Enzyme-assisted physicochemical enantioseparation processes - Part III: Overcoming yield limitations by dynamic kinetic resolution of asparagine via preferential crystallization and enzymatic racemization

Biotechnology and Bioengineering

Volumn 104, Issue 6, 2009, Pages 1235-1239

  Würges, Kerstin ^a   Petruševska Seebach, Katerina ^b   Elsner, Martin P ^b   Lütz, Stephan ^a,c  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Amino acid racemase; Asparagine; Dynamic kinetic resolution; In situ racemization; Integrated enantioseparation process; Preferential crystallization; Production of L amino acids

Indexed keywords

ASPARAGINE; DYNAMIC KINETIC RESOLUTION; IN SITU RACEMIZATION; INTEGRATED ENANTIOSEPARATION PROCESS; PREFERENTIAL CRYSTALLIZATION;

AMINATION; AMINES; AMINO ACIDS; ENZYMES; ESCHERICHIA COLI; ORGANIC ACIDS;

CRYSTALLIZATION;

ASPARAGINE; RACEMASE;

ARTICLE; CRYSTALLIZATION; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME MECHANISM; ESCHERICHIA COLI; KINETICS; LYOPHILISATE; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN EXPRESSION; RACEMIZATION;

AMINO ACID ISOMERASES; ASPARAGINE; CRYSTALLIZATION; ESCHERICHIA COLI; GENE EXPRESSION; PSEUDOMONAS PUTIDA; STEREOISOMERISM;

EID: 70350508285     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22498     Document Type: Article

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