 2009, Pages 74-80

  Ilić, Ivana ^a   Mitrović, Zdravko ^a   Aurer, Igor ^a   Bašić Kinda, Sandra ^a   Radman, Ivo ^a   Ajduković, Radmila ^b   Labar, Boris ^a   Dotlić, Snježana ^a   Nola, Marin ^a  

^a KBC Zagreb   (Croatia)

^b University of Zagreb School of Medicine   (Croatia)

Author keywords

CHOP chemotherapy; Immunohistochemistry; Lymphoma, large B cell, diffuse; Lymphoma, non Hodgkin; Rituximab

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISONE; RITUXIMAB; VINCRISTINE;

ARTICLE; B CELL LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; EVENT FREE SURVIVAL; GERMINAL CENTER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; PHENOTYPE; PROGNOSIS; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; GERMINAL CENTER; HUMANS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 70350567218     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-009-0353-y     Document Type: Article

References (23)

1. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, editors. WHO Classification of tumours of haematopoietic and lymphoid tissues. IARC: Lyon 2008.
2. B Coiffier 2001 Diffuse large cell lymphoma Curr Opin Oncol 13 325 334 10.1097/00001622-200109000-00003 11555708 10.1097/00001622-200109000-00003 1:STN:280:DC%2BD3Mrgs1Sgtw%3D%3D (Pubitemid 32783410)
3. M Pfreundschuh L Trumper A Osterborg R Rettengell M Trneny K Imrie, et al. 2006 CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B cell lymphoma: a randomized controlled trial by the MabThera International Trial (MInT) Group Lancet Oncol 7 379 391 10.1016/S1470-2045(06)70664-7 16648042 10.1016/S1470-2045(06)70664-7 1:CAS:528:DC%2BD28XjvFWlsbw%3D
4. P Feugier A Van Hoof C Sebban P Solal-Celigny R Bouabdallah C Ferme, et al. 2005 Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte J Clin Oncol 23 4117 4126 10.1200/JCO.2005.09.131 15867204 10.1200/JCO.2005.09.131 1:CAS:528:DC%2BD2MXmt1elsr0%3D (Pubitemid 46211317)
5. P De Paepe C De Wolf-Peeters 2007 Diffuse large B-cell lymphoma: a heterogeneous group of non-Hodgkin lymphomas comprising several distinct clinicopathological entities Leukemia 21 37 43 10.1038/sj.leu.2404449 17039226 10.1038/sj.leu.2404449 (Pubitemid 44921832)
6. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med. 1993;329:987-94. doi: 10.1056/NEJM199309303291402.
7. AA Alizadeh MB Eisen RE Davis C Ma IS Lossos A Rosenwald, et al. 2000 Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling Nature 403 503 511 10.1038/35000501 10676951 10.1038/35000501 1:CAS:528:DC%2BD3cXht1Shtrg%3D (Pubitemid 30082188)
8. MA Shipp KN Ross P Tamayo AP Weng JL Kutok RC Aguiar, et al. 2002 Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning Nat Med 8 68 74 10.1038/nm0102-68 11786909 10.1038/nm0102-68 1:CAS:528:DC%2BD38XjtlygsQ%3D%3D (Pubitemid 34101731)
9. A Rosenwald LM Staudt 2003 Gene expression profiling of diffuse large B-cell lymphoma Leuk Lymphoma 443 Suppl 1 S41 S47 10.1080/10428190310001623775 (Pubitemid 38196062)
10. IS Lossos DK Czerwinski AA Alizadeh MA Wechser R Tibshirani D Botstein, et al. 2004 Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes N Engl J Med 350 1828 1837 10.1056/NEJMoa032520 15115829 10.1056/NEJMoa032520 1:CAS:528:DC%2BD2cXjsVOhtb0%3D (Pubitemid 38917249)
11. CP Hans DD Weisenburger TC Greiner RD Gascoyne J Delabie G Ott, et al. 2004 Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray Blood 103 275 282 10.1182/blood-2003-05-1545 14504078 10.1182/blood-2003-05-1545 1:CAS:528:DC%2BD2cXhsFGhsA%3D%3D (Pubitemid 38029949)
12. M Berglund U Thunberg RM Amini M Book G Roos M Erlanson, et al. 2005 Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis Mod Pathol 18 1113 1120 10.1038/modpathol.3800396 15920553 10.1038/modpathol.3800396 1:CAS:528:DC%2BD2MXmtlCrsrw%3D (Pubitemid 41224503)
13. GW Van Imhoff EJ Boerma B van der Holt E Schuuring LF Verdonck HC Kluin-Nelemans, et al. 2006 Prognostic impact of germinal center-associated proteins and chromosomal breakpoints in poor-risk diffuse large B-cell lymphoma J Clin Oncol 24 4135 4142 10.1200/JCO.2006.05.5897 16943530 10.1200/JCO.2006.05. 5897 (Pubitemid 46622290)
14. YH Oh CK Park 2006 Prognostic evaluation of nodal diffuse large B cell lymphoma by immunohistochemical profiles with emphasis on CD138 expression as a poor prognostic factor J Korean Med Sci 21 397 405 10.3346/jkms.2006.21.3.397 16778379 10.3346/jkms.2006.21.3.397 1:CAS:528:DC%2BD28XnslSjt7s%3D
15. LD Sjö CB Poulsen M Hansen MB Møller E Ralfkiaer 2007 Profiling of diffuse large B-cell lymphoma by immunohistochemistry: identification of prognostic subgroups Eur J Haematol 79 501 507 10.1111/j.1600-0609.2007.00976.x 17986209 10.1111/j.1600-0609.2007.00976.x (Pubitemid 350126679)
16. H Nyman M Adde ML Karjalainen-Lindsberg M Taskinen M Berglund RM Amini, et al. 2007 Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy Blood. 109 4930 4935 10.1182/blood-2006-09-047068 17299093 10.1182/blood-2006-09-047068 1:CAS:528:DC%2BD2sXmt1Ogu7Y%3D (Pubitemid 46827791)
17. CH Moskowitz AD Zelenetz T Kewalramani P Hamlin S Lessac-Chenen J Houldsworth, et al. 2005 Cell of origin, germinal center versus nongerminal center, determined by immunochistochemistry on tissue microarray, does not correlate with outcome in patients with relapsed and refractory DLBCL Blood. 106 3383 3385 10.1182/blood-2005-04-1603 16091454 10.1182/blood-2005-04-1603 1:CAS:528:DC%2BD2MXht1ehsb%2FN (Pubitemid 41609171)
18. L Colomo A Lopez-Guillermo M Perales S Rives A Martinez F Bosch, et al. 2003 Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma Blood 101 78 84 10.1182/blood-2002-04-1286 12393466 10.1182/blood-2002-04-1286 1:CAS:528:DC%2BD3sXhtFSqtw%3D%3D (Pubitemid 36025890)
19. H Veelken S Vik Dannheim J Schulte Moenting UM Martens J Finke A Schmitt-Graeff 2007 Immunophenotype as prognostic factor for diffuse large B-cell lymphoma in patients undergoing clinical risk-adapted therapy Ann Oncol 18 931 939 10.1093/annonc/mdm012 17395602 10.1093/annonc/mdm012 1:STN:280:DC%2BD2s3ns12luw%3D%3D (Pubitemid 47054092)
20. BD Cheson SJ Horning B Coiffier MA Shipp RI Fisher JM Connors, et al. 1999 Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group J Clin Oncol 17 1244 1253 10561185 1:STN:280:DC%2BD3c%2FivF2itg%3D%3D
21. K Fu DD Weisenburger WWL Choi KD Perry LM Smith X Shi, et al. 2008 Addition of rituximab to standard chemotherapy improves the survival of both the germinal center B-cell-like and non-germinal center B-cell-like subtypes of diffuse large B-cell lymphoma J Clin Oncol 26 4587 4594 10.1200/JCO.2007.15.9277 18662967 10.1200/JCO.2007.15.9277 1:CAS:528:DC%2BD1cXht1KqtLfI
22. SC Peh GG Gan LK Lee GI Eow 2008 Clinical relevance of CD10, BCL-6 and multiple myeloma-1 expression in diffuse large B-cell lymphomas in Malaysia Pathol Int 58 572 579 18801072 10.1111/j.1440-1827.2008.02273.x
23. B Fabiani A Delmer E Lepage C Guettier T Petrella J Brière AM Penny MC Copin J Diebold F Reyes P Gaulard TJ Molina 2004 Groupe d'Etudes des Lymphomes de l'Adulte. CD10 expression in diffuse large B-cell lymphomas does not influence survival Virchows Arch 445 545 551 10.1007/s00428-004-1129-7 15517363 10.1007/s00428-004-1129-7 1:CAS:528:DC%2BD2cXhtVensrzK (Pubitemid 40104529)