Changes between 1982 and 2000 in the prevalence of behavioral symptoms and psychotropic drug treatment among old people with cognitive impairment in geriatric care

International Psychogeriatrics

Volumn 21, Issue 5, 2009, Pages 941-948

  Lövheim, Hugo ^a   Sandman, Per Olof ^b   Karlsson, Stig ^b   Gustafson, Yngve ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

Aggression; Alzheimer's disease; Antipsychotics; BPSD; Dementia; Nursing home; SSRI

Indexed keywords

ANTIDEPRESSANT AGENT; ANTIHISTAMINIC AGENT; ANXIOLYTIC AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BARBITAL; BENZODIAZEPINE DERIVATIVE; CHLORAL HYDRATE; CHOLINESTERASE INHIBITOR; HYPNOTIC SEDATIVE AGENT; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; NOOTROPIC AGENT; PROPIOMAZINE; PSYCHOTROPIC AGENT; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TETRACYCLIC ANTIDEPRESSANT AGENT; TRICYCLIC ANTIDEPRESSANT AGENT; ZIMELDINE; ZOPICLONE;

AGED; ARTICLE; BEHAVIOR DISORDER; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMOGRAPHY; DRUG USE; FEMALE; GERIATRIC CARE; HUMAN; INSTITUTIONAL CARE; LOCOMOTION; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; RATING SCALE; SWEDEN; TREATMENT REFUSAL; AGGRESSION; ALZHEIMER DISEASE; DRUG EFFECT; DRUG UTILIZATION; HEALTH SURVEY; HOME FOR THE AGED; MENTAL DISEASE; NURSING HOME; RESIDENTIAL HOME; STATISTICS; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; AGGRESSION; ALZHEIMER DISEASE; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; CROSS-SECTIONAL STUDIES; DRUG UTILIZATION; FEMALE; HEALTH SURVEYS; HOMES FOR THE AGED; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MENTAL DISORDERS; NURSING HOMES; PSYCHOTROPIC DRUGS; RESIDENTIAL FACILITIES; SWEDEN; TREATMENT OUTCOME;

EID: 70350517142     PISSN: 10416102     EISSN: 1741203X     Source Type: Journal    
DOI: 10.1017/S1041610209990329     Document Type: Article

References (30)

1. Adolfsson, R., Gottfries, C. G., Nyström, L. and Winblad, B. (1981). Prevalence of dementia disorders in institutionalized Swedish old people: the work load imposed by caring for these patients. Acta Psychiatrica Scandinavica, 63, 225-244
2. Ballard, C. et al. (2009). The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial. Lancet Neurology, 8, 151-157. doi: 10.1016/S1474-4422(08)70295-3
3. Black, W. and Almeida, O. P. (2004). A systematic review of the association between the Behavioral and Psychological Symptoms of Dementia and burden of care. International Psychogeriatrics, 16, 295-315. doi: 10.1017/ S1041610204000468 (Pubitemid 39441494)
4. Burns, A. and Rabins, P. (2000). Carer burden in dementia. International Journal of Geriatric Psychiatry, 15, S9-S13
5. Burns, A., O'Brien, J. and Ames, D. (2005). Dementia. 3rd edn. London: Hodder Arnold
6. Coehlo, D. P., Hooker, K. and Bowman, S. (2007). Institutional placement of persons with dementia: what predicts occurrence and timing? Journal of Family Nursing, 13, 253-277. doi: 10.1177/1074840707300947
7. Douglas, I. J. and Smeeth, L. (2008). Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ, 337, a1227. doi: 10.1136/bmj.a1227
8. Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198
9. Kallin, K., Gustafson, Y., Sandman, P. O. and Karlsson, S. (2004). Drugs and falls in older people in geriatric care settings. Aging Clinical and Experimental Research, 16, 270-276
10. Lebowitz, B. D. et al. (1997). Diagnosis and treatment of depression in late life: consensus statement update. JAMA, 278, 1186-1190
11. Lopez, O. L. et al. (2003). Patterns of change in the treatment of psychiatric symptoms in patients with probable Alzheimer's disease from 1983 to 2000. Journal of Neuropsychiatry and Clinical Neurosciences, 15, 67-73
12. Lövheim, H., Sandman, P. O., Kallin, K., Karlsson, S. and Gustafson, Y. (2006). Relationship between antipsychotic drug use and behavioral and psychological symptoms of dementia in old people with cognitive impairment living in geriatric care. International Psychogeriatrics, 18, 713-726. doi: 10.1017/ S1041610206003930 (Pubitemid 44623003)
13. Lövheim, H., Sandman, P.O., Kallin, K., Karlsson, S. and Gustafson, Y. (2008a). Symptoms of mental health and psychotropic drug use among old people living in geriatric care: changes between 1982 and 2000. International Journal of Geriatric Psychiatry, 23, 289-294. doi: 10.1002/gps.1876
14. Lövheim, H., Sandman, P. O., Karlsson, S. and Gustafson, Y. (2008b). Behavioral and psychological symptoms of dementia in relation to level of cognitive impairment. International Psychogeriatrics, 20, 777-789. doi: 10.1017/S1041610208006777 (Pubitemid 351704877)
15. Montagnier, D. et al. (2006). Evolution of prevalence of depressive symptoms and antidepressant use between 1988 and 1999 in a large sample of older French people: results from the Personnes Aǵees Quid Study. Journal of the American Geriatrics Society, 54, 1839-1845. doi: 10.1111/ j.1532-5415.2006.00969.x
16. Morgan, K. (2003). Sleep, aging, and late-life insomnia. In R. Tallis and H. Fillit (eds.), Brocklehurst's Textbook of Geriatric Medicine and Gerontology (pp. 1367-1380). London: Churchill Livingstone
17. Nygaard, H. A., Ruths, S., Straand, J. and Naik, M. (2004). Not less but different: psychotropic drug utilization trends in Norwegian nursing homes during a 12-year period: the Bergen District Nursing Home (BEDNURS) Study. Aging: Clinical and Experimental Research, 16, 277-282
18. O'Connor, D. W., Ames, D., Gardner, B. and King, M. (2009). Psychosocial treatments of psychological symptoms in dementia: a systematic review of reports meeting quality standards. International Psychogeriatrics, 21, 241-251
19. Ramasubbu, R. (2004). Antidepressant treatment-associated behavioural expression of hypomania: a case series. Progress in Neuro-psychopharmacology and Biological Psychiatry, 28, 1201-1207. doi: 10.1016/j.pnpbp.2004.06.015 (Pubitemid 40017639)
20. Robert, P. H. et al. (2005). Grouping for behavioral and psychological symptoms in dementia: clinical and biological aspects. Consensus paper of the European Alzheimer disease consortium. European Psychiatry, 20, 490-496, doi: 10.1016/j.eurpsy.2004.09.031 (Pubitemid 41681558)
21. Rochon, P. A. et al. (2008). Antipsychotic therapy and short-term serious events in older adults with dementia. Archives of Internal Medicine, 168, 1090-1096
22. Sandberg, O., Gustafson, Y., Brännström, B. and Bucht, G. (1998). Prevalence of dementia, delirium and psychiatric symptoms in various care settings for the elderly. Scandinavian Journal of Social Medicine, 26, 56-62
23. Sandman, P. O., Adolfsson, R., Norberg, A., Nyström, L. and Winblad, B. (1988). Long-term care of the elderly: a descriptive study of 3600 institutionalized patients in the county of Västerbotten, Sweden. Comprehensive Gerontology A, 2, 120-132
24. Schneider, L. S., Dagerman, K. S. and Insel, P. (2005). Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA, 294, 1934-1943
25. Shin, I. S., Carter, M., Masterman, D., Fairbanks, L. and Cummings, J. L. (2005). Neuropsychiatric symptoms and quality of life in Alzheimer disease. American Journal of Geriatric Psychiatry, 13, 469-474
26. Sink, K. M., Holden, K. F. and Yaffe, K. (2005). Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA, 293, 596-608 (Pubitemid 40171242)
27. Spigset, O. (1999). Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system. Drug Safety, 20, 277-287
28. Statistics Sweden (2007). Population Statistics. Population by Region, Marital Status, Age and Sex. Years 1968-2006. Örebro: Statistics Sweden
29. Tangwongchai, S. et al. (2008). Galantamine for the treatment of BPSD in Thai patients with possible Alzheimer's disease with or without cerebrovascular disease. American Journal of Alzheimer's Disease and Other Dementias, 23, 593-601. doi: 10.1177/1533317508320603
30. Testad, I., Aasland, A. M. and Aarsland, D. (2007). Prevalence and correlates of disruptive behavior in patients in Norwegian nursing homes. International Journal of Geriatric Psychiatry, 22, 916-921. doi: 10.1002/gps.1766 (Pubitemid 47455276)