Differential regulation of the hydrogen-peroxide-induced inhibition of gap-junction intercellular communication by resveratrol and butylated hydroxyanisole

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 671, Issue 1-2, 2009, Pages 40-44

  Kim, Jong Hun ^a,b   Choi, Seung Hwan ^b   Kim, Jiyoung ^a,b   Lee, Bo Kyung ^b   Lee, Ki Won ^b   Lee, Hyong Joo ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

BHA; Cx43; ERK; GJIC; H2O2; Resveratrol

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); BUTYLATED HYDROXYANISOLE; CONNEXIN 43; GAP JUNCTION PROTEIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RESVERATROL;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CELL COMMUNICATION; CONTROLLED STUDY; DRUG STRUCTURE; GAP JUNCTION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; BUTYLATED HYDROXYANISOLE; CELL COMMUNICATION; CELL LINE; CONNEXIN 43; FREE RADICALS; GAP JUNCTIONS; HYDROGEN PEROXIDE; PHOSPHORYLATION; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION; STILBENES;

RATTUS;

EID: 70350343782     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.08.011     Document Type: Article

References (36)

1. Kumar N.M., and Gilula N.B. The gap junction communication channel. Cell 84 (1996) 381-388
2. Simon A.M., and Goodenough D.A. Diverse functions of vertebrate gap junctions. Trends Cell Biol. 8 (1998) 477-483
3. Bruzzone R., White T.W., and Paul D.L. Connections with connexins: the molecular basis of direct intercellular signaling. Eur. J. Biochem. 238 (1996) 1-27
4. Kang K.S., Yun J.W., Yoon B., Lim Y.K., and Lee Y.S. Preventive effect of germanium dioxide on the inhibition of gap junctional intercellular communication by TPA. Cancer Lett. 166 (2001) 147-153
5. Loewenstein W.R. Junctional intercellular communication: the cell-to-cell membrane channel. Physiol. Rev. 61 (1981) 829-913
6. Segretain D., and Falk M.M. Regulation of connexin biosynthesis, assembly, gap junction formation, and removal. Biochim. Biophys. Acta 1662 (2004) 3-21
7. Trosko J.E. Mechanisms of tumor promotion: possible role of inhibited intercellular communication. Eur. J. Cancer Clin. Oncol. 23 (1987) 599-601
8. Trosko J.E., and Ruch R.J. Cell-cell communication in carcinogenesis. Front. Biosci. 3 (1998) d208-d236
9. Kang K.S., Lee Y.S., Kim H.S., and Kim S.H. DI-(2-ethylhexyl) phthalate-induced cell proliferation is involved in the inhibition of gap junctional intercellular communication and blockage of apoptosis in mouse Sertoli cells. J. Toxicol. Environ. Health A 65 (2002) 447-459
10. Sai K., Kang K.S., Hirose A., Hasegawa R., Trosko J.E., and Inoue T. Inhibition of apoptosis by pentachlorophenol in v-myc-transfected rat liver epithelial cells: relation to down-regulation of gap junctional intercellular communication. Cancer Lett. (2001) 163-174
11. Upham B.L., Guzvic M., Scott J., Carbone J.M., Blaha L., Coe C., Li L.L., Rummel A.M., and Trosko J.E. Inhibition of gap junctional intercellular communication and activation of mitogen-activated protein kinase by tumor-promoting organic peroxides and protection by resveratrol. Nutr. Cancer 57 (2007) 38-47
12. Na H.K., Wilson M.R., Kang K.S., Chang C.C., Grunberger D., and Trosko J.E. Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line. Cancer Lett. 157 (2000) 31-38
13. Cho J.H., Cho S.D., Hu H., Kim S.H., Lee S.K., Lee Y.S., and Kang K.S. The roles of ERK1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against the inhibition of gap junctional intercellular communication by hydrogen peroxide. Carcinogenesis 23 (2002) 1163-1169
14. Lee K.M., Kwon J.Y., Lee K.W., and Lee H.J. Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway. Mutat. Res. 660 (2009) 51-56
15. Ruch R.J., Trosko J.E., and Madhukar B.V. Inhibition of connexin43 gap junctional intercellular communication by TPA requires ERK activation. J. Cell. Biochem. 83 (2001) 163-169
16. Huang R.P., Peng A., Golard A., Hossain M.Z., Huang R., Liu Y.G., and Boynton A.L. Hydrogen peroxide promotes transformation of rat liver non-neoplastic epithelial cells through activation of epidermal growth factor receptor. Mol. Carcinog. 30 (2001) 209-217
17. Upham B.L., Kang K.S., Cho H.Y., and Trosko J.E. Hydrogen peroxide inhibits gap junctional intercellular communication in glutathione sufficient but not glutathione deficient cells. Carcinogenesis 18 (1997) 37-42
18. Kang K.S., Kang B.C., Lee B.J., Che J.H., Li G.X., Trosko J.E., and Lee Y.S. Preventive effect of epicatechin and ginsenoside Rb(2) on the inhibition of gap junctional intercellular communication by TPA and H(2)O(2). Cancer Lett. 152 (2000) 97-106
19. Lee K.W., Lee H.J., Kang K.S., and Lee C.Y. Preventive effects of vitamin C on carcinogenesis. Lancet 359 (2002) 172
20. Kang K.S., Yun J.W., and Lee Y.S. Protective effect of l-carnosine against 12-O-tetradecanoylphorbol-13-acetate- or hydrogen peroxide-induced apoptosis on v-myc transformed rat liver epithelial cells. Cancer Lett. 178 (2002) 53-62
21. Crowell J.A., Korytko P.J., Morrissey R.L., Booth T.D., and Levine B.S. Resveratrol-associated renal toxicity. Toxicol. Sci. 82 (2004) 614-619
22. Lee K.W., Hur H.J., Lee H.J., and Lee C.Y. Antiproliferative effects of dietary phenolic substances and hydrogen peroxide. J. Agric. Food Chem. 53 (2005) 1990-1995
23. Brand-Williams W., Cuvelier M.E., and Berset C. Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci. Technol. 28 (1995) 25-30
24. Lee K.W., Kim Y.J., Lee H.J., and Lee C.Y. Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and red wine. J. Agric. Food Chem. 51 (2003) 7292-7295
25. van den Berg R., Haenen G.R.M.M., van den Berg H., and Bast A. Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chem. 66 (1999) 511-517
26. Cerutti P.A. Prooxidant states and tumor promotion. Science 227 (1985) 375-381
27. Trosko J.E., and Chang C.C. Modulation of cell-cell communication in the cause and chemoprevention/chemotherapy of cancer. Biofactors 12 (2000) 259-263
28. Huang R.P., Peng A., Hossain M.Z., Fan Y., Jagdale A., and Boynton A.L. Tumor promotion by hydrogen peroxide in rat liver epithelial cells. Carcinogenesis 20 (1999) 485-492
29. Lau A.F., Kanemitsu M.Y., Kurata W.E., Danesh S., and Boynton A.L. Epidermal growth factor disrupts gap-junctional communication and induces phosphorylation of connexin43 on serine. Mol. Biol. Cell 3 (1992) 865-874
30. Nielsen M., Ruch R.J., and Vang O. Resveratrol reverses tumor-promoter-induced inhibition of gap-junctional intercellular communication. Biochem. Biophys. Res. Commun. 275 (2000) 804-809
31. Lopez-Velez M., Martinez-Martinez F., and Del Valle-Ribes C. The study of phenolic compounds as natural antioxidants in wine. Crit. Rev. Food Sci. Nutr. 43 (2003) 233-244
32. Wattenberg L.W. Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by phenolic antioxidants and ethoxyquin. J. Natl. Cancer Inst. 48 (1972) 1425-1430
33. Williams G.M., Tanaka T., and Maeura Y. Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene. Carcinogenesis 7 (1986) 1043-1050
34. Ito N., Fukushima S., Hagiwara A., Shibata M., and Ogiso T. Carcinogenicity of butylated hydroxyanisole in F344 rats. J. Natl. Cancer Inst. 70 (1983) 343-352
35. Ito N., Hagiwara A., Shibata M., Ogiso T., and Fukushima S. Induction of squamous cell carcinoma in the forestomach of F344 rats treated with butylated hydroxyanisole. Gann 73 (1982) 332-334
36. Ito N., Hirose M., Fukushima S., Tsuda H., Shirai T., and Tatematsu M. Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis. Food Chem. Toxicol. 24 (1986) 1071-1082