Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model

Lung Cancer

Volumn 66, Issue 2, 2009, Pages 162-168

  Yang, Chih Jen ^a   Wang, Chuan Sheng ^a   Hung, Jen Yu ^a   Huang, Hurng Wern ^b   Chia, Yi Chen ^c   Wang, Pei Hui ^d   Weng, Ching Feng ^e   Huang, Ming Shyan ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c TAJEN UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL DONG HWA UNIVERSITY   (Taiwan)

Author keywords

Animal model; Apoptosis; G2 M arrest; Lung cancer; PARP; Pyrogallol

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN TYROSINE PHOSPHATASE; PYROGALLOL; THREONINE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; TUMOR GROWTH; TUMOR XENOGRAFT; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE, TUMOR; CYTOTOXINS; DISEASE MODELS, ANIMAL; G2 PHASE; GROWTH INHIBITORS; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; PYROGALLOL;

EID: 70350348329     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.01.016     Document Type: Article

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