Up-regulation of osteolytic mediators in human osteosarcoma cells stimulated with nicotine

Journal of Periodontal Research

Volumn 44, Issue 6, 2009, Pages 760-766

  Ho, Y C ^b   Yang, S F ^c   Huang, F M ^a   Chang, Y C ^a,d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b School of Applied Chemistry

^c Institute of Medicine

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Nicotine; Osteosarcoma cells; Pro inflammatory cytokines; Proteolytic enzymes; Receptor activator of nuclear factor B ligand (RANKL)

Indexed keywords

CASEIN; GELATINASE; GELATINASE A; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 8; MMP2 PROTEIN, HUMAN; NICOTINE; NICOTINIC AGENT; OSTEOCLAST DIFFERENTIATION FACTOR; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; DOSE RESPONSE; DRUG EFFECT; HUMAN; MOLECULAR WEIGHT; OSTEOLYSIS; OSTEOSARCOMA; PATHOPHYSIOLOGY; TIME; TUMOR CELL LINE; UPREGULATION;

CASEINS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GELATINASES; HUMANS; INTERLEUKIN-1; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MOLECULAR WEIGHT; NICOTINE; NICOTINIC AGONISTS; OSTEOLYSIS; OSTEOSARCOMA; RANK LIGAND; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; UP-REGULATION;

EID: 70350501701     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2008.01188.x     Document Type: Article

References (39)

1. Feldman RS, Bravacos JS, Rose CL. Association between smoking different tobacco products and periodontal disease index. J Periodontol 1983 54 : 481 487.
2. Bergstrom J, Eliasson S, Preber H. Cigarette smoking and periodontal bone loss. J Periodontol 1994 65 : 540 550.
3. Cuff MJ, McQuade MJ, Scheidt MJ, Sutherland DE, Van Dyke TE. The presence of nicotine on root surfaces of periodontally diseased teeth in smokers. J Periodontol 1989 60 : 564 569.
4. McGuire JR, McQuade MJ, Rossman JA et al. Cotinine in saliva and gingival crevicular fluid of smokers with periodontal disease. J Periodontol 1989 60 : 176 181.
5. Chang YC, Lii CK, Tai KW, Chou MY. Adverse effects of arecoline and nicotine on human periodontal ligament fibroblasts in vitro. J Clin Periodontol 2001 28 : 277 282.
6. Chang YC, Huang FM, Tai KW, Yang LC, Chou MY. Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro. J Periodont Res 2002 37 : 279 285.
7. Chang YC, Hsieh YS, Lii CK, Huang FM, Tai KW, Chou MY. Induction of c-fos expression by nicotine in human periodontal ligament fibroblasts is related to cellular thiol levels. J Periodont Res 2003 38 : 44 50.
8. Chang YC, Tsai CH, Yang SH, Liu CM, Chou MY. Induction of cyclooxygenase-2 mRNA and protein expression in human gingival fibroblasts stimulated with nicotine. J Periodont Res 2003 38 : 496 501.
9. Ho YC, Chang YC. Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts. Acta Pharmacol Sin 2006 27 : 409 413.
10. Chang YC, Lai CC, Lin LF, Ni WF, Tsai CH. The upregulation of heme oxygenase-1 expression in human gingival fibroblasts stimulated with nicotine. J Periodont Res 2005 40 : 252 257.
11. Huang CY, Chen JH, Tsai CH, Kuo WW, Liu JY, Chang YC. Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine. J Periodont Res 2005 40 : 176 181.
12. Listgarten MA. Nature of periodontal diseases: pathogenic mechanisms. J Periodont Res 1987 22 : 172 178.
13. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 1994 55 : 97 179.
14. Dongari-Bagtzoglou AI, Ebersole JL. Increased presence of interleukin-6 (IL-6) and IL-8 secreting fibroblast subpopulations in adult periodontitis. J Periodontol 1998 69 : 899 910.
15. Fuller K, Wong B, Fox S, Choi Y, Chambers TJ. Trance is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclast. J Exp Med 1998 188 : 997 1001.
16. Lu HK, Chen YL, Chang HC, Li CL, Kuo MYP. Identification of the OPG-RANKL system in gingival crevicular fluid and tissue of patients with chronic periodontitis. J Periodont Res 2006 41 : 354 360.
17. Soell M, Elkaim R, Tenenbeam H. Cathepsin C, matrix metalloproteinases, and their tissue inhibitors in gingival and gingival crevicular fluid from periodontitis affected patients. J Dent Res 2002 81 : 174 178.
18. Ejeil AL, Igondjo-Tchen S, Ghomrasseni S, Pellat B, Godeau G, Gogly B. Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva. J Periodontol 2003 74 : 188 195.
19. Vassalli JD, Sappino AP, Belim D. The plasminogen activator-plasmin system. J Clin Invest 1991 88 : 1067 1072.
20. Daci E, Udagawa N, Martin TJ, Bouillon R, Carmeliet G. The role of the plasminogen system in bone resorption in vitro. J Bone Miner Res 1999 14 : 946 952.
21. Xia Y, Bunn CL, Bartold PM. Detection of tissue plasminogen activator and plasminogen activator inhibitor in gingival crevicular fluid from healthy, gingivitis and periodontitis patients. J Clin Periodontol 2002 27 : 149 156.
22. Olofsson A, Maysson L, Kinnby B. Plasminogen activating capacity in gingival fluid from deteriorating and stable periodontal pockets. J Periodont Res 2002 37 : 60 65.
23. Chang YC, Chu SC, Yang SF, Hsieh YS, Yang LC, Huang FM. Examination of the signal transduction pathways leading to activation of gelatinolytic activity by interleukin-1α and Porphyromonas gingivalis in human osteosarcoma cells. J Periodont Res 2004 39 : 168 174.
24. Chang YC, Ho YC, Chou LSS, Chou MY, Huang FM. Signal transduction pathways involved in the stimulation of tissue type plasminogen activator by interleukin-1α and Porphyromonas gingivalis in human osteosarcoma cells. J Periodont Res 2006 41 : 374 380.
25. Grossi SG, Genco RJ, Machtei EE, Ho AW, Koch G, Dunford R. Assessment of risk for periodontal disease II. Risk indicators for alveolar bone loss. J Periodontol 1995 66 : 23 29.
26. Jansson LE, Hagstrom KE. Relationship between compliance and periodontal treatment outcome in smokers. J Periodontol 2002 73 : 602 607.
27. Yang LC, Huang FM, Lin CS, Liu CM, Lai CC, Chang YC. Induction of interleukin-8 gene expression by black-pigmented Bacteroides in human pulp fibroblasts and osteoblasts. Int Endod J 2003 36 : 774 779.
28. Giannopoulou C, Kamma JJ, Mombelli A. Effect of inflammation, smoking and stress on gingival crevicular fluid cytokine level. J Clin Periodontol 2003 30 : 145 153. (Pubitemid 38019410)
29. Wendell KJ, Stein SH. Regulation of cytokine production in human gingival fibroblasts following treatment with nicotine and lipopolysaccharide. J Periodontol 2001 72 : 1038 1044.
30. Almasri A, Wisithphrom K, Windsor LJ, Olson B. Nicotine and lipopolysaccharide affect cytokine expression from gingival fibroblasts. J Periodontol 2007 78 : 533 541.
31. Rawlinson A, Grummitt JM, Walsh TF, Ian Douglas CW. Interleukin 1 and receptor antagonist levels in gingival crevicular fluid in heavy smokers versus nonsmokers. J Clin Periodontol 2003 30 : 42 48.
32. Cesar-Neto JB, Duarte PM, de Oliveira MCG, Tambeli CH, Sallum EA, Nociti FH Jr. Smoking modulates interleukin-6:interleukin-10 and RANKL:osteoprotegerin ratios in the periodontal tissues. J Periodont Res 2007 42 : 184 191.
33. Nordskog BK, Blixt AD, Morgan WT, Fields WR, Hellmann GM. Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. Cardiovasc Toxicol 2003 3 : 101 117.
34. Zhang S, Day I, Ye S. Nicotine induced changes in gene expression by human coronary artery endothelial cells. Atherosclerosis 2001 154 : 277 283.
35. Zhou J, Olson BL, Windsor LJ. Nicotine increases the collagen-degrading ability of human gingival fibroblasts. J Periodont Res 2007 42 : 228 235.
36. Birkedal-Hansen H. Role of cytokines and inflammatory mediators in tissue destruction. J Periodont Res 1993 28 : 500 510.
37. Fukushima H, Jimi E, Okamoto F, Motokawa W, Okabe K. IL-1-induced receptor activator of NFkappaB ligand in human periodontal ligament cells involves ERK-dependent PGE2 production. Bone 2005 36 : 267 275.
38. Krall EA, Dawson-Hughes B. Smoking and bone loss among postmenopausal women. J Bone Miner Res 1991 6 : 331 338.
39. Ramp WK, Lenz LG, Galvin RJ. Nicotine inhibits collagen synthesis and alkaline phosphatase activity, but stimulates DNA synthesis in osteoblast-like cells. Proc Soc Exp Biol Med 1991 197 : 36 43.