Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells

Journal of Ethnopharmacology

Volumn 126, Issue 2, 2009, Pages 252-257

  Kim, Sangmin ^a   Kim, Sung Hoon ^a   Hur, Sung Mo ^a   Lee, Se Kyung ^a   Kim, Wan Wook ^a   Kim, Jee Soo ^a   Kim, Jung Han ^a   Choe, Jun Ho ^a   Nam, Seok Jin ^a   Lee, Jeong Eon ^a   Yang, Jung Hyun ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

COX 2; ERK; MMP 9; Silibinin; TPA

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; CELECOXIB; CYCLOOXYGENASE 2; GELATINASE B; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; SILIBININ;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; BREAST NEOPLASMS; BUTADIENES; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DOWN-REGULATION; HUMANS; MAP KINASE KINASE KINASES; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 9; MILK THISTLE; NITRILES; PHYTOTHERAPY; PROTEIN KINASE INHIBITORS; PYRAZOLES; SEEDS; SILYMARIN; SULFONAMIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 70350336245     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.08.032     Document Type: Article

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