Tackling agitated delirium - the tip of the iceberg

Critical Care

Volumn 13, Issue 3, 2009, Pages

  Page, Valerie J ^a  

^a WATFORD GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE; HALOPERIDOL; HYPNOTIC SEDATIVE AGENT; NEUROLEPTIC AGENT;

AGITATION; ARTIFICIAL VENTILATION; CLINICAL TRIAL; DELIRIUM; DRUG EFFICACY; EXTUBATION; HUMAN; INTENSIVE CARE; LENGTH OF STAY; MORTALITY; NOTE; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; SEDATION; UNITED KINGDOM; RESTLESSNESS;

ANTIPSYCHOTIC AGENTS; DELIRIUM; DEXMEDETOMIDINE; HALOPERIDOL; HUMANS; HYPNOTICS AND SEDATIVES; PSYCHOMOTOR AGITATION; RESPIRATION, ARTIFICIAL;

EID: 70350448709     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc7912     Document Type: Note

References (14)

1. Reade MC, O'Sullivan K, Bates S, Goldsmith D, Ainslie WR, Bellomo R. Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial. Crit Care 2009, 13:R75. 19454032, 10.1186/cc7890.
2. Lonergan E, Luxenberg J, Areosa Sastre A, Wyller TB. Benzodiazepines for delirium. Cochrane Database Syst Rev 2009, (1):CD006379.
3. Baddigam K, Russo P, Russo J, Tobias JD. Dexmedetomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients. J Intensive Care Med 2005, 20:118-123. 10.1177/0885066604273481, 15855224.
4. Arpino PA, Kalafatas K, Thompson BT. Feasibility of dexmedetomidine in facilitating extubation in the intensive care unit. J Clin Pharm Ther 2008, 33:25-30.
5. MacLaren R, Forrest LK, Kiser TH. Adjunctive dexmedetomidine therapy in the ICU: a retrospective assessment of the impact on sedative and analgesic requirements, levels of sedation and analgesia and ventilatory and hemodynamic parameters. Pharmacotherapy 2007, 27:351-359. 10.1592/phco.27.3.351, 17316147.
6. Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE, Inouye SK, Bernard GR, Dittus RS. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004, 291:1753-1762. 10.1001/jama.291.14.1753, 15082703.
7. Spronk PE, Riekerk B, Hofhuis J, Rommes JH. Occurrence of delirium is severely underestimated in the ICU during daily care. Intensive Care Med 2009,
8. Page VJ, Navarange S, Gama S, McAuley D. Routine delirium monitoring in a UK critical care unit. Crit Care 2009, 13:R16. 2688133, 19203391, 10.1186/cc7714.
9. Jackson J, Gordon S, Hart R, Hopkins RO, Ely EW. The association between delirium and cognitive decline: a review of the empirical literature. Neuropsychol Rev 2004, 14:87-98. 15264710, 10.1023/B:NERV.0000028080.39602.17.
10. Milbrandt EB, Kersten A, Kong L, Weissfeld L, Clermont G, Fink M, Angus D. Haloperidol is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med 2005, 33:226-229. 10.1097/01.CCM.0000150743.16005.9A, 15644675.
11. Wang P, Schneeweiss S, Avorn J, Fischer M, Mogun H, Solomon D, Brookhart M. Risk of death in elderly users of conventional vs. atypical antipsychotic medications. N Engl J Med 2005, 353:2335-2341. 10.1056/NEJMoa052827, 16319382.
12. Siddiqi N, Stockdale R, Britton AM, Holmes J. Interventions for preventing delirium in hospitalised patients. Cochrane Database Syst Rev 2007, (2):CD005563.
13. Lonergan E, Britton AM, Luxenberg J. Antipsychotics for delirium. Cochrane Database Syst Rev 2007, (2):CD005594.
14. ICU delirium - diagnosing, treating and preventing delirium in ICU patients. , http://www.icudelirium.co.uk