Global or local QSAR: Is there a way out?

QSAR and Combinatorial Science

Volumn 28, Issue 8, 2009, Pages 850-855

  Feher, Miklos ^a,c   Ewing, Todd ^b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b PLEXXIKON INC   (United States)

^c NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

Consensus model; CYP450; Drug design; Fusion model; Global QSAR; Local QSAR; P450; Structure activity relationships

Indexed keywords

COMPUTATIONAL CHEMISTRY; MOLECULAR GRAPHICS;

CONSENSUS MODELS; DRUG DESIGN; FUSION MODEL; GLOBAL MODELS; GLOBAL QSAR; GLOBAL-LOCAL; LOCAL FUSION; LOCAL MODEL; LOCAL QSAR; STRUCTURE-ACTIVITY RELATIONSHIPS;

FORECASTING;

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4;

ACCURACY; ANALYTICAL ERROR; COMPUTER PREDICTION; CONFERENCE PAPER; INDUSTRIAL PRODUCTION; INTERMETHOD COMPARISON; MATHEMATICAL MODEL; PREDICTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REPRODUCIBILITY;

EID: 70350378922     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200860186     Document Type: Conference Paper

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