Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization

BMC Medical Genetics

Volumn 10, Issue , 2009, Pages 106-

  Shin, Jeong Ah ^a   Chang, Hun S ^b   Park, Se Min ^a   Jang, An Soo ^a   Park, Sung W ^a   Park, Jong S ^a   Uh, Soo Taek ^a   Il Lim, Gune ^a   Rhim, Taiyoun ^c   Kim, Mi Kyeong ^d   Choi, Inseon S ^e   Chung, Il Y ^f   Park, Byung L ^g   Shin, Hyoung D ^g,h   Park, Choon Sik ^a  

^a Soonchunhyang University   (South Korea)

^b Korea University   (South Korea)

^c Hanyang University   (South Korea)

^d Chungbuk National University College of Medicine   (South Korea)

^e Chonnam National University Medical School   (South Korea)

^f Hanyang University   (South Korea)

^g SNP Genetics Inc   (South Korea)

^h Sogang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYSTEINYL LEUKOTRIENE RECEPTOR 2; ENHANCED GREEN FLUORESCENT PROTEIN; LEUKOTRIENE RECEPTOR; MESSENGER RNA; NUCLEAR FACTOR; UNCLASSIFIED DRUG; LUCIFERASE;

3' UNTRANSLATED REGION; ARTICLE; ASTHMA; B LYMPHOCYTE; BINDING SITE; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HAPLOTYPE; HUMAN; HUMAN CELL; MESSENGER RNA SYNTHESIS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; RNA STABILITY; SINGLE NUCLEOTIDE POLYMORPHISM; BIOSYNTHESIS; CELL LINE; CHEMICALLY INDUCED DISORDER; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENETIC PREDISPOSITION; GENETICS;

HUMAN HERPESVIRUS 4;

ASPIRIN; ASTHMA; CELL LINE; DRUG HYPERSENSITIVITY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LUCIFERASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RECEPTORS, LEUKOTRIENE; RNA STABILITY; RNA, MESSENGER;

EID: 70350493704     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-10-106     Document Type: Article

References (25)

1. Samter M, Beers RF. Concerning the nature of intolerance to aspirin. J Allergy 1967, 40(5):281-293. 10.1016/0021-8707(67)90076-7, 5235203.
2. Sousa AR, Parikh A, Scadding G, Corrigan CJ, Lee TH. Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis. N Engl J Med 2002, 347(19):1493-1499. 10.1056/NEJMoa013508, 12421891.
3. Picado C. Aspirin-intolerant asthma: role of cyclo-oxygenase enzymes. Allergy 2002, 57(Suppl 72):58-60. 10.1034/j.1398-9995.57.s72.14.x, 12144557.
4. Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G. Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. Br Med J 1975, 1(5949):67-69. 10.1136/bmj.1.5949.67, 1672199, 1109660.
5. Szczeklik A. The cyclooxygenase theory of aspirin-induced asthma. Eur Respir J 1990, 3(5):588-593.
6. Henderson WR. The role of leukotrienes in inflammation. Ann Intern Med 1994, 121(9):684-697.
7. Drazen JM, Israel E, O'Byrne PM. Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med 1999, 340(3):197-206. 10.1056/NEJM199901213400306, 9895400.
8. Leff AR. Regulation of leukotrienes in the management of asthma: biology and clinical therapy. Annu Rev Med 2001, 52:1-14. 10.1146/annurev.med.52.1.1, 11160764.
9. Hui Y, Funk CD. Cysteinyl leukotriene receptors. Biochem Pharmacol 2002, 64(11):1549-1557. 10.1016/S0006-2952(02)01357-6, 12429344.
10. Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, Im DS, Stocco R, Bellefeuille JN, Abramovitz M, Cheng R. Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 2000, 275(39):30531-30536. 10.1074/jbc.M003490200, 10851239.
11. Coleman RA, Eglen RM, Jones RL, Narumiya S, Shimizu T, Smith WL, Dahlen SE, Drazen JM, Gardiner PJ, Jackson WT. Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature. Adv Prostaglandin Thromboxane Leukot Res 1995, 23:283-285.
12. Labat C, Ortiz JL, Norel X, Gorenne I, Verley J, Abram TS, Cuthbert NJ, Tudhope SR, Norman P, Gardiner P. A second cysteinyl leukotriene receptor in human lung. J Pharmacol Exp Ther 1992, 263(2):800-805.
13. Walch L, Norel X, Gascard JP, Brink C. Cysteinyl-leukotriene receptors in pulmonary vessels. J Physiol Pharmacol 1999, 50(4):567-573.
14. Mita H, Hasegawa M, Saito H, Akiyama K. Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. Clin Exp Allergy 2001, 31(11):1714-1723. 10.1046/j.1365-2222.2001.01184.x, 11696047.
15. Mellor EA, Frank N, Soler D, Hodge MR, Lora JM, Austen KF, Boyce JA. Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R. Proc Natl Acad Sci USA 2003, 100(20):11589-11593. 10.1073/pnas.2034927100, 208802, 13679572.
16. Early SB, Barekzi E, Negri J, Hise K, Borish L, Steinke JW. Concordant modulation of cysteinyl leukotriene receptor expression by IL-4 and IFN-gamma on peripheral immune cells. Am J Respir Cell Mol Biol 2007, 36(6):715-720. 10.1165/rcmb.2006-0252OC, 2720145, 17272825.
17. Duroudier NP, Tulah AS, Sayers I. Leukotriene pathway genetics and pharmacogenetics in allergy. Allergy 2009, 64(6):823-839. 10.1111/j.1398-9995.2009.02015.x, 19416143.
18. Daniels SE, Bhattacharrya S, James A, Leaves NI, Young A, Hill MR, Faux JA, Ryan GF, le Souef PN, Lathrop GM. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996, 383(6597):247-250. 10.1038/383247a0, 8805698.
19. Kimura K, Noguchi E, Shibasaki M, Arinami T, Yokouchi Y, Takeda K, Yamakawa-Kobayashi K, Matsui A, Hamaguchi H. Linkage and association of atopic asthma to markers on chromosome 13 in the Japanese population. Hum Mol Genet 1999, 8(8):1487-1490. 10.1093/hmg/8.8.1487, 10400996.
20. Park JS, Chang HS, Park CS, Lee JH, Lee YM, Choi JH, Park HS, Kim LH, Park BL, Choi YH. Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics. Pharmacogenet Genomics 2005, 15(7):483-492. 10.1097/01.fpc.0000166456.84905.a0, 15970796.
21. Evans JF. The cysteinyl leukotriene receptors. Prostaglandins Leukot Essent Fatty Acids 2003, 69(2-3):117-122. 10.1016/S0952-3278(03)00072-3, 12895594.
22. Brink C, Dahlen SE, Drazen J, Evans JF, Hay DW, Nicosia S, Serhan CN, Shimizu T, Yokomizo T. International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol Rev 2003, 55(1):195-227. 10.1124/pr.55.1.8, 12615958.
23. Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y. Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. J Biol Chem 2004, 279(44):46129-46134. 10.1074/jbc.M407057200, 15328359.
24. Corrigan C, Mallett K, Ying S, Roberts D, Parikh A, Scadding G, Lee T. Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis. J Allergy Clin Immunol 2005, 115(2):316-322. 10.1016/j.jaci.2004.10.051, 15696087.
25. Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989, 17(15):6419. 10.1093/nar/17.15.6419, 318318, 2771659.