Fungal exposure endocrinopathy in sinusitis with growth hormone deficiency: Dennis-Robertson syndrome

Toxicology and Industrial Health

Volumn 25, Issue 10, 2009, Pages 669-680

  Dennis, Donald ^a   Robertson, David ^a   Curtis, Luke ^b   Black, Judson ^a  

^a PIEDMONT HOSPITAL   (United States)

^b Occupational Physician and Industrial Hygienist   (United States)

Author keywords

allergic fungal sinusitis (AFS); chronic rhinosinusitis (CRS); Fatigue; hypopituitarism

Indexed keywords

AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CEFAZOLIN; CIPROFLOXACIN; CLINDAMYCIN; CLOTRIMAZOLE; COTRIMOXAZOLE; ESTROGEN; GENTAMICIN; GROWTH HORMONE; IMMUNOGLOBULIN G; SOMATOMEDIN C; STEROID; TRICHOTHECENE; VORICONAZOLE;

ADULT; AGED; CAUSAL ATTRIBUTION; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CONTROLLED STUDY; CORTICOTROPIN DEFICIENCY; DENNIS ROBERTSON SYNDROME; ENDOCRINE DISEASE; ENDOSCOPY; ENVIRONMENTAL EXPOSURE; EVENING DOSAGE; FATIGUE; FEMALE; FUNGAL COLONIZATION; GROWTH HORMONE DEFICIENCY; HUMAN; HYPOPITUITARISM; IMMUNOGLOBULIN BLOOD LEVEL; INNATE IMMUNITY; INSULIN TOLERANCE TEST; MAJOR CLINICAL STUDY; MALE; RHINOSINUSITIS; VITAMIN SUPPLEMENTATION;

ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; ADULT; AGED; AIR MICROBIOLOGY; AIR POLLUTION, INDOOR; ANTIFUNGAL AGENTS; CHRONIC DISEASE; ENVIRONMENTAL EXPOSURE; FEMALE; FUNGI; GLUCOCORTICOIDS; GROWTH DISORDERS; HORMONE REPLACEMENT THERAPY; HUMAN GROWTH HORMONE; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SINUSITIS;

FUNGI;

EID: 70350508523     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233709348266     Document Type: Article

References (36)

1. Abdel-Haq H., Giacomelli S., Palmery M., Leone MG, Saso L., and Silvestrini B. (2000) Aflatoxins inhibit prolactin secretion in culture. Drug and Chemical Toxicology 23: 381-386.
2. Alkemade A., Friesma EC, Kuiper GG, et al. (2006) Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. European Journal of Endocrinology 154: 491-500.
3. Benninger MS, Desrosiers M., and Klossek JM (2006) Management of acute bacterial rhinosinusitis: current issues and future perspectives. International Journal of Clinical Practice 60: 190-200.
4. Benninger MS, Ferguson BJ, Hadley JA, et al. (2003) Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngology and Head and Neck Surgery 129: S1-S32.
5. Bhattacharyya N. (2003) The economic burden and symptom manifestation of chronic rhinosinusitis. American Journal of Rhinology 7: 27-32.
6. Breuel KF, Kougias P., Rice P., et al. (2004) Anterior pituitary cells express pattern recognition receptors for fungal glucans: implications for Neuroendocrine immune involvement in response to fungal infections. Neuroimmunomodulation 11: 1-9.
7. Campbell A., Thrasher J., Gray M., and Vojdani A. (2004) Molds and mycotoxins: effects on the neurological and immunological systems in humans. Advances in Applied Microbiology 55: 375-406.
8. Chambers DW, Davis WE, Cook PR, Nishioka GJ, and Rudman DT (1997) Long-term outcome-analysis of functional endoscopic sinus surgery: correlation of symptoms with endoscopic examination findings and potential prognostic variables. The Laryngoscope 107: 504-510.
9. Chester AC (2003) Symptoms of rhinosinusitis in patients with unexplained chronic fatigue or body pain. Archives of Internal Medicine 63: 1832-1836.
10. Collins TF, Sprando RL, Black TN, Olejnik N., Eppley RM, Alam HZ, Rorie J., Ruggles DI (2006) Effects of zearaleonone on in utero development in rats. Food and Chemical Toxicology 44: 1455-1465.
11. Conte LJ, Holtzberg N. (1996) Functional endoscopic sinus surgery, symptomatic relief: a patient perspective. American Journal of Rhinology 10: 135-140.
12. Dennis D. (2003) Chronic sinusitus: defective T-cells responding to superantigens, treated by reduction of fungi in the nose and air. Archives of Environmental Health 58: 433-441.
13. Fliers E., Unmehopa UA, and Alkemade A. (2006) Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland. Molecular and Cellular Endocrinology 251: 1-8.
14. Fisk WL, Lei-Gomez Q., and Mendell MJ (2007). Meta-analyses of the associations of the respiratory health effects of dampness and mold in homes. Indoor Air 17: 284-296.
15. Gray MR, Thrasher JD, and Crago R. (2003) Mixed mold mycotoxicosis: immunological changes in humans following exposure in water-damaged buildings. Archives of Environmental Health 58: 410-420.
16. Health on the Net Foundation. (1995) Allergy Glossary. Available at: http://www.hon.ch/Library/Theme/Allergy/Glossary/allergy.html
17. Hoffman SR, Mahoney MC, Chmiel JF, Stinziano GD, and Hoffman KN (1993) Symptom relief after endoscopic sinus surgery: an outcomes-based study. Ear, Nose, & Throat Journal 72: 413-420.
18. Krakauer T. (1999) Immune response to staphyloccal superantigens. Immunologic Research 20: 163-173.
19. Liiv I., Teesalu K., Peterson P., Perheentupa J., Uibo R. (2007) Identification of the 49-kDa Autoantigen Associated with Lymphocytic Hypophysitis as α-Enolase. The Journal of Clinical Endocrinology & Metabolism 87: 752-757.
20. Mathioudakis N., Salvatori R. (2008) Adult-onset growth hormone deficiency: causes, complications and treatment options. Current Opinion in Endocrinology, Diabetes, and Obesity 2008: 352-358.
21. Monson JP (2008) Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical practice Guideline. Clinics in Endocrinology and Metabolism 91: 1621-1634.
22. O’Dwyer DT, McElduff P., Peterson P., Perheentupa J., and Crock PA (2007) Pituitary autoantibodies in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Acta Biomedica 78: 248-254.
23. Ponikau JU, Sherris DA, Kern EB, et al. (1999) The diagnosis and incidence of allergic fungal sinusitis. Mayo Clinic Proceedings 74: 877-884.
24. Ponikau JU, Sherris DA, Kita H., and Kern EB (2002). Intranasal antifungal treatment in 51 patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology 110: 862-866.
25. Ponikau JU, Shin SH, Sherris DA, et al. (2004) Chronic rhinosinusitis: an enhanced immune response to ubiquitous airborne fungi. Journal of Allergy and Clinical Immunology 114: 1369-1375.
26. Rees DA (2005) Folliculostellate cells: what are they? Endocrine Abstracts 10: S31.
27. Ricchetti A., Landis BN, Maffioli A., Giger R., Zeng C., and Lacroix JS (2002) Effect of anti-fungal nasal lavage with amphotericin B on nasal polyposis. The Journal of Laryngology and Otology 116: 261-263.
28. Schubert MS (2001). A superantigen hypothesis for the pathogenesis of chronic hypertrophic rhinosinusitis, allergicfungal sinusitis, and related disorders. Annals of Allergy, Asthma & Immunology 4: 181-187.
29. Shao PL, Haung LM, and Hsueh PR (2007) Recent advances and challenges in the treatment of invasive fungal infections. International Journal of Antimicrobial Agents 30: 487-495.
30. Sherris DA, Ponikau JU, Weaver A., Frigas E., and Kita H. (2005). Treatment of chronic rhinosinusitis with intranasal amphotericin B: A prospective, randomized, placebo-controlled trial. Journal of Allergy and Clinical Immunology 115: 125-131.
31. Stochholm K., Gravholt CH, Laursen T., et al. (2006) Incidence of GH deficiency - a nationwide survey. European Journal of Endocrinology 155: 61-71.
32. Stochholm K., Gravholt CH, Laursen T., et al. (2007) Mortality and GH deficiency: a nationwide survey. European Journal of Endocrinology 157: 9-18.
33. Stochholm K., Laursen T., Green A., et al. (2008). Morbidity and GH deficiency: a nationwide study. European Journal of Endocrinology 158: 447-457.
34. Takahashi M., Shibutani M., Sugita-Konishi Y., Inoue K., Woo GH, Fujimoto H., Hirose M. (2007) A 90-day sub-chronic toxicity study of nivaleonol, a tricothesene mycotoxin, in F344 rates. Food and Chemical Toxicology 46: 125-135.
35. Warnock D. (2006) Correlation of MIC with Outcome for Candida Species Tested against Voriconazole: Analysis and Proposal for Interpretive Breakpoints. Journal of Clinical Microbiology 44: 819-826.
36. Winstead W., Barnett SN (1998) Impact of endoscopic sinus surgery on global health outcomes: a perception study. Otolaryngology and Head and Neck Surgery 119: 486-491.