A new real-time morphology classification for human spermatozoa: a link for fertilization and improved embryo quality

Fertility and Sterility

Volumn 92, Issue 5, 2009, Pages 1616-1625

  Cassuto, Nino Guy ^a   Bouret, Dominique ^a   Plouchart, Jean Michel ^a   Jellad, Sonia ^a   Vanderzwalmen, Pierre ^a   Balet, Richard ^b   Larue, Lionel ^c   Barak, Yona ^d  

^a Laboratory Drouot Unit AMP   (France)

^b Bleuets Hospital   (France)

^c Saint Simon Diaconnesses Hospital   (France)

^d Dr Yona Barak Laboratories Ltd   (Israel)

Author keywords

age related fertilization; embryo morphology; fertilization potential; ICSI; motile spermatozoon; real time sperm scoring scale; Sperm morphology

Indexed keywords

NAFARELIN ACETATE; ORGANON; OVITREL; RECOMBINANT CHORIONIC GONADOTROPIN; RECOMBINANT FOLLITROPIN; TRIPTORELIN; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; ARTICLE; CELL ASSAY; CELL SHAPE; CELL SIZE; CELL STRUCTURE; CELL VACUOLE; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; FERTILIZATION; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MALE; MALE INFERTILITY; MATERNAL AGE; OOCYTE; OUTCOME ASSESSMENT; OVARY HYPERSTIMULATION; PRIORITY JOURNAL; SCORING SYSTEM; SPERM RETRIEVAL; SPERMATOZOON; SPERMATOZOON MOTILITY;

ADULT; BLASTOCYST; CELL SHAPE; CELLS, CULTURED; COMPUTER SYSTEMS; EMBRYONIC DEVELOPMENT; FEMALE; FERTILIZATION; HUMANS; INFERTILITY, MALE; MALE; OVULATION INDUCTION; PREGNANCY; PREGNANCY RATE; QUALITY CONTROL; RETROSPECTIVE STUDIES; SEMEN ANALYSIS; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA;

EID: 70350565048     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.08.088     Document Type: Article

References (46)

1. Palermo G., Joris H., Devroy P., and Van Steirteghem A.C. Pregnancies after intracytoplasmic sperm injection of single spermatozoon into an oocyte. Lancet 340 (1992) 17-18
2. Ménézo Y., and Barak Y. Comparison between day-2 embryos obtained either from ICSI or resulting from short insemination IVF: Influence of maternal age. Hum Reprod 15 (2000) 1776-1780
3. Mansour R.T., Aboulghar M.A., Serour G.I., Amin Y.M., and Ramzi A.M. The effect of sperm parameters on the outcome of intracytoplasmic sperm injection. Fertil Steril 64 (1995) 982-986
4. Nagy Z.P., Liu J., Joris M., Verheyen G., Tournaye H., Camus M., et al. The result of intracytoplasmic sperm injection is not related to any of the three basic sperm parameters. Hum Reprod 10 (1995) 1123-1129
5. Svalender P., Forsberg A.S., Jakobsson A.H., and Wikland M. Factors of importance for the establishment of a successful program of intracytoplasmic sperm injection treatment for male infertility. Fertil Steril 63 (1995) 828-837
6. Nagy Z.P., Verheyen G., Tournaye H., and Van Steirteghem A.C. Special applications of intracytoplasmic sperm injection: the influence of sperm count, motility, morphology, source and sperm antibody on the outcome of ICSI. Hum Reprod 13 Suppl 1 (1998) 143-154
7. Oehninger S., Chaturvedi S., Toner J., Morshedi M., Mayer J., Lanzendorf S., et al. Semen quality: is there a paternal effect on pregnancy outcome in in-vitro fertilization/intracytoplasmic sperm injection?. Hum Reprod 13 (1998) 2161-2164
8. Sukcharoen N., Sithipravej T., Promviengchai S., Chinpilas V., and Boonkasemsanti W. Sperm morphology evaluated by computer (IVOS) cannot predict the fertilization rate in vitro after intracytoplasmic sperm injection. Fertil Steril 69 (1998) 564-568
9. Kupker W., Schulze W., and Diedrich K. Ultrastructure of gametes and intracytoplasmic sperm injection: the significance of sperm morphology. Hum Reprod 13 Suppl 1 (1998) 99-106
10. Ludwig M., and Katalinic A. Pregnancy course and health of children born after ICSI depending on parameters of male factor infertility. Hum Reprod 18 (2003) 351-357
11. Gardner D.K., Schoolcraft W.B., Wagley L., Schlenker T., Stevens J., and Hesla J. A prospective randomized trial of blastocyst culture and transfer in in vitro fertilization. Hum Reprod 13 (1998) 3434-3440
12. Kruger T.F., Menkveld R., Stander F.S., Lombard C.J., Van der Merwe J.P., van Zyl J.A., et al. Sperm morphologic features as a prognostic factor in in vitro fertilization. Fertil Steril 46 (1986) 1118-1123
13. Ménézo Y., and Dale B. Paternal contribution to successful embryogenesis. Hum Reprod 10 (1994) 1326-1328
14. Jones G.M., Trouson A.O., Lolatgis N., and Wood C. Factors affecting the success of human blastocyst development and pregnancy following in vitro fertilization and embryo transfer. Fertil Steril 70 (1998) 1022-1029
15. Shoukir Y., Chardonnens D., Campana A., and Sakkas D. Blastocyst development from supernumerary embryos after intracytoplasmic sperm injection: a paternal influence?. Hum Reprod 13 (1998) 1632-1637
16. Miller J.E., and Smith T. The effect of intracytoplasmic sperm injection and semen parameters on blastocyst development in vitro. Hum Reprod 16 (2001) 918-924
17. Cassuto G., Chavrier M., and Menezo Y. Culture conditions and not prolonged culture time are responsible for monozygotic twinning in human in vitro fertilization. Fertil Steril 80 (2003) 462-463
18. Loutradi K.E., Tarlatzis B.C., Goulis D.G., Zepiridis L., Pagou T., Chatziioannou E., et al. The effects of sperm quality on embryo development after intracytoplasmic sperm injection. J Assist Reprod Genet 23 (2006) 69-74
19. Hewitson L., Simerly C., and Schatten G. Inheritance defects of the sperm centrosome in humans and its possible role in male infertility. Int J Androl 3 Suppl 20 (1997) 35-43
20. Hewitson L., Dominko T., Takahashi D., Martinovich C., Ramalho-Santos J., Sutovsky P., et al. Unique checkpoints during the first cell cycle of fertilisation after intracytoplasmic sperm injection in Rhesus monkeys. Nature Med 5 (1999) 431-433
21. De Vos A., Van De Velde H., Joris H., Verheyen G., Devroey P., and Van Steirteghem A. Influence of individual sperm morphology on fertilization, embryo morphology, and pregnancy outcome of intracytoplasmic sperm injection. Fertil Steril 79 (2003) 42-48
22. Bartoov B., Berkovitz A., Eltes F., Kogosowski A., Menezo Y., and Barak Y. Breakthroughs in andrology: real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome. J Androl 23 (2002) 1-8
23. Bartoov B., Berkovitz A., Eltes F., Kogosovsky A., Yagoda A., Lederman H., et al. Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection. Fertil Steril 80 (2003) 1413-1419
24. Junca A.M., Cohen-Bacrie P., and Hazout A. Improvement of fertilization and pregnancy rate after intracytoplasmic fine morphology selected sperm injection [abstract]. Fertil Steril 82 Suppl 2 (2004) S173
25. Hazout A., Dumont-Hassan M., Junca A.M., Cohen Bacrie P., and Tesarik J. High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Reprod Biomed Online 12 (2006) 19-25
26. Berkovitz A., Eltes F., Yaari S., Katz N., Barr I., Fishman A., et al. The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Hum Reprod 20 (2005) 185-190
27. Auger J., and Eustache F. Standardisation de la classification morphologique des spermatozoïdes humains selon la méthode de David modifiée. Andrologie 10 (2000) 358-373
28. World Health Organization. Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. (1999), Cambridge University Press, Cambridge
29. Vanderzwalmen P., Bertin G., Lejeune B., Nijs M., Vandamme B., and Schoysman R. Two essential steps for a successful intracytoplasmic sperm injection: injection of immobilized spermatozoa after rupture of the oolema. Hum Reprod 11 (1996) 540-547
30. El-Ghobashy A.A., and West C.R. The human sperm head: a key for successful fertilization. J Androl 24 (2003) 232-238
31. Gardner D.K., Lane M., Stevens J., Schlenker T., and Schoolcraft W.B. Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil Steril 73 (2000) 1155-1158
32. Aitken R.J. Origins and consequences of DNA damage in male germ cells. Reprod Biomed Online 14 (2007) 727-733
33. Cassuto G.N., Vanderzwalmen P., Plouchart J.M., Balet R., Larue L., and Bouret D. How to improve the rate of good quality blastocysts after ICSI in a new approach for classification of motile human spermatozoa [abstract]. Fertil Steril 88 Suppl 1 (2007) S90
34. Barak Y., and Goldman S. Development of in vitro human embryo. In: Allahbadia G., and Merchant R. (Eds). Contemporary perspectives on assisted reproductive technology (2006), Reed Elsevier, New Delhi 80-88
35. Rawe V.Y., Terada Y., Nakamura S., Chillik C.F., Olmedo S.B., and Chemes H.E. A pathology of the sperm centriole responsible for defective sperm aster formation, syngamy and cleavage. Hum Reprod 17 (2002) 2344-2349
36. Tesarik J. Paternal effects on cell division in the preimplantation embryo. Reprod Biomed Online 10 (2005) 370-375
37. Palermo G.D., Colombero L.T., and Rosenwaks Z. The human sperm centrosome is responsible for normal syngamy and early embryonic development. Revue Reprod 2 (1997) 19-27
38. Sathananthan A.H. Paternal centrosomal dynamics in early human development and infertility. J Assist Reprod Genet 15 (1998) 129-139
39. Rawe V.Y., Galaverna G.D., Nodar F.N., Brugo-Olmedo S., and Vitullo A.D. Cellular events during fertilization failure in humans. Fertil Steril 76 (2001) 375-376
40. Dittrich R., Maltaris T., Dragonas C., Huber C., Beckmann M.W., and Kiesewetter F. Individual assessment of sperm morphology of single spermatozoa used for intracytoplasmic sperm injection. Andrologia 37 (2005) 53-56
41. Sakkas D., Urner F., Bizzaro D., Manicardi G., Bianchi P.G., Shoukir Y., et al. Sperm nuclear DNA damage and altered chromatin structure: effect on fertilization and embryo development. Hum Reprod 13 Suppl 4 (1998) 11-19
42. Lopes S., Jurisicova A., and Casper R.F. Gamete-specific DNA fragmentation in unfertilized human oocytes after intracytoplasmic sperm injection. Hum Reprod 13 (1998) 703-708
43. Mundy A.J., Ryder T.A., and Edmonds D.K. A quantitative study of sperm head ultrastructure in subfertile males with excess sperm precursors. Fertil Steril 61 (1994) 751-754
44. Piette C., de Mouzon J., Bachelot A., and Spira A. In-vitro fertilization: influence of women's age on pregnancy rates. Hum Reprod 5 (1990) 56-59
45. Janny L., and Menezo Y.J. Maternal age effect on early human embryonic development and blastocyst formation. Mol Reprod Dev 45 (1996) 31-37
46. Menezo Y. Paternal and maternal factors in pre-implantation embryogenesis: interaction with the biochemical environment. Reprod Biomed Online 12 (2006) 616-621