Hydrogels based on carboxymethylcellulose and gelatin for inclusion and release of chloramphenicol

Journal of Bioactive and Compatible Polymers

Volumn 24, Issue 6, 2009, Pages 525-545

  Buhus, Gabriela ^a,b   Popa, Marcel ^a   Desbrieres, Jacques ^b  

^a GHEORGHE ASACHI TECHNICAL UNIVERSITY OF IASI   (Romania)

^b UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR   (France)

Author keywords

Carboxymethylcellulose gelatin hydrogel; Control by diffusion; Drug delivery; Interpenetrated interconnected network; Microbiological test

Indexed keywords

BIOMEDICAL APPLICATIONS; CARBOXYMETHYLCELLULOSE; CARBOXYMETHYLCELLULOSE/GELATIN HYDROGEL; CONTROLLED RELEASE; CROSS-LINKING DEGREE; CROSSLINKED; CROSSLINKING REACTION; GLUTARALDEHYDES; INTERPENETRATED- INTERCONNECTED NETWORK; MICROBIOLOGICAL TEST; NON-TOXICITY; POLYMER NETWORKS; SWELLING CAPACITIES;

ALDEHYDES; BIOCOMPATIBILITY; DIFFUSION; DRUG DELIVERY; FUNCTIONAL POLYMERS; GELATION; GELS; INTERCONNECTION NETWORKS; POLYMERS;

HYDROGELS;

CARBOXYMETHYLCELLULOSE; CHLORAMPHENICOL; GELATIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BIOCOMPATIBILITY; CONTROLLED STUDY; CROSS LINKING; DRUG ABSORPTION; DRUG DIFFUSION; DRUG RELEASE; HYDROGEL; INFRARED SPECTROSCOPY; NONHUMAN; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY;

EID: 70350512877     PISSN: 08839115     EISSN: 15308030     Source Type: Journal    
DOI: 10.1177/0883911509349687     Document Type: Article

References (55)

1. Kashyap, N., Kumar, N. and Kumar, M. (2005). Hydrogels for Pharmaceutical and Biomedical Applications, Critical Review in Therapeutic Drug Carrier Systems, 22: 107-149.
2. Peppas, N.A., Burns, P., Leobandung, W. and Ichikawa, H. (2000). Hydrogels in Pharmaceutical Formulations, European Journal of Pharmaceutics and Biopharmaceutics, 50: 27-46.
3. Young, S., Wong, M., Tabata, Y. and Mikos, A.G. (2005). Gelatin as a Delivery Vehicle for the Controlled Release of Bioactive Molecules, Journal of Controlled Release, 109: 256-274.
4. Qiu, Y. and Park, K. (2001). Environment-sensitive Hydrogels for Drug Delivery, Advances in Drug Delivery Review, 53: 321-339.
5. Koob, T.J. and Hernandez, D.J. (2003). Mechanical and Thermal Properties of Novel Polymerized NDGA-Gelatin Hydrogels, Biomaterials, 24: 1285-1292.
6. Bertram, U. and Bodmeier, R. (2006). In Situ Gelling, Bioadhesive Nasal Inserts for Extended Drug Delivery: In Vitro Characterization of a New Nasal Dosage Form, European Journal of Pharmaceutical Science, 27: 62-71.
7. Frokjaer, S. and Otzen, D.E. (2005). Protein Drug Stability: A Formulation Challenge, Nature Reviews Drug Discovery, 4: 298-306.
8. Cai, S., Liu, Y., Shu, X.Z. and Prestwich, G.D. (2005). Injectable Glycosaminoglycan Hydrogels for Controlled Release of Human Basic Fibroblast Growth Factor, Biomaterials, 26: 6054-6067.
9. Coviello, T., Matricardi, P., Marianecci, C. and Alhaique, F. (2007). Polysaccharide Hydrogels for Modified Release Formulations, Journal of Controlled Release, 119: 5-24. (Pubitemid 46561537)
10. Tã?nnesen, H.H. and Karlsen, J. (2002). Alginate in Drug Delivery Systems, Drug Development and Industrial Pharmacy, 28: 621-630.
11. Liew, C.V., Chan, L.W., Ching, A.L. and Heng, P.W.S. (2006). Evaluation of Sodium Alginate as Drug Release Modifier in Matrix Tablets, International Journal of Pharmacology, 309: 25-37.
12. Bhopatkar, D., Anal, A.K. and Stevens, W.F. (2005). Ionotropic Alginate Beads for Controlled Intestinal Protein Delivery: Effect of Chitosan and Barium Counterions on Entrapment and Release, Journal of Microencapsulation, 22: 91-100.
13. Liang, H.F., Hong, M.H., Ho, R.M., Chung, C.K., Lin, Y.H., Chen, C.H. et al. (2004). Novel Method using a Temperature-sensitive Polymer (Methylcellulose) to Thermally Gel Aqueous Alginate as a pH-sensitive Hydrogel, Biomacromolecules, 5: 1917-1925.
14. Hennink, W.E., Franssen, O., Van Dijk-Wolthuis, W.N.E. and Talsma, H. (1997). Dextran Hydrogels for the Controlled Release of Proteins, Journal of Controlled Release, 48: 107-114.
15. Fundueanu, G., Constantin, M., Esposito, E., Cortesi, R., Nastruzzi, C. and Menegatti, E. (2005). Cellulose Acetate Butyrate Microcapsules Containing Dextran Ion-exchange Resins as Self-propelled Drug Release System, Biomaterials, 26: 4337-4347.
16. Stubbe, B., Maris, B., Van Den Mooter, G., De Smedt, S.C. and Demeester, J. (2001). The In Vitro Evaluation of ĝ€?Azo Containing Polysaccharide Gels for Colon Delivery, Journal of Controlled Release, 75: 103-114.
17. Agnihotri, S.A. and Aminabhavi, T.M. (2005). Development of Novel Interpenetrating Network Gellan Gum-poly(vinyl alcohol) Hydrogel Microspheres for the Controlled Release of Carvedilol, Drug Development and Industrial Pharmacy, 31: 491-503.
18. Dumitriu, S. and Chornet, E. (1998). Inclusion and Release of Proteins from Polysaccharide-based Polyion Complexes, Advances in Drug Delivery Review, 31: 223-246.
19. Barbucci, R., Consumi, M., Lamponi, S. and Leone, G. (2003). Polysaccharides Based Hydrogels for Biological Applications, Macromolecular Symposium, 204: 37-58.
20. Ha, D.I., Lee, S.B., Chong, M.S., Lee, Y.M., Kim, S.Y. and Park, Y.H. (2006). Preparation of Thermo-responsive and Injectable Hydrogels Based on Hyaluronic Acid and Poly(N-isopropylacrylamide) and their Drug Release Behaviours, Macromolecular Research, 14: 87-93.
21. Kumari, K. and Kundu, P.P. (2007). Semiinterpenetrating Polymer Networks of Chitosan and L-alanine for Monitoring the Release of Chlorpheniramine Maleate, Journal of Applied Polymer Science, 103: 3751-3757.
22. Alvarez-Lorenzo, C., Concheiro, A., Dubovik, A.S., Grinberg, N.V., Burova, T.V. and Grinberg, V.Y. (2005). Temperature-sensitive Chitosan-poly (N-isopropylacrylamide) Interpenetrated Networks with Enhanced Loading Capacity and Controlled Release Properties, Journal of Controlled Release, 102: 629-641.
23. Guo, B.L. and Gao, Q.Y. (2007). Preparation and Properties of a pH/Temperature-responsive Carboxymethyl Chitosan/Poly(N-isopropylacrylamide) Semi-IPN Hydrogel for Oral Delivery of Drugs, Carbohydrate Research, 342: 2416-2422.
24. Soo, P.L., Cho, J., Grant, J., Ho, E., Piquette-Miller, M. and Allen, C. (2008). Drug Release Mechanism of Paclitaxel from a Chitosan-lipid Implant System: Effect of Swelling, Degradation and Morphology, European Journal of Pharmaceutics and Biopharmaceutics, 69: 149-157.
25. Davis, T.P. and Huglin, M.B. (1990). Effect of Composition on Properties of Copolymeric N-vinyl-2-pyrrolidone/Methyl Methacrylate Hydrogels and Organogels, Polymer, 31: 513-519.
26. Desai, N.P. and Hubbell, J.A. (1992). Surface Physical Interpenetrating Networks of Poly(ethylene-terephthalate) and Poly(ethylene oxide) with Biomedical Applications, Macromolecules, 25: 226-232.
27. Khare, A.R. and Peppas, N.A. (1993). Investigation of Hydrogel Water in Polyelectrolyte Gels using Differential Scanning Calorimetry, Polymer, 34: 4595-4800.
28. Choi, Y.S., Hong, S.R., Lee, Y.M., Song, K.W., Park, M.H. and Nam, Y.S. (1999). Studies on Gelatin-containing Artificial Skin: II. Preparation and Characterization of Cross-linked Gelatin-hyaluronate Sponge, Journal of Biomedical Materials Research, 48: 631-639.
29. Fujioka, K., Maeda, M., Hojo, T. and Sano, A. (1998). Protein Release from Collagen Matrices, Advanced Drug Delivery Reviews, 31: 247-266.
30. Balakrishnan, B. and Jayakrishnan, A. (2005). Self-cross-linking Biopolymers as Injectable In Situ Forming Biodegradable Scaffolds, Biomaterials, 26: 3941-3951.
31. Okino, H., Nakayama, Y., Tanaka, M. and Matsuda, T. (2002). In Situ Hydrogelation of Photocurable Gelatin and Drug Release, Journal of Biomedical Materials Research, 59: 233-245.
32. Changez, M., Koul, V. and Dinda, A.K. (2005). Efficacy of Antibiotics Loaded Interpenetrating Network (IPNs) Hydrogel Based on Poly(acrylic acid) and Gelatin for Treatment of Experimental Osteomyelitis: In Vivo Study, Biomaterials, 26: 2095-2104.
33. Yu, H. and Xiao, C. (2008). Synthesis and Properties of Novel Hydrogels from Oxidized Konjac Glucomannan Crosslinked Gelatin for In Vitro Drug Delivery, Carbohydrate Polymers, 72: 479-489.
34. Einerson, N.J., Stevens, K.R. and Kao, W.J. (2002). Synthesis and Physicochemical Analysis of Gelatin-based Hydrogels for Drug Carrier Matrices, Biomaterials, 24: 509-523.
35. Klemm, D., Philipp, B., Heinze, T., Heinze, U. and Wagenknecht, W. (1998). Comprehensive Cellulose Chemistry, Vol. 2, New York: Wiley-VCH Verlag.
36. Emeje, M.O., Kunle, O.O. and Ofoefule, S.I. (2006). Effect of the Molecular Size of Carboxymethylcellulose and some Polymers on the Sustained Release of Theophylline from a Hydrophilic Matrix, Acta Pharmaceutica, 56: 325-335.
37. Rokhade, A.P., Agnihotri, S.A., Patil, S.A., Mallikarjuna, N.N., Kulkarni, P.V. and Aminabhavi, T.M. (2006). Semi-interpenetrating Polymer Network Microspheres of Gelatin and Sodium Carboxymethyl Cellulose for Controlled Release of Ketorolac Tromethamine, Carbohydrate Polymers, 65: 243-252.
38. Available at: http://en.wikipedia.org/wiki/Total-Kjeldahl-Nitrogen
39. Alupei, I.C., Popa, M., Hamcerencu, M. and Abadie, J.M. (2002). Superabsorbant Hydrogels Based on Xanthan and Poly(vinyl alcohol). 1. The Study of the Swelling Properties, European Polymer Journal, 38: 2313-2320.
40. Available at: http://fr.wikipedia.org/wiki/Galose-Mueller-Hinton
41. Coates, J. (2000). Interpretation of Infrared Spectra: A Practical Approach, In: Mayers, R.A. (ed.), Encyclopedia of Chemistry, pp. 10815-10837, Chichester: John Wiley & Sons.
42. Mansur, H.S., Orefice, R.L., Pereira, M.M., Lobato, Z.I.P., Vasconcelos, W.L. and Machado, L.J.C. (2002). FTIR and UV-VIS Study of Chemically Engineered Biomaterial Surfaces for Protein Immobilization, Spectroscopy - An International Journal, 16: 351-336.
43. Nenitescu, C.D. (1980). Chimie Organica, Vol. 1, Ed. Didactica si Pedagogica Bucuresti.
44. Vollhardt, K.P.C. and Schore, N.E. (2004). Traitá De Chimie Organique. Aldehydes et Cetones: la Fonction Carbonyle, De Boeck Universitá, Bruxelles.
45. Davidson, R. and Sitting, M. (1962). Water Soluble Resins, New York: Reinhold Book Corporation.
46. Delgado, M., Spanka, C., Kerwin, L.D., Wentworth Jr, P. and Janka, K.D. (2002). A Tunable Hydrogel for Encapsulation and Controlled Release of Bioactive Proteins, Biomacromolecules, 3: 262-271.
47. Dumitriu, C.L., Popa, M., Vasiliu, S. and Sunel, V. (2004). Interpenetrated Nertwork-type Hydrogels Based on Gellan and Poly(vinyl alcohol) for Inclusion and Release of Cephotaxime, Journal of Macromolecular Science, Part A - Pure and Applied Chemistry: A, 41: 727-739.
48. Popa, M., Dumitriu, C.L. and Sunel, V. (2004). Interpenetrated Polymeric Networks Based on Gellan and Poly(vinyl alcohol), Polymer-plastics Technology and Engineering, 43: 1503-1516.
49. Popa, M., Bajan, N., Popa, M.I. and Popa, A.A. (2006). Diffusional System Based on Tolazoline Hydrochloride Included in a Reticulated Carboxymethylcellulose Hydrogel, Polymer-plastics Technology and Engineering, 45: 23-28.
50. Popa, M., Bajan, N., Popa, A.A. and Verestiuc, L. (2007). Novel Supports Based on Polysaccharides for Sustained Release of Isosorbide Dinitrate, Journal of Macromolecular Science, Part A - Pure and Applied Chemistry A, 44: 483-488.
51. Buhus, G., Popa, M., Peptu, C. and Desbrieres, J. (2007). Hydrogel Based on Carboxymethylcellulose and Poly(vinyl alcohol) for Controlled Loading and Release of Chlormaphenicol, Journal of Optoelectronics and Advanced Materials, 9: 3445-3453.
52. Peptu, C., Popa, M. and Antimisiaris, S.G. (2008). Release of Liposome-encapsulated Calcein from Liposome Entrapping Gelatin- carboxymethylcellulose Films: A Presentation of Different Possibilities, Journal of Nanoscience and Nanotechnology, 8: 1-10.
53. Bejenariu, A., Popa, M., Le Cerf, D. and Picton, L. (2008). Stiffness Xanthan Hydrogels: Synthesis, Swelling Characteristics and Controlled Release Properties, Polymer Bulletin, 61: 631-641.
54. Buiuc, D. (1992). Microbiologie Medicala, Ed. Didactica si Pedagogica, Bucuresti.
55. Rahal Jr, J.J. and Simberkoff, M.S. (1979). Bactericidal and Bacteriostatic Action of Chloramphenicol against Meningeal Pathogens, Antimicrobial Agents and Chemotherapy, 16: 13-18.