Can hepatocellular cancer screening increase the proportion of long-term survivors?

Hepato-Gastroenterology

Volumn 56, Issue 93, 2009, Pages 1152-1156

  Gannon, Christopher J ^a   Izzo, Francesco ^b   Aloia, Thomas A ^c   Pignata, Sandro ^b   Nasti, Guglielmo ^b   Vallone, Paolo ^b   Orlando, Raffaele ^b   Scordino, Fabrizio ^b   Curley, Steven A ^d  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c HOUSTON METHODIST HOSPITAL   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cirrhosis; Curative; Hepatitis; Radiofrequency ablation; Resection

Indexed keywords

ALCOHOL; ALPHA FETOPROTEIN;

ADULT; ARTICLE; CANCER SCREENING; CHRONIC HEPATITIS; CONTROLLED STUDY; DISEASE SEVERITY; ECHOGRAPHY; FEMALE; FOLLOW UP; HEPATITIS B; HEPATITIS C; HEPATITIS VIRUS; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER RESECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; SURVIVOR; AGED; CHI SQUARE DISTRIBUTION; LIVER TUMOR; MASS SCREENING; METABOLISM; MIDDLE AGED; SURVIVAL RATE; TUMOR RECURRENCE; VIROLOGY;

ADULT; AGED; AGED, 80 AND OVER; ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; CHI-SQUARE DISTRIBUTION; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; LIVER NEOPLASMS; MASS SCREENING; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; SURVIVAL RATE; SURVIVORS; ULTRASONOGRAPHY;

EID: 70350498717     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Steward BW, Kleihues P, International Agency for Research on Cancer: World cancer report. Lyon: IARC Press, 2003; 351.
2. Perz JF, Armstrong GL, Farrington LA, Hutin YJ, Bell BP: The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 2006; 45:529-538. (Pubitemid 44307383)
3. Cha CH, Ruo L, Fong Y, Jarnagin WR, Shia J, Blumgart LH, et al.: Resection of hepatocellular carcinoma in patients otherwise eligible for transplantation. Ann Surg 2003; 238:315-321; discussion 321-313.
4. Fong Y, Sun RL, Jarnagin W, Blumgart LH: An analysis of 412 cases of hepatocellular carcinoma at a Western center. Ann Surg 1999;229:790-799; discussion 799-800.
5. Liu JH, Chen PW, Asch SM, Busuttil RW, Ko CY: Surgery for hepatocellular carcinoma: does it improve survival? Ann Surg Oncol 2004;11:298-303. (Pubitemid 40486770)
6. Ng KK, Vauthey JN, Pawlik TM, Lauwers GY, Regimbeau JM, Belghiti J, et al.: Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database. Ann Surg Oncol 2005;12:364-373.
7. Poon RT, Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK, et al.: Extended hepatic resection for hepatocellular carcinoma in patients with cirrhosis: is it justified? Ann Surg 2002;236:602-611. (Pubitemid 35246892)
8. Poon RT, Fan ST, Lo CM, Liu CL, Wong J: Difference in tumor invasiveness in cirrhotic patients with hepatocellular carcinoma fulfilling the Milan criteria treated by resection and transplantation: impact on long-term survival. Ann Surg 2007;245:51-58. (Pubitemid 46035435)
9. Minagawa M, Ikai I, Matsuyama Y, Yamaoka Y, Makuuchi M: Staging of hepatocellular carcinoma: assessment of the Japanese TNM and AJCC/UICC TNM systems in a cohort of 13,772 patients in Japan. Ann Surg 2007;245:909-922. (Pubitemid 46809293)
10. Barazani Y, Hiatt JR, Tong MJ, Busuttil RW: Chronic viral hepatitis and hepatocellular carcinoma. World J Surg 2007;31:1245-1250.
11. Chen TH, Chen CJ, Yen MF, Lu SN, Sun CA, Huang GT, et al.: Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan. Int J Cancer 2002;98:257-261. (Pubitemid 34150810)
12. Mok TS, Yeo W, Yu S, Lai P, Chan HL, Chan AT, et al.: An intensive surveillance program detected a high incidence of hepatocellular carcinoma among hepatitis B virus carriers with abnormal alpha-fetoprotein levels or abdominal ultrasonography results. J Clin Oncol 2005;23:8041-8047. (Pubitemid 46657406)
13. Ren FY, Piao XX, Jin AL: Efficacy of ultrasonography and alpha-fetoprotein on early detection of hepatocellular carcinoma. World J Gastroenterol 2006;12:4656-4659.
14. Sangiovanni A, Del Ninno E, Fasani P, De Fazio C, Ronchi G, Romeo R, et al.: Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance. Gastroenterology 2004;126:1005-1014. (Pubitemid 38451172)
15. Yuen MF, Lai CL: Screening for hepatocellular carcinoma: survival benefit and cost-effectiveness. Ann Oncol 2003;14:1463-1467.
16. Borger C: Health Spending Projections Through 2015: Changes on the Horizon. In: Health Affairs Web Exclusive 2006.
17. Okuda K, Ohtsuki T, Obata H, Tomimatsu M, Okazaki N, Hasegawa H, et al.: Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 1985;56:918-28. (Pubitemid 15228292)
18. Stuart KE, Anand AJ, Jenkins RL: Hepatocellular carcinoma in the United States. Prognostic features, treatment outcome, and survival. Cancer 1996; 77:2217-22. (Pubitemid 26162412)
19. Llovet JM, Bustamanta J, Castells A, Vilana R, Ayuso Mdel C, Sala M, et al.: Natural history of untreated nonsurgical hepatocellular carcinoma:rationale for the design and evaluation of therapeutic trials. Hepatology 1999; 29:62-7. (Pubitemid 29023987)
20. Cancer of the Liver Program (CLIP) investigators: A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients. Hepatology 1998;28:751-5.
21. Changchien CS, Chen CL, Yen YH, Wang JH, Hu TH, Lee CM, et al.: Analysis of 6381 hepatocellular carcinoma patients in southern Taiwan: prognostic features, treatment outcome, and survival. J Gastroenterol 2008;43:159-70.
22. Sarpel U, Schwartz M: Liver transplantation for hepatocellular carcinoma. Hepatol Res 2007;37:S264-266.
23. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, et al.: Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334: 693-699. (Pubitemid 26079803)
24. Fattovich G, Stroffolini T, Zagni I, Donato F: Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology 2004;127:S35-50. (Pubitemid 39423368)