메뉴 건너뛰기




Volumn 156, Issue 12, 1996, Pages 4739-4745

Induction of Th1 cell-mediated protective immunity to Schistosoma mansoni by co-administration of larval antigens and IL-12 as an adjuvant

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 4; SCHISTOSOMA VACCINE;

EID: 0029882942     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (87)

References (52)
  • 2
    • 0026060650 scopus 로고
    • Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
    • Pearce, E. J., P. Caspar, J-M. Gryzch, F. A. Lewis, and A. Sher. 1991. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 173:159.
    • (1991) J. Exp. Med. , vol.173 , pp. 159
    • Pearce, E.J.1    Caspar, P.2    Gryzch, J.-M.3    Lewis, F.A.4    Sher, A.5
  • 3
    • 0025924547 scopus 로고
    • Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni
    • Gryzch, J-M., E. Pearce, A. Cheever, Z. A. Caulada, P. Caspar, S. Hieny, F. Lewis, and A. Sher. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni. J. Immunol. 146: 1322.
    • (1991) J. Immunol. , vol.146 , pp. 1322
    • Gryzch, J.-M.1    Pearce, E.2    Cheever, A.3    Caulada, Z.A.4    Caspar, P.5    Hieny, S.6    Lewis, F.7    Sher, A.8
  • 4
    • 0028113161 scopus 로고
    • The profile of IgG1 and IgG2a responses in mice exposed to Schistosoma mansoni
    • Mountford, A. P., A. Fisher, and R. A. Wilson. 1994. The profile of IgG1 and IgG2a responses in mice exposed to Schistosoma mansoni. Parasite Immunol. 16:521.
    • (1994) Parasite Immunol. , vol.16 , pp. 521
    • Mountford, A.P.1    Fisher, A.2    Wilson, R.A.3
  • 5
    • 0025149043 scopus 로고
    • Leaky livers, portal shunting and immunity to schistosomes
    • Wilson, R. A. 1990. Leaky livers, portal shunting and immunity to schistosomes. Parasitol. Today 6:354.
    • (1990) Parasitol. Today , vol.6 , pp. 354
    • Wilson, R.A.1
  • 6
    • 0023813428 scopus 로고
    • Antigen localisation and the induction of resistance in mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Mountford, A. P., P. S. Coulson, and R. A. Wilson. 1988. Antigen localisation and the induction of resistance in mice vaccinated with irradiated cercariae of Schistosoma mansoni. Parasitology 97:11.
    • (1988) Parasitology , vol.97 , pp. 11
    • Mountford, A.P.1    Coulson, P.S.2    Wilson, R.A.3
  • 7
    • 0024462786 scopus 로고
    • Fate of attenuated schistosomula administered by different routes, relative to the immunity induced against Schistosoma mansoni
    • Coulson, P. S., and A. P. Mountford. 1989. Fate of attenuated schistosomula administered by different routes, relative to the immunity induced against Schistosoma mansoni. Parasitology 99:39.
    • (1989) Parasitology , vol.99 , pp. 39
    • Coulson, P.S.1    Mountford, A.P.2
  • 8
    • 0025125389 scopus 로고
    • Phenotypic analysis of the cellular responses in the regional lymphoid organs of mice vaccinated against Schistosoma mansoni
    • Constant, S. L., A. P. Mountford, and R. A. Wilson. 1990. Phenotypic analysis of the cellular responses in the regional lymphoid organs of mice vaccinated against Schistosoma mansoni. Parasitology 101:15.
    • (1990) Parasitology , vol.101 , pp. 15
    • Constant, S.L.1    Mountford, A.P.2    Wilson, R.A.3
  • 10
    • 0026708718 scopus 로고
    • Regulation of immunity to parasites by Tcells and T cell-derived cytokines Annu
    • Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by Tcells and T cell-derived cytokines Annu. Rev. Immunol. 10:385.
    • (1992) Rev. Immunol. , vol.10 , pp. 385
    • Sher, A.1    Coffman, R.L.2
  • 11
    • 0025765572 scopus 로고
    • Patterns of cytokine production and proliferation by T lymphocytes differ in mice vaccinated or infected with Schistosoma mansoni
    • Pemberton, R. M., L. E. Smythies, A. P. Mountford, and R. A. Wilson. 1991. Patterns of cytokine production and proliferation by T lymphocytes differ in mice vaccinated or infected with Schistosoma mansoni. Immunology 73:327.
    • (1991) Immunology , vol.73 , pp. 327
    • Pemberton, R.M.1    Smythies, L.E.2    Mountford, A.P.3    Wilson, R.A.4
  • 12
    • 0026550253 scopus 로고
    • The generation of interferon-gamma-secreting T lymphocytes in the skin-draining lymph nodes and their recruitment to the lungs is associated with protective immunity to Schistosoma mansoni
    • Mountford, A. P., P. S. Coulson, R. M. Pemberton, L. E. Smythies, and R. A. Wilson. 1992. The generation of interferon-gamma-secreting T lymphocytes in the skin-draining lymph nodes and their recruitment to the lungs is associated with protective immunity to Schistosoma mansoni. Immunology 75:250.
    • (1992) Immunology , vol.75 , pp. 250
    • Mountford, A.P.1    Coulson, P.S.2    Pemberton, R.M.3    Smythies, L.E.4    Wilson, R.A.5
  • 13
    • 0026595061 scopus 로고
    • T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Smythies, L. E., R. M. Pemberton, P. S. Coulson, A. P. Mountford, and R. A. Wilson. 1992. T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni. J. Immunol. 148:1512.
    • (1992) J. Immunol. , vol.148 , pp. 1512
    • Smythies, L.E.1    Pemberton, R.M.2    Coulson, P.S.3    Mountford, A.P.4    Wilson, R.A.5
  • 14
    • 0024363962 scopus 로고
    • Lung-phase immunity to schistosomes: A new perspective to an old problem
    • Wilson, R. A., and P. S. Coulson. 1989. Lung-phase immunity to schistosomes: a new perspective to an old problem. Parasitol. Today 5:274.
    • (1989) Parasitol. Today , vol.5 , pp. 274
    • Wilson, R.A.1    Coulson, P.S.2
  • 15
    • 0027492979 scopus 로고
    • Pulmonary granulomatous hypersensitivity: Cell-mediated responses to embolized schistosome larvae and eggs
    • Coulson, P. S., L. E. Smythies, and R. A. Wilson. 1993. Pulmonary granulomatous hypersensitivity: cell-mediated responses to embolized schistosome larvae and eggs. Reg. Immunol. 5:165.
    • (1993) Reg. Immunol. , vol.5 , pp. 165
    • Coulson, P.S.1    Smythies, L.E.2    Wilson, R.A.3
  • 16
    • 0026452253 scopus 로고
    • Monoclonal antibody to IFN-γ modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice previously vaccinated with attenuated cercariae
    • Smythies, L. E., P. S. Coulson, and R. A. Wilson. 1992. Monoclonal antibody to IFN-γ modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice previously vaccinated with attenuated cercariae. J. Immunol. 149:3654.
    • (1992) J. Immunol. , vol.149 , pp. 3654
    • Smythies, L.E.1    Coulson, P.S.2    Wilson, R.A.3
  • 17
    • 0026616876 scopus 로고
    • Induction of Th1 and Th2 responses: A key role for the natural immune response?
    • Romagnani, S. 1992. Induction of Th1 and Th2 responses: a key role for the natural immune response? Immunol. Today 13:379.
    • (1992) Immunol. Today , vol.13 , pp. 379
    • Romagnani, S.1
  • 18
    • 0028361047 scopus 로고
    • Role of cytokines in determining T lymphocyte function
    • O'Garra, A., and K. Murphy. 1994. Role of cytokines in determining T lymphocyte function. Curr. Opin. Immunol. 6:458.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 458
    • O'Garra, A.1    Murphy, K.2
  • 20
    • 0028281585 scopus 로고
    • Interleukin 12: A key modulator of immune function
    • Wolf, S. F., D. Sieburth, and J. Sypeck. 1994. Interleukin 12: a key modulator of immune function. Stem Cells 12:154.
    • (1994) Stem Cells , vol.12 , pp. 154
    • Wolf, S.F.1    Sieburth, D.2    Sypeck, J.3
  • 21
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251
    • Trinchieri, G.1
  • 24
    • 0025819340 scopus 로고
    • Induction of interferon γ production by natural killer cell stimulatory factor: Characterisation of the responder cells and synergy with other inducers
    • Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Posuisil, H. A. Young, S. F. Wolf, D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon γ production by natural killer cell stimulatory factor: characterisation of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
    • (1991) J. Exp. Med. , vol.173 , pp. 869
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Posuisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 25
    • 0027530129 scopus 로고
    • Interleukin 12 and tumor necrosis factor a are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist
    • Tripp, C. S., S. F. Wolf, and E. L. Unanue. 1993. Interleukin 12 and tumor necrosis factor a are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 90:3725.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3725
    • Tripp, C.S.1    Wolf, S.F.2    Unanue, E.L.3
  • 27
    • 0027491655 scopus 로고
    • + T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming
    • + T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90:10188.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10188
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 28
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte-independenl induction of interferon γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R. T., S. Hieny, T. A. Wynn, S. Wolf, and A. Sher. 1993. Interleukin 12 is required for the T-lymphocyte-independenl induction of interferon γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA 90:6115.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 29
    • 0028950126 scopus 로고
    • Interleukin 12 is effective treatment for an established systematic intracellular infection: Experimental visceral leishmaniasis
    • Murray, H. W., and J. Hariprashad. 1995. Interleukin 12 is effective treatment for an established systematic intracellular infection: experimental visceral leishmaniasis. J. Exp. Med. 181:387.
    • (1995) J. Exp. Med. , vol.181 , pp. 387
    • Murray, H.W.1    Hariprashad, J.2
  • 33
    • 0029038859 scopus 로고
    • IL-12 modulation of T helper responses to the filarial helminth, Brugia malayi
    • Pearlman, E., F. P. Heinzel, F. E. Hazlett Jr, and J. W. Kazura. 1995. IL-12 modulation of T helper responses to the filarial helminth, Brugia malayi. J. Immunol. 154:4658.
    • (1995) J. Immunol. , vol.154 , pp. 4658
    • Pearlman, E.1    Heinzel, F.P.2    Hazlett Jr., F.E.3    Kazura, J.W.4
  • 34
    • 0028231754 scopus 로고
    • Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • Wynn, T. A., I. Eltoum, I. P. Oswald, A. W. Cheever, and A. Sher. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551.
    • (1994) J. Exp. Med. , vol.179 , pp. 1551
    • Wynn, T.A.1    Eltoum, I.2    Oswald, I.P.3    Cheever, A.W.4    Sher, A.5
  • 36
    • 0028967643 scopus 로고
    • Antigens derived from lung-stage larvae of Schistosoma mansoni are efficient stimulators of proliferation and gamma interferon secretion by lymphocytes from mice vaccinated with attenuated larvae
    • Mountford, A. P., R. Harrop, and R. A. Wilson. 1995. Antigens derived from lung-stage larvae of Schistosoma mansoni are efficient stimulators of proliferation and gamma interferon secretion by lymphocytes from mice vaccinated with attenuated larvae. Infect. Immun. 63:1980.
    • (1995) Infect. Immun. , vol.63 , pp. 1980
    • Mountford, A.P.1    Harrop, R.2    Wilson, R.A.3
  • 37
    • 0027280121 scopus 로고
    • Protein synthesis and release by cultured schistosomula of Schistosoma mansoni
    • Harrop, R., and R. A. Wilson. 1993. Protein synthesis and release by cultured schistosomula of Schistosoma mansoni. Parasitology 107:265.
    • (1993) Parasitology , vol.107 , pp. 265
    • Harrop, R.1    Wilson, R.A.2
  • 38
    • 0028957941 scopus 로고
    • T-helper type 1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are downregulated after challenge infection
    • Pemberton, R. M., and R. A. Wilson. 1995. T-helper type 1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are downregulated after challenge infection. Immunology 83:310.
    • (1995) Immunology , vol.83 , pp. 310
    • Pemberton, R.M.1    Wilson, R.A.2
  • 39
    • 0027282771 scopus 로고
    • - effector/memory cells in mice vaccinated with attenuated cercariae of Schistosoma mansoni
    • - effector/memory cells in mice vaccinated with attenuated cercariae of Schistosoma mansoni. J. Immunol. 151:3663.
    • (1993) J. Immunol. , vol.151 , pp. 3663
    • Coulson, P.S.1    Wilson, R.A.2
  • 40
    • 0028329177 scopus 로고
    • Effects of IL-12 on helper T cell-dependent immune responses in vivo
    • McKnight, A. J., G. J. Zimmer, I. Fogelman, S. F. Wolf, and A. K. Abbas. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152:2172.
    • (1994) J. Immunol. , vol.152 , pp. 2172
    • McKnight, A.J.1    Zimmer, G.J.2    Fogelman, I.3    Wolf, S.F.4    Abbas, A.K.5
  • 42
    • 0028947010 scopus 로고
    • The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection
    • Cooper, A. M., A. D. Roberts, E. R. Rhoades, Callahan, D. M. Getzy, and I. M. Orme. 1995. The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection. Immunology 84:423.
    • (1995) Immunology , vol.84 , pp. 423
    • Cooper, A.M.1    Roberts, A.D.2    Rhoades, E.R.3    Callahan4    Getzy, D.M.5    Orme, I.M.6
  • 43
    • 0029042649 scopus 로고
    • IL-12 enhances vaccine-immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production and tissue eosinophilia
    • Wynn, T. A. D. Jankovic, S. Hieny, A. W. Cheever, and A. Sher. 1995. IL-12 enhances vaccine-immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production and tissue eosinophilia. J. Immunol. 154:4701.
    • (1995) J. Immunol. , vol.154 , pp. 4701
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Cheever, A.W.4    Sher, A.5
  • 44
    • 0028931469 scopus 로고
    • IL-12 exacerbates rather than suppresses Th2-dependent pathology in the absence of endogenous IFN-γ
    • Wynn, T. A., D. Jankovic, S. Hieny, K. Zioncheck, P. Jardieu, A. W. Cheever, and A. Sher. 1995. IL-12 exacerbates rather than suppresses Th2-dependent pathology in the absence of endogenous IFN-γ. J. Immunol. 154:3999.
    • (1995) J. Immunol. , vol.154 , pp. 3999
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Zioncheck, K.4    Jardieu, P.5    Cheever, A.W.6    Sher, A.7
  • 45
    • 0028069831 scopus 로고
    • IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni
    • Oswald, I. P., P. Caspar, D. Jankovic, T. A. Wynn, E. J. Pearce, and A. Sher. 1994. IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni. J. Immunol. 153:1707.
    • (1994) J. Immunol. , vol.153 , pp. 1707
    • Oswald, I.P.1    Caspar, P.2    Jankovic, D.3    Wynn, T.A.4    Pearce, E.J.5    Sher, A.6
  • 46
    • 0027409771 scopus 로고
    • Interferon-γ inhibits interleukin 10 production by monocytes
    • Chomarat, P., M-C. Risson, J. Banchereau, and P. Miosse. 1993. Interferon-γ inhibits interleukin 10 production by monocytes. J. Exp. Med. 177:523.
    • (1993) J. Exp. Med. , vol.177 , pp. 523
    • Chomarat, P.1    Risson, M.-C.2    Banchereau, J.3    Miosse, P.4
  • 48
    • 0023197097 scopus 로고
    • Interferon γ and B cell stimulatory factor 1 reciprocally regulate Ig isotype production
    • Snapper, C. M., and W. E. Paul. 1987. Interferon γ and B cell stimulatory factor 1 reciprocally regulate Ig isotype production. Science 236:944.
    • (1987) Science , vol.236 , pp. 944
    • Snapper, C.M.1    Paul, W.E.2
  • 50
    • 0027422313 scopus 로고
    • + T cells from αβ TCR mice: IL-12 substitution for macrophages to stimulate IFNγ production is IFNγ-dependent
    • + T cells from αβ TCR mice: IL-12 substitution for macrophages to stimulate IFNγ production is IFNγ-dependent. Int. Immunol. 5:1119.
    • (1993) Int. Immunol. , vol.5 , pp. 1119
    • Macatonia, S.E.1    Hsieh, C.-S.2    Murphy, K.M.3    O'Garra, A.4
  • 51
    • 0027255488 scopus 로고
    • + T cell subsets and induces early resistance to Leishmania major in mice
    • + T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178:567.
    • (1993) J. Exp. Med. , vol.178 , pp. 567
    • Scharton, T.M.1    Scott, P.2
  • 52
    • 0028862097 scopus 로고
    • Nonviable bacterial antigens administered with IL-12 generate antigen-specific T cell responses and protective immunity against Listeria monocytogenes
    • Miller, M. A., M. J. Skeen, and H. K. Ziegler. 1995. Nonviable bacterial antigens administered with IL-12 generate antigen-specific T cell responses and protective immunity against Listeria monocytogenes. J. Immunol. 155:4817.
    • (1995) J. Immunol. , vol.155 , pp. 4817
    • Miller, M.A.1    Skeen, M.J.2    Ziegler, H.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.