Impact of radiotherapy on fertility in female patients;Impact de la radiothérapie sur la fertilité féminine

Bulletin du Cancer

Volumn 96, Issue 10, 2009, Pages 1005-1011

  Chargari, C ^a   Castadot, P ^b   Gillion, N ^c   Bauduceau, O ^a   Vedrine L ^a   Haie Meder, C ^d   Spano, J P ^c   Magne N ^c  

^a University of Paris Descartes   (France)

^b JULES BORDET INSTITUTE   (Belgium)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Fertility; Late toxicity; Low dose irradiation; Ovarian transposition; Radiation oncology

Indexed keywords

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; FEMALE FERTILITY; FEMALE INFERTILITY; GENITAL SYSTEM; HUMAN; LOW ENERGY RADIATION; OVARY FUNCTION; REPRODUCTION; REVIEW; AGE; FEMALE; FERTILITY; JAPAN; OVARY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIOACTIVE WASTE;

AGE FACTORS; FEMALE; FERTILITY; HUMANS; INFERTILITY, FEMALE; JAPAN; OVARY; RADIATION INJURIES; RADIOACTIVE FALLOUT; RADIOTHERAPY DOSAGE;

EID: 70350518865     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1684/bdc.2009.0949     Document Type: Review

References (44)

1. Charvolin JY, Nos C, de la Rochefordière A, Margerie VJ, Durand JC, Clough KB. Relevance of combined radiation and surgical treatment of early invasive carcinoma of the cervix. Bull Cancer 2001 ; 88 : 1207-1212
2. Lerouge D, Touboul E, Lefranc JP, Uzan S, Jannet D, Moureau-Zabotto L, et al. Preoperative concurrent radiation therapy and chemotherapy for operable bulky carcinomas of uterine cervix stages IB2, IIA and IIB with proximal parametrial invasion. Cancer Radiother 2004 ; 8 : 168-177
3. Haie-Meder C, de Crevoisier R, Bruna A, Lhommé C, Pautier P, Morice P, et al. Concomitant chemoradiation in patients with cervix cancer. Bull Cancer 2005 ; 92 : 1032-1038 (Pubitemid 43081255)
4. Querleu D, Gladieff L, Delannes M, Mery E, Ferron G, Rafii A. Preservation of fertility in gynaecologic cancers. Bull Cancer 2008 ; 95 : 487-494
5. Lushbaugh CC, Casarett GW. The effects of gonadal irradiation in clinical radiation therapy. A review. Cancer 1976 ; 37 : 1111-1120
6. Klapouszczak D, Bertozzi-Salamon AI, Grandjean H, Arnaud C. Fertility preservation in adolescent cancer patients. Bull Cancer 2007 ; 94 : 636-646 (Pubitemid 47413885)
7. Grigsby PW, Russell A, Bruner D, Eifel P, Koh WJ, Spanos W, et al. Late injury of cancer therapy on the female reproductive tract. Int J Radiat Oncol Biol Phys 1995 ; 31 : 1281-1299
8. Hawkins MM, Smith RA. Pregnancy outcomes in childhood cancer survivors: probable effects of abdominal irradiation. Int J Cancer 1989 ; 43 : 399-402.
9. Flamant F, Gerbaulet A, Nihoul-Fekete C, Valteau-Couanet D, Chassagne D, Lemerle J. Long-term sequelae of conservative treatment by surgery, brachytherapy and chemotherapy for vulval and vaginal rhabdomyosarcoma in children. J Clin Oncol 1990 ; 8 : 1847-1853 (Pubitemid 20382347)
10. Sanders JE, Hawley J, Levy W, Gooley T, Buckner CD, Deeg HJ, et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood 1996 ; 87 : 3045-3052 (Pubitemid 26102258)
11. Magné N, Haie-Meder C. Brachytherapy for genital-tract rhabdomyosarcomas in girls: technical aspects, reports and perspectives. Lancet Oncol 2007 ; 8 : 725-729 (Pubitemid 47163588)
12. Magné N, Oberlin O, Martelli H, Gerbaulet A, Chassagne D, Haie-Meder C. Vulval and vaginal rhabdomyosarcoma in children: update and reappraisal of Institut Gustave-Roussy brachytherapy experience. Int J Radiat Oncol Biol Phys 2008 ; 72 : 878-883
13. Byrne J, Mulvihill JJ, Myers MH, Connelly RR, Naughton MD, Kraus MR, et al. Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer. N Engl J Med 1987 ; 317 : 1315-1321 (Pubitemid 17153013)
14. Green DM, Kawashima T, Stovall M, Leisenring W, Sklar CA, Mertens AC, et al. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. J Clin Oncol 2009 ; 27 : 2677-2685 (Pubitemid 44018918)
15. Perez CA, Grigsby PW, Garipagaoglu M, Mutch DG, Lockett MA. Factors affecting long-term outcome of irradiation in carcinoma of the vagina. Int J Radiat Oncol Biol Phys 1999 ; 44 : 37-45. (Pubitemid 29186186)
16. Tan LT, Zahra M. Long-term survival and late toxicity after chemoradiotherapy for cervical cancer - the Addenbrooke's experience. Clin Oncol (R Coll Radiol) 2008 ; 20 : 358-364
17. Barillot I, Maingon P, Truc G, Horiot JC. Complications of treatments of invasive cancers of the uterine cervix with intact uterus: results and prevention. Cancer Radiother 2000 ; 4 : 147-158 (Pubitemid 30238927)
18. Perez CA, Fox S, Lockett MA, Grigsby PW, Camel HM, Galakatos A, et al. Impact of dose in outcome of irradiation alone in carcinoma of the uterine cervix: analysis of two different methods. Int J Radiat Oncol Biol Phys 1991 ; 21 : 885-898
19. Critchley HO, Wallace WH, Shalet SM, Mamtora H, Higginson J, Anderson DC. Abdominal irradiation in childhood; the potential for pregnancy. Br J Obstet Gynaecol 1992 ; 99 : 392-394
20. Critchley HO. Factors of importance for implantation and problems after treatment for childhood cancer. Med Pediatr Oncol 1999 ; 33 : 9-14.
21. Fehr PE, Prem KA. Malignancy of the uterine corpus following irradiation therapy for squamous cell carcinoma of the cervix. Am J Obstet Gynecol 1974 ; 119 : 685-692
22. Aartsen EJ. Fluid detection in the uterus during and after irradiation for carcinoma of the cervix - clinical implications. Eur J Surg Oncol 1990 ; 16 : 42-46 (Pubitemid 20079462)
23. Bruner DW, Lanciano R, Keegan M, Corn B, Martin E, Hanks GE. Vaginal stenosis and sexual function following intracavitary radiation for the treatment of cervical and endometrial carcinoma. Int J Radiat Oncol Biol Phys 1993 ; 27 : 825-830 (Pubitemid 23340292)
24. Rubin P, Casarett GW. Clinical radiation pathology as applied to curative radiotherapy. Cancer 1968 ; 22 : 767-778
25. Clavère P, Berdah JF, Tubiana N. Méthodes non chirurgicales de protection de la fertilité lors des traitements anticancéreux. In: Fertilité après traitements anticancéreux. Aubard Y, Olivennes F, editors. Paris: Masson, 1999.
26. Haie-Meder C, Mlika-Cabanne N, Michel G, Briot E, Gerbaulet A, Lhomme C, et al. Radiotherapy after ovarian transposition: ovarian function and fertility preservation. Int J Radiat Oncol Biol Phys 1993 ; 25 : 419-424 (Pubitemid 23068707)
27. Thibaud E, Ramirez M, Brauner R, Flamant F, Zucker JM, Fékété C, et al. Preservation of ovarian function by ovarian transposition performed before pelvic irradiation during childhood. J Pediatr 1992 ; 121 : 880-884
28. Kalapurakal JA, Peterson S, Peabody EM, Thomas PR, Green DM, D'Angio GJ, et al. Pregnancy outcomes after abdominal irradiation that included or excluded the pelvis in childhood Wilms tumor survivors: a report from the National Wilms Tumor Study. Int J Radiat Oncol Biol Phys 2004; 58:1364-1368. (Pubitemid 38438295)
29. Stockle E, Verdier G, Thomas L, Bussières E, Avril A, Lakdja F, et al. Functional outcome of laparoscopically transposed ovaries in the multidisciplinary treatment of cervical cancers. Analysis of risk factors. J Gynecol Obstet Biol Reprod (Paris) 1996 ; 25 : 244-252 (Pubitemid 126753859)
30. Morice P, Wicart-Poque F, Rey A, Camatte S, Rouzier R, Pautier P, et al. Results and fertility after conservative treatment of invasive epithelial ovarian cancer. Gynecol Obstet Fertil 2002 ; 30 : 684-691
31. Hodel K, Rich WM, Austin P. The role of ovarian transposition in conservation of ovarian function in radical hysterectomy followed by pelvic radiation. Gynecol Oncol 1982 ; 13 : 195-202.
32. Morice P, Pautier P, Fanchin R, Haie-Meder C, Chauveaud- Lambling A, Frydman R, et al. Therapy insight: fertility in women after cancer treatment. Nat Clin Pract Endocrinol Metab 2007 ; 3 : 819-826 (Pubitemid 350145524)
33. Porcu G. Transposition de l'ovaire. In: Fertilité après traitements anticancéreux. Aubard Y, Olivennes F, editors. Paris: Masson, 1999.
34. Tao T, Del Valle A. Human oocyte and ovarian tissue cryopreservation and its application. J Assist Reprod Genet 2008 ; 25 : 287-296
35. Deepinder F, Agarwal A. Technical and ethical challenges of fertility preservation in young cancer patients. Reprod Biomed Online 2008 ; 16 : 784-791 (Pubitemid 351865340)
36. Oughterson A, Warren S. Medical effects of the atomic bomb in Japan. New York : McGraw Hill, 1956.
37. Yamazaki JN, Wright SW, Wright PM. Outcome of pregnancy in women exposed to the atomic bomb in Nagasaki. Amer J Dis Child 1954 ; 87 : 448-463
38. Seigel D. Frequency of live births among survivirs of the atomic bombs Hiroshima and Nagasaki. Atomic Bomb Casualty Commission TR 1-68, 1968.
39. Neel JV, Schull WJ. The effect of exposure to the atomic bomb on pregnancy termination in Hiroshima and Nagasaki. National Academy of Sciences-National Research Council, Publication no 461, 1956.
40. Blot WJ, Sawada H. Fertility among female survivors of the atomic bombs of Hiroshima and Nagasaki. Amer J Hum Genet 1972 ; 24 : 613-622
41. Milton RC, Shohoji T. Tentative 1965 radiation dose estimation for atomic bomb survivors, Hiroshima and Nagasaki. Atomic Bomb Casualty Commission TR 1-68, 1968.
42. Shamsaldin A, Grimaud E, Hardiman C, Diallo I, de-Vathaire F, Chavaudra J. Dose distribution throughout the body from radiotherapy for Hodgkin's disease in childhood. Radiother Oncol 1998 ; 49 : 85-90.
43. Niroomand-Rad A, Cumberlin R. Measured dose to ovaries and testes from Hodgkin's fields and determination of genetically significant dose. Int J Radiat Oncol Biol Phys 1993 ; 25 : 745-751 (Pubitemid 23099270)
44. Mazonakis M, Zacharopoulou F, Kachris S, Varveris C, Damilakis J, Gourtsoyiannis N. Scattered dose to gonads and associated risks from radiotherapy for common pediatric malignancies: a phantom study. Strahlenther Onkol 2007 ; 183 : 332-337 (Pubitemid 46996067)