Binomial mixture model-based association tests under genetic heterogeneity

Annals of Human Genetics

Volumn 73, Issue 6, 2009, Pages 614-630

  Zhou, Hui ^a   Pan, Wei ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Case control study; EM algorithm; Genome wide association study; Likelihood ratio test; Linkage disequilibrium (LD); Mixture models; Permutation

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINOMIAL DISTRIBUTION; BIOINFORMATICS; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MATHEMATICAL MODEL; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ALGORITHMS; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; GENETIC ASSOCIATION STUDIES; GENETIC HETEROGENEITY; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 70350521744     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/j.1469-1809.2009.00542.x     Document Type: Article

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