Rationale for Monitoring Cyclosporine Concentration at 2 Hours After Administration in Infants Posttransplantation

Transplantation Proceedings

Volumn 41, Issue 8, 2009, Pages 3333-3334

  Furlan, V ^a   Lykavieris, P ^a   Maubert, M A ^a   Habes, D ^a   Debray, D ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EXPOSURE; FEMALE; GRAFT SURVIVAL; HUMAN; INFANT; LIVER BIOPSY; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; CYCLOSPORINE; DRUG MONITORING; EMULSIONS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; INTESTINAL ABSORPTION; LIVER TRANSPLANTATION; MALE; METABOLIC CLEARANCE RATE;

EID: 70350504451     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.08.040     Document Type: Article

References (6)

1. Dunn S.P., Cooney G.F., Kulinsky A., et al. Absorption characteristics of a microemulsion formulation of cyclosporine in de novo pediatric liver transplant recipients. Transplantation 60 (1995) 1438
2. Frauca E., Diaz M.C., de la Vega, et al. Cyclosporine monitoring in the early post-transplant period in pediatric liver transplant recipients. Pediatr Transplant 11 (2007) 530
3. Weber L.T., Armstrong W., Shipkova M., et al. Cyclosporin A absorption profiles in pediatric renal transplant recipients predict the risk of acute rejection. Ther Drug Monit 26 (2004) 415
4. Kelly D., Jara P., Rodeck B., et al. Tacrolimus and steroids versus cyclosporine microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trial. Lancet 364 (2004) 1054
5. Whitington P.F., Emond J.C., Whitington S.H., et al. Small-bowel length and the dose of cyclosporine in children after liver transplantation. N Engl J Med 322 (1990) 733
6. Fakhoury M., Litalien C., Medard Y., et al. Localization and mRNA expression of CYP3A and P- glycoprotein in human duodenum as a function of age. Drug Metab Dispos 33 (2005) 1603