Relative abundance of selenoprotein P isoforms in human plasma depends on genotype, se intake, and cancer status

Antioxidants and Redox Signaling

Volumn 11, Issue 11, 2009, Pages 2631-2640

  Méplan, Catherine ^a   Nicol, Fergus ^b   Burtle, Brian T ^a   Crosley, Lynne K ^b   Arthur, John R ^b   Mathers, John C ^a   Hesketh, John E ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MESSENGER RNA; PROTEIN SEPP 1; SELENOPROTEIN P; SODIUM SELENITE; UNCLASSIFIED DRUG; ISOPROTEIN; SELENIUM;

ADULT; ARTICLE; CANCER RISK; CLINICAL ARTICLE; COLON CANCER; COLORECTAL CANCER; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MALE; NEOPLASM; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; VITAMIN SUPPLEMENTATION; WESTERN BLOTTING; BLOOD; COLORECTAL TUMOR; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; POLYACRYLAMIDE GEL ELECTROPHORESIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; BLOTTING, WESTERN; COLORECTAL NEOPLASMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; SELENIUM; SELENOPROTEIN P; YOUNG ADULT;

EID: 70350538416     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2009.2533     Document Type: Article

References (34)

1. Akesson B, Bellew T, and Burk RF. Purification of selenoprotein P from human plasma. Biochim Biophys Acta 1204: 243-249, 1994.
2. Al-Taie OH, Uceyler N, Eubner U, Jakob F, Mork H, Scheurlen M, Brigelius-Flohe R, Schottker K, Abel J, Thalheimer A, Katzenberger T, Illert B, Melcher R, and Kohrle J. Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis. Nutr Cancer 48: 6-14, 2004.
3. Banning A, Kipp A, Schmitmeier S, Lowinger M, Florian S, Krehl S, Thalmann S, Thierbach R, Steinberg P, and Brigelius-Flohe R. Glutathione peroxidase 2 inhibits cyclooxygenase-2-mediated migration and invasion of HT-29 adenocarcinoma cells but supports their growth as tumors in nude mice. Cancer Res 68: 9746-9753, 2008.
4. Beck MA, Levander OA, and Handy J. Selenium deficiency and viral infection. J Nutr 133: 1463S-1467S, 2003.
5. Bermano G, Pagmantidis V, Holloway N, Kadri S, Mowat NA, Shiel RS, Arthur JR, Mathers JC, Daly AK, Broom J, and Hesketh JE. Evidence that a polymorphism within the 3′UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer. Genes Nutr 2: 225-232, 2007.
6. Brigelius-Flohe R. Glutathione peroxidases and redoxregulated transcription factors. Biol Chem 387: 1329-1335, 2006.
7. Burk RF and Hill KE. Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Annu Rev Nutr 25: 215-315, 2005.
8. Clark LC, Combs GF Jr, Turnbull BW, Slate EH, Chalker DK, Chow J, Davis LS, Glover RA, Graham GF, Gross EG, Krongrad A, Lesher JL Jr, Park HK, Sanders BB Jr, Smith CL, and Taylor JR. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial: Nutritional Prevention of Cancer Study Group. JAMA 276: 1957-1963, 1996.
9. Combs GF Jr. Current evidence and research needs to support a health claim for selenium and cancer prevention. J Nutr 135: 343-347, 2005.
10. Duffield AJ, Thomson CD, Hill KE, and Williams S. An estimation of selenium requirements for New Zealanders. Am J Clin Nutr 70: 896-903, 1999.
11. Hill KE, Lloyd RS, and Burk RF. Conserved nucleotide sequences in the open reading frame and 3′ untranslated region of selenoprotein P mRNA. Proc Natl Acad Sci U S A 90: 537-541, 1993.
12. Hill KE, Zhou J, McMahan WJ, Motley AK, Atkins JF, Gesteland RF, and Burk RF. Deletion of selenoprotein P alters distribution of selenium in the mouse. J Biol Chem 278: 13640-13646, 2003.
13. Jacobs ET, Jiang R, Alberts DS, Greenberg ER, Gunter EW, Karagas MR, Lanza E, Ratnasinghe L, Reid ME, Schatzkin A, Smith-Warner SA, Wallace K, and Martinez ME. Selenium and colorectal adenoma: results of a pooled analysis. J Natl Cancer Inst 96: 1669-1675, 2004.
14. Kabuyama Y, Oshima K, Kitamura T, Homma M, Yamaki J, Munakata M, and Homma Y. Involvement of selenoprotein P in the regulation of redox balance and myofibroblast viability in idiopathic pulmonary fibrosis. Genes Cells 12: 1235-1244, 2007.
15. Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, Parnes HL, Minasian LM, Gaziano JM, Hartline JA, Parsons JK, Bearden JD 3rd, Crawford ED, Goodman GE, Claudio J, Winquist E, Cook ED, Karp DD, Walther P, Lieber MM, Kristal AR, Darke AK, Arnold KB, Ganz PA, Santella RM, Albanes D, Taylor PR, Probstfield JL, Jagpal TJ, Crowley JJ, Meyskens FL Jr, Baker LH, and Coltman CA Jr. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 301: 39-51, 2009.
16. Lu J and Holmgren A. Selenoproteins. J Biol Chem 284: 723-727, 2009.
17. Ma S, Hill KE, Caprioli RM, and Burk RF. Mass spectrometric characterization of full-length rat selenoprotein P and three isoforms shortened at the C terminus: evidence that three UGA codons in the mRNA open reading frame have alternative functions of specifying selenocysteine insertion or translation termination. J Biol Chem 277: 12749-12754, 2002.
18. Meplan C, Crosley LK, Nicol F, Beckett GJ, Howie AF, Hill KE, Horgan G, Mathers JC, Arthur JR, and Hesketh JE. Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study). FASEB J 21: 3063-3074, 2007. (Pubitemid 47565527)
19. Mostert V, Lombeck I, and Abel J. A novel method for the purification of selenoprotein P from human plasma. Arch Biochem Biophys 357: 326-330, 1998.
20. Murawaki Y, Tsuchiya H, Kanbe T, Harada K, Yashima K, Nozaka K, Tanida O, Kohno M, Mukoyama T, Nishimuki E, Kojo H, Matsura T, Takahashi K, Osaki M, Ito H, Yodoi J, Murawaki Y, and Shiota G. Aberrant expression of selenoproteins in the progression of colorectal cancer. Cancer Lett 259: 218-230, 2008.
21. Peters U, Chatterjee N, Hayes RB, Schoen RE, Wang Y, Chanock SJ, and Foster CB. Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol Biomarkers Prev 17: 1144-1154, 2008.
22. Powers HJ, Hill MH, Welfare M, Spiers A, Bal W, Russell J, Duckworth Y, Gibney E, Williams EA, and Mathers JC. Responses of biomarkers of folate and riboflavin status to folate and riboflavin supplementation in healthy and colorectal polyp patients (the FAB2 Study). Cancer Epidemiol Biomarkers Prev 16: 2128-2135, 2007.
23. Rayman MP. The importance of selenium to human health. Lancet 356: 233-241, 2000.
24. Rayman MP. Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc Nutr Soc 64: 527-542, 2005.
25. Riese C, Michaelis M, Mentrup B, Gotz F, Kohrle J, Schweizer U, and Schomburg L. Selenium-dependent preand posttranscriptional mechanisms are responsible for sexual dimorphic expression of selenoproteins in murine tissues. Endocrinology 147: 5883-5892, 2006.
26. Russo MW, Murray SC, Wurzelmann JI, Woosley JT, and Sandler RS. Plasma selenium levels and the risk of colorectal adenomas. Nutr Cancer 28: 125-129, 1997.
27. Saito Y, Sato N, Hirashima M, Takebe G, Nagasawa S, and Takahashi K. Domain structure of bi-functional selenoprotein P. Biochem J 381: 841-846, 2004.
28. Schomburg L. Selene, the goddess of the moon: does she shine on men only? Eur Heart J 28: 2043-2044, 2007.
29. Schomburg L, Schweizer U, Holtmann B, Flohe L, Sendtner M, and Kohrle J. Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J 370: 397-402, 2003.
30. Steinbrenner H, Alili L, Bilgic E, Sies H, and Brenneisen P. Involvement of selenoprotein P in protection of human astrocytes fromoxidative damage. Free RadicBiolMed 40: 1513-1523, 2006.
31. Steinbrenner H, Alili L, Stuhlmann D, Sies H, and Brenneisen P. Post-translational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells. Biol Chem 388: 1043-1051, 2007.
32. Thomson CD, Robinson MF, Butler JA, and Whanger PD. Long-term supplementation with selenate and selenomethionine: selenium and glutathione peroxidase (EC 1.11.1.9) in blood components of New Zealand women. Br J Nutr 69: 577-588, 1993.
33. Whanger PD. Selenium and its relationship to cancer: an update digger. Br J Nutr 91: 11-28, 2004.
34. Xia Y, Hill KE, Byrne DW, Xu J, and Burk RF. Effectiveness of selenium supplements in a low-selenium area of China. Am J Clin Nutr 81: 829-834, 2005.