Successful clinical islet isolation using a GMP-manufactured collagenase and neutral protease

Transplantation

Volumn 88, Issue 6, 2009, Pages 753-756

  Szot, Gregory L ^a   Lee, Michael R ^a   Tavakol, Mohammad M ^b   Lang, Jiena ^a   Dekovic, Florinna ^a   Kerlan, Robert K ^b   Stock, Peter G ^b   Posselt, Andrew M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Collagenase; Islet isolation; Islet transplantation; Pancreas procurement.

Indexed keywords

COLLAGENASE; NEUTRAL PROTEINASE; THERMOLYSIN;

ACINAR CELL; ALLOTRANSPLANTATION; BODY MASS; BOVINE SPONGIFORM ENCEPHALOPATHY; CELL CULTURE; CONTAMINATION; DISEASE TRANSMISSION; DONOR SELECTION; ECHOGRAPHY; ENZYME DEGRADATION; ENZYME ENGINEERING; FEMALE; FOLLOW UP; HUMAN; ISOLATION PROCEDURE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROCESSING; PURIFICATION; RISK FACTOR; SHORT SURVEY;

ADULT; ANIMALS; CATTLE; COLLAGENASES; HUMANS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MIDDLE AGED; PEPTIDE HYDROLASES; TISSUE AND ORGAN HARVESTING; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS;

EID: 70350523680     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181b443ae     Document Type: Short Survey

References (21)

1. Fiorina P, Shapiro AMJ, Ricordi C, et al. The clinical impact of islet transplantation. Am J Transplant 2008; 8: 1990.
2. Fetterhoff TJ, Cavanagh TJ, Wile KJ, et al. Human pancreatic dissociation using a purified enzyme blend. Transplant Proc 1995; 27: 3282.
3. Wile KJ, Fetterhoff TJ, Cavanagh TJ, et al. Image analysis of human pancreatic islets: A time-course approach to the evaluation of pancreatic dissociation. Transplant Proc 1995; 27: 3246.
4. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free im-munosuppressive regimen. N Engl J Med 2000; 343: 230.
5. Toso C, Oberholzer J, Ris F, et al. Factors affecting human islet of Langerhans isolation yields. Transplant Proc 2002; 34: 3.
6. Linetsky E, Bottino R, Lehman R, et al. Improved human islet isolation using a new enzyme blend, Liberase. Diabetes 1997; 46: 1120
7. Cell therapy society web site 2007. Available at: http://www. celltherapysociety.org/files/PDF/Resources/Risk-BSE-in-Collagenase- Enzymes.pdf. Accessed March 1, 2009.
8. Food and Drug Administration Web Site: Use of Materials Derived from Cattle in Medical Products Intended for Use in Humans and Drugs Intended for Use in Ruminants, 2007. Available at: http://www. fda.gov/cber/rules/catruminant. htm. Accessed March 1, 2009.
9. Clinical islet transplantation consortium web site. Available at: www.citisletstudy.org. Accessed March 1, 2009.
10. Bucher P, Mathe Z, Bosco D, et al. Serva collagenase NB1: A new enzyme preparation for human islet isolation. Transplant Proc 2004; 36: 1143.
11. Brandhorst H, Friberg A, Andersson HH, et al. The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation. Transplantation 2009; 87: 370.
12. S. Matsumoto, G. Zhanga, S. Qualleya, et al. The effect of two-layer (University of Wisconsin solution/perfluorochemical) preservation method on clinical grade pancreata prior to islet isolation and transplantation. Transplant Proc 2004; 36: 1037.
13. Hering BJ, Kandaswamy R, Harmon JV, et al. Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody. Am J Transplant 2004; 4: 390.
14. Bucher P, Mathe Z, Morel P, et al. Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation. Transplantation 2005; 79: 91. SERVA Electrophoresis Web site: Available at: www.serva.de/enDE/ index.html. Accessed March 1, 2009.
15. Oberholzer J, Triponez F, Mage R, et al. Human islet transplantation: Lessons from 13 autologous and 13 allogeneic transplantations. Transplantation 2000; 69: 1115.
16. Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes 1988; 37: 413.
17. Matsumoto S, Zhang HJ, Gilmore T, et al. Large scale isopycnic islet purification utilizing non-toxic, endotoxin free media facilitates immediate single-donor pig islet allograft function [abstract]. Transplantation 1998; 66(suppl): 530.
18. van der Burgh MPM, Ranuncoli A, Molano R, et al. New powerful tool for human islet purification optiprep-UWS [abstract]. Presented atthe Seventh World Congress Pancreas and Islet Transplant Association, Sydney, Australia, 1999.
19. Lake SP, Bassett PD, Larkins A, et al. Large-scale purification of human islets utilizing discontinuous albumin gradient on IBM2991 cell separator. Diabetes 1989; 38(suppl 1): 143.
20. Jahr H, Hussmann B, Eckhard T, et al. Successful single donor islet allotransplantation in the streptozotocin diabetes rat model. Cell Transplant 2002; 11: 513.
21. Owen RJ, Ryan EA, O'Kelly K, et al. Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: Radiologic aspects. Radiology 2003; 229: 165.