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Volumn 5, Issue 11, 2009, Pages 611-612

Time to rethink immunosuppression by mTOR inhibitors?

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; RAPAMYCIN; TACROLIMUS; DRUG DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

EID: 70350495363     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2009.168     Document Type: Short Survey
Times cited : (8)

References (10)
  • 1
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    • MTOR regulates memory CD8 T-cell differentiation
    • Araki, K. et al. mTOR regulates memory CD8 T-cell differentiation. Nature 460, 108-112 (2009).
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    • Araki, K.1
  • 2
    • 67650096912 scopus 로고    scopus 로고
    • Enhancing CD8 T-cell memory by modulating fatty acid metabolism
    • Pearce, E. L. et al. enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460, 103-107 (2009).
    • (2009) Nature , vol.460 , pp. 103-107
    • Pearce, E.L.1
  • 3
    • 50649102202 scopus 로고    scopus 로고
    • Sirolimus early graft nephrotoxicity: Clinical and experimental data
    • Pallet, N., Thervet, E., Legendre, C. & Anglicheau D. sirolimus early graft nephrotoxicity: clinical and experimental data. Curr. Drug. Saf. 1, 179-187 (2006).
    • (2006) Curr. Drug. Saf. , vol.1 , pp. 179-187
    • Pallet, N.1    Thervet, E.2    Legendre, C.3    Anglicheau, D.4
  • 4
    • 37349034394 scopus 로고    scopus 로고
    • Reduced exposure to calcineurin inhibitors in renal transplantation
    • Ekberg, H. et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N. Engl. J. Med. 357, 2562-2575 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 2562-2575
    • Ekberg, H.1
  • 5
    • 53449096010 scopus 로고    scopus 로고
    • Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma
    • Barozzi, P. et al. Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma. Transplantation 86, 738-744 (2008).
    • (2008) Transplantation , vol.86 , pp. 738-744
    • Barozzi, P.1
  • 6
    • 45449112352 scopus 로고    scopus 로고
    • Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: A pooled analysis of clinical trials
    • Demopoulos, L. et al. Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials. Transplant. Proc. 40, 1407-1410 (2008).
    • (2008) Transplant. Proc. , vol.40 , pp. 1407-1410
    • Demopoulos, L.1
  • 7
    • 62049084947 scopus 로고    scopus 로고
    • Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    • Jagannath, C. et al. Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat. Med. 15, 267-276 (2009).
    • (2009) Nat. Med. , vol.15 , pp. 267-276
    • Jagannath, C.1
  • 8
    • 54949109311 scopus 로고    scopus 로고
    • The TsC-mTOR signaling pathway regulates the innate inflammatory response
    • weichhart, T. et al. The TsC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29, 565-577 (2008).
    • (2008) Immunity , vol.29 , pp. 565-577
    • Weichhart, T.1
  • 9
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    • The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
    • Delgoffe, G. M. et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity 30, 832-844 (2009).
    • (2009) Immunity , vol.30 , pp. 832-844
    • Delgoffe, G.M.1
  • 10
    • 37349080895 scopus 로고    scopus 로고
    • Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury
    • Ruggenenti, P. et al. sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury. Transplantation 84, 956-964 (2007).
    • (2007) Transplantation , vol.84 , pp. 956-964
    • Ruggenenti, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.