Effects of organophosphate phenyl saligenin phosphate and polyether carboxylic ionophore lasalocid on motor nerve conduction velocity, neuropathy target esterase enzyme activity, and clinical ataxia in chickens

Toxicology Mechanisms and Methods

Volumn 19, Issue 5, 2009, Pages 351-355

  Kart, Asim ^a   Bilgili, Ali ^b  

^a KAFKAS UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

Lasalocid; Motor nerve conduction velocity (MNCV); Neuropathy; Neuropathy target esterase (NTE); Organophosphate

Indexed keywords

CALCIUM ION; ESTERASE; IONOPHORE; LASALOCID; ORGANOPHOSPHATE; PHENYLSALIGENIN PHOSPHATE; POLYETHER; SALIGENIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN; CHEMICAL STRUCTURE; CHICKEN; CONTROLLED STUDY; ENZYME ACTIVATION; MOTOR NERVE CONDUCTION; NEUROPATHY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; SPINAL CORD;

ANIMALS; ATAXIA; CARBOXYLIC ESTER HYDROLASES; CHICKENS; INSECTICIDES; IONOPHORES; MALE; MOTOR NEURONS; NEURAL CONDUCTION; ORGANOPHOSPHORUS COMPOUNDS;

ANIMALIA; BOS; GALLUS GALLUS;

EID: 70350443018     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510903030403     Document Type: Article

References (34)

1. Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV. 2004. Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration. Proc Natl Acad Sci USA 101:5075-5080.
2. Bouldin TW, Cavanagh JB. 1979. Organophosphorous neuropathy 2. Finestructural study of the early stages of axonal degeneration. Am J Pathol 94:253-270.
3. Carlson K, Ehrich M. 2004. Organophophorus compound-induced delayed neurotoxicity in White Leghorn hens assessed by Fluoro-Jade. Int J Toxicol 23:259-266.
4. El-Fawal HA, Jortner BS, Ehrich M. 1989. Effect of verapamil on organophosphorus-induced delayed neuropathy in hens. Toxicol Appl Pharmacol 97:500-511.
5. El-Fawal HA, McCain MC. 2008. Antibodies to neural proteins in organophosphorus-induced delayed neuropathy (OPIDN) and its amelioration. Neurotoxicol Teratol 30:161-166.
6. Espino L, Suarez ML, Mino N, Goicoa A, Fidalgo LE, Santamarina G. 2003. Suspected lasalocid poisining in three dogs. Vet Hum Toxicol 45:241-242.
7. Glynn P. 2006. A mechanism for organophosphate-induced delayed neuropathy. Toxicol Lett 162:94-97.
8. Gregory DG, Vanhooser SL,d Stair EL. 1995. Light and electron-microscopic lesions in peripheral-nerves of broiler-chickens due to roxarsone and lasalocid toxicoses. Avian Dis 39:408-416.
9. Johnson MK. 1977. Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential. Arch Toxicol 37:113-115.
10. Jortner BS. 2000. Mechanisms of toxic injury in the peripheral nervous system: neuropathologic considerations. Toxicol Pathol 28:54-69.
11. Jortner BS, Ehrich M. 1987. Neuropathological effects of phenyl saligenin phosphate in chickens. Neurotoxicology 8:98-108.
12. Kart A. 2005. Neuropathic aspect of organophosphate toxicity: A review. J Anim Vet Adv 4:723-725.
13. Kart A, Bilgili A. 2008. Ionophore antibiotics: Toxicity, mode of action and neurotoxic aspect of carboxylic ionophores. J Anim Vet Adv 7:748-751.
14. Lidsky TI, Manetto C, Ehrich M. 1990. Nerve-conduction studies in chickens given phenyl saligenin phosphate and corticosterone. J Toxicol Environ Health 29:65-75.
15. Lopachin RM, Lapadula DM, Abou-Donia MB. 1988. Organophosphate intoxication alters distribution of elements in chicken peripheral nerve. Neurosci Abstr 14:775.
16. Lopachin RM, Saubermann AJ. 1990. Disruption of cellular-elements and water in neurotoxicity-studies using electron-probe x-ray-microanalysis. Toxicol Appl Pharmacol 106:355-374.
17. Lotti M. 1992. The pathogenesis of organophosphate polyneuropathy. Toxicology 21:465-487.
18. Luttrell WE, Olajos EJ, Pleban PA. 1993. Change in hen sciatic nerve calcium after single oral dose of tri-o-toluil phosphate. Environ Res 60:290-294.
19. Makhaeva G, Malygin V. 2005. Organophosphate induced delayed neurotoxicity. In: Monov A, Dishovsky C (Eds.), Medical aspects of chemical and biological terrorism. Sofia: Publ. House of the Union of Scientists in Bulgaria; pp. 271-302.
20. Massicotte C, Barber DS, Jortner BS, Ehrich M. 2001. Nerve conduction and ATP concentrations in sciatic-tibial and medial plantar nerves of hens given phenyl saligenin phosphate. Neurotoxicology 22:91-98.
21. Massicotte C, Inzana KD, Ehrich M, Jortner BS. 1999. Neuropathologic effects of phenylmethylsulfonyl fluoride (PMSF)-induced promotion and protection in organophosphorus ester-induced delayed neuropathy (OPIDN) in hens. Neurotoxicology 20:749-759.
22. Parascandola J. 1995. The Public Health Service and Jamaica ginger paralysis in the 1930s. Public Health Rep 110:361-363.
23. Pellin M, Vicedo JL, Vilanova E. 1987. Sensitivity to Tri-ortho-cresylphosphate neurotoxicity on normal-hexane exposed hens as a model of simultaneous hexacarbon solvent and organophosphorus occupational intoxication. Arch Toxicol 59:311-318.
24. Pellin MC, Vilanova E, Barril J. 1988. Low non-neuropathic tri-ortho-cresyl phosphate (TOCP) doses inhibit neuropathy target esterase near the neuropathic threshold in normal-hexane pretreated hens. Toxicology 49:99-105.
25. Piao F, Yamauch T, Ma N. 2003. The effect of Calcicol as calcium tonic on delayed neurotoxicity induced by organophosphorus compounds. Toxicol Lett 143:65-71.
26. Pope CN. 1999. Organophosphorus pesticides: Do they all have the same mechanism of toxicity? J Toxicol Environ Health B Crit Rev 2:161-181.
27. Pope CN, Padilla S. 1990. Potentiation of organophosphorus-induced delayed neurotoxicity by phenylmethylsulfonyl fluoride. J Toxicol Environ Health 31:261-273.
28. Pope CN, Tanaka D, Padilla S. 1993. The role of neurotoxic esterase (nte) in the prevention and potentiation of organophosphorus-induced delayed neurotoxicity (OPIDN). Chem Biol Interact 87:395-406.
29. Robertson DG, Schwab BW, Sills RD, Richardson RJ, Anderson RJ. 1987. Electrophysiologic changes following treatment with organophosphorusinduced delayed neuropathy-producing agents in the adult hen. Toxicol Appl Pharmacol 87:420-429.
30. Roder JD. 1996. Lasalocid induced neuropathy, PhD thesis. The Graduate School, Oklahoma State University, Stillwater, Oklahoma.
31. Segev G, Baneth G, Levitin B, Shlosberg A, Aroch I. 2004. Accidental poisoning of 17 dogs with lasalocid. Vet Rec 155:174-176.
32. Shell L, Jortner BS, Ehrich M. 1988. Assessment of organophosphorus- induced delayed neuropathy in chickens using needle electromyography. J Toxicol Environ Health 25:21-33. (Pubitemid 18246813)
33. Soliman SA, Linder R, Farmer J, Curley A. 1982. Species susceptibility to delayed toxic neuropathy in relation to in vivo inhibition of neurotoxic esterase by neurotoxic organo-phosphorus esters. J Toxicol Environ Health 9:189-197.
34. Wu YJ, Chang PA, Li M, Li YX, Li W. 2003. Effect of tri-o-cresyl phosphate and methamidophos on 45Ca uptake by brain synaptsomes in hens. Pestic Biochem Physiol 77:248-254.