Cough-reflex sensitivity to inhaled capsaicin in COPD associated with increased exacerbation frequency

Respirology

Volumn 14, Issue 8, 2009, Pages 1151-1155

  Terada, Kunihiko ^a   Muro, Shigeo ^a   Ohara, Tadashi ^a   Haruna, Akane ^a   Marumo, Satoshi ^a   Kudo, Megumi ^a   Ogawa, Emiko ^a   Hoshino, Yuma ^a   Hirai, Toyohiro ^a   Niimi, Akio ^a   Mishima, Michiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

C reactive protein; Chronic obstructive pulmonary disease; Cough reflex sensitivity; Exacerbation; Inflammation

Indexed keywords

C REACTIVE PROTEIN; CAPSAICIN;

AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; COUGHING; DISEASE EXACERBATION; DRUG SENSITIVITY; FEMALE; HUMAN; HYPERSENSITIVITY; MALE; MORBIDITY; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY;

AGED; C-REACTIVE PROTEIN; CAPSAICIN; CAUSALITY; COUGH; FORCED EXPIRATORY VOLUME; HUMANS; MALE; OUTCOME ASSESSMENT (HEALTH CARE); PREVALENCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REFLEX; REGRESSION ANALYSIS; RESPIRATORY HYPERSENSITIVITY; SENSORY SYSTEM AGENTS; SEVERITY OF ILLNESS INDEX; VITAL CAPACITY;

EID: 70350482647     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2009.01620.x     Document Type: Article

References (29)

1. National Heart, Lung, and Blood Institute World Health Organization Workshop Report. Global initiative for chronic obstructive lung disease (GOLD): global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NIH Publication No. 2701. Bethesda, 2003.
2. Donaldson GC, Seemungal TAR, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002 57 : 847 852.
3. Seemungal TAR, Donaldson GC, Paul EA, Bestall JC, Jeffries DJ et al. Effect of exacerbation on quality of life in subjects with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1998 157 : 1418 1422.
4. Ashton CM, Ferguson JA, Goldacre MJ. In-patient workload in medical specialities. 2. Profiles of individual diagnoses from linked statistics. Q. J. Med. 1995 88 : 661 672.
5. Rennard S, Decramer M, Calverley PMA, Pride NB, Soriano JB et al. Impact of COPD in North America and Europe in 2000: subjects' perspective of Confronting COPD International Survey. Eur. Respir. J. 2002 20 : 799 805.
6. Burgel PR, Nesme-Meyer P, Chanez P, Caillaud D, Carre P et al. Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects. Chest 2009 135 : 975 982.
7. 1 decline and chronic obstructive pulmonary disease morbidity Copenhagen city heart study group. Am. J. Respir. Crit. Care Med. 1996 153 : 1530 1535.
8. Anthonisen NR, Manfreda J, Warren CPW, Hershfield ES, Harding GKM et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann. Intern. Med. 1987 106 : 196 204.
9. Doherty MJ, Mister R, Pearson MG, Calverley PMA. Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax 2000 55 : 643 649.
10. Prudon B, Birring SS, Vara DD, Hall AP, Thompson JP et al. Cough and glottic-stop reflex sensitivity in health and disease. Chest 2005 127 : 550 557.
11. Choudry NB, Fuller RW. Sensitivity of the cough reflex in subjects with chronic cough. Eur. Respir. J. 1992 5 : 296 300.
12. Barnes PJ, Chowdhury B, Kharitonov SA, Magnussen H, Page CP et al. Pulmonary biomarkers in COPD. Am. J. Respir. Crit. Care Med. 2006 174 : 6 14.
13. Terada K, Muro S, Sato S, Ohara T, Haruna A et al. Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation. Thorax 2008 63 : 951 955.
14. Japanese Respiratory Society. Guideline of respiratory function tests-spirometry, flow-volume curve, diffusion capacity of the lung. Nihon Kokyuki Gakkai Zasshi 2004 42 (Suppl. 1 1 56.
15. Niimi A, Matsumoto H, Ueda T, Takemura M, Suzuki K et al. Impaired cough reflex in subjects with recurrent pneumonia. Thorax 2003 58 : 152 153.
16. Lee LY, Pisarri TE. Afferent properties and reflex functions of bronchopulmonary C-fibers. Respir. Physiol. 2001 125 : 47 65.
17. Coleridge JC, Coleridge HM. Afferent vagal C fiber innervation of the lungs and airways and its functional significance. Rev. Physiol. Biochem. Pharmacol. 1984 99 : 1 110.
18. Wedricha JA, Seemungal TAR. COPD exacerbations: defining their cause and prevention. Lancet 2007 370 : 786 796.
19. Bhowmik A, Seemungal TAR, Sapsford RJ, Wedzicha JA. Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000 55 : 114 120.
20. Tumkaya M, Atis S, Ozge C, Delialioglu N, Polat G et al. Relationship between airway colonization, inflammation, and exacerbation frequency in COPD. Respir. Med. 2007 101 : 729 737.
21. Takemura M, Matsumoto H, Niimi A, Ueda T, Matsuoka H et al. High sensitivity C-reactive protein in asthma. Eur. Respir. J. 2006 27 : 908 912.
22. Ariff AA, Delclos GL, Colmer-Hamood J. Association between asthma, asthma symptoms, and C-reactive protein in US adults: data from the national health and nutrition examination survey, 1999-2002. Respirology 2007 12 : 675 682.
23. Dahl M, Vestbo J, Lange P, Bojesen SE, Tybjarg-Hansen A et al. C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2007 175 : 250 255. (Pubitemid 46203128)
24. Ridker PM. High-sensitivity C-reactive protein potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation 2001 103 : 1813 1818.
25. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. JAMA 1999 282 : 2131 2135.
26. Yudkin JS, Stehouwer CD, Emeis JJ, Coppack CW. C-reactive protein in healthy subjects: association with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler. Thromb. Vasc. Biol. 1999 19 : 972 978.
27. Fujimura M, Myou S, Matsuda M, Amemiya T, Kamio Y et al. Cough receptor sensitivity to capsaicin and tartaric acid in subjects with Mycoplasma pneumonia. Lung 1998 176 : 281 288.
28. Brightling CE, Ward R, Wardlaw AJ, Pavord ID. Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis. Eur. Respir. J. 2000 15 : 682 686.
29. Chang AB, Phelan PD, Robertson CF, Roberts RG, Sawyer SM. Relation between measurements of cough severity. Arch. Dis. Child. 2003 88 : 57 60.