FGF-2-loaded collagen scaffolds attract cells and blood vessels in rat oral mucosa

Journal of Oral Pathology and Medicine

Volumn 38, Issue 8, 2009, Pages 630-638

  Jansen, Richard G ^a   Van Kuppevelt, Toin H ^a   Daamen, Willeke F ^a   Kuijpers Jagtman, Anne M ^a   Von Den Hoff, Johannes W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

FGF 2; In vivo test; Oral; Scaffold; Wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; FIBROBLAST GROWTH FACTOR 2; RECOMBINANT FIBROBLAST GROWTH FACTOR; TISSUE SCAFFOLD;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; CELL DENSITY; CELL INFILTRATION; CLEFT PALATE; CONTROLLED STUDY; FOREIGN BODY REACTION; GIANT CELL; IMPLANTATION; INFLAMMATORY CELL; MALE; MAXILLA; MOUTH MUCOSA; MYOFIBROBLAST; NONHUMAN; PLASTIC SURGERY; PRIORITY JOURNAL; RAT; SCAR FORMATION; TISSUE ENGINEERING; WOUND CONTRACTION;

ANIMALS; CELL MOVEMENT; COLLAGEN TYPE I; DRUG DELIVERY SYSTEMS; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; GUIDED TISSUE REGENERATION; IMPLANTS, EXPERIMENTAL; LONGITUDINAL STUDIES; MALE; MOUTH MUCOSA; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PALATE; RATS; RATS, WISTAR; RECONSTRUCTIVE SURGICAL PROCEDURES; STATISTICS, NONPARAMETRIC; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 70350322430     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2009.00763.x     Document Type: Article

References (40)

1. Ross RB. Treatment variables affecting facial growth in complete unilateral cleft lip and palate. Cleft Palate J 1987; 24: 5-77.
2. Neligan PC, Gullane PJ, Gilbert RW. Functional reconstruction of the oral cavity. World J Surg 2003; 27: 856-862
3. Moharamzadeh K, Brook IM, Van Noort R, Scutt AM, Thornhill MH. Tissue-engineered oral mucosa: a review of the scientific literature. J Dent Res 2007; 86: 115-124
4. Ruszczak Z, Friess W. Collagen as a carrier for on-site delivery of antibacterial drugs. Adv Drug Del Rev 2003; 55: 1679-1698
5. Wallace DG, Rosenblatt J. Collagen gel systems for sustained delivery and tissue engineering. Adv Drug Del Rev 2003; 55: 1631-1649
6. Lee CH, Singla A, Lee Y. Biomedical applications of collagen. Int J Pharm 2001; 221: 1-22.
7. Ma L, Gao CY, Mao ZW, et al. Collagen / chitosan porous scaffolds with improved biostability for skin tissue engineering. Biomaterials 2003; 24: 4833-4841
8. Kurosaka D, Kato K, Nagamoto T, Negishi K. Growthfactors influence contractility and alpha-smooth muscle actin expression in bovine lens epithelial-cells. Invest Ophthalmol Vis Sci 1995; 36: 1701-1708
9. Pieper JS, Hafmans T, van Wachem PB, et al. Loading of collagen-heparan sulfate matrices with bFGF promotes angiogenesis and tissue generation in rats. J Biomed Mat Res 2002; 62: 185-194
10. Akasaka Y, Ono I, Tominaga A, et al. Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of alpha-smooth muscle actin, leading to reduction of wound contraction. Wound Rep Reg 2007; 15: 378-389
11. Spyrou GE, Naylor IL. The effect of basic fibroblast growth factor on scarring. Br J Plast Surg 2002; 55: 275-282
12. Ono I, Tateshita T, Inoue M. Effects of a collagen matrix containing basic fibroblast growth factor on wound contraction. J Biomed Mat Res 1999; 48: 621-630
13. Lee HG, Eun HC. Differences between fibroblasts cultured from oral mucosa and normal skin: implication to wound healing. J Dermatol Sci 1999; 21: 176-182
14. Stephens P, Davies KJ, Occleston N, et al. Skin and oral fibroblasts exhibit phenotypic differences in extracellular matrix reorganization and matrix metalloproteinase activity.Br J Dermatol 2001; 144: 229-237
15. Sciubba JJ, Waterhouse JP, Meyer J. Fine-structural comparison of healing of incisional wounds of mucosa and skin. J Oral Pathol Med 1978; 7: 214-226
16. Oda Y, Kagami H, Ueda M. Accelerating effects of basic fibroblast growth factor on wound healing of rat palatal mucosa. J Oral Maxillofac Surg 2004; 62: 73-80.
17. Hata Y, Kawanabe H, Hisanaga Y, Taniguchi K, Ishikawa H. Effects of basic fibroblast growth factor administration on vascular changes in wound healing of rat palates. Cleft Palate Craniofac J 2008; 45: 63-72.
18. Pieper JS, Oosterhof A, Dijkstra PJ, Veerkamp JH, van Kuppevelt TH. Preparation and characterization of porous crosslinked collagenous matrices containing bioavailable chondroitin sulphate. Biomaterials 1999; 20: 847-858
19. Damoiseaux JG, Dopp EA, Calame W, Chao D, MacPherson GG, Dijkstra CD. Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 1994; 83: 140-147
20. Zittermann SI, Issekutz AC. Basic fibroblast growth factor (bFGF, FGF-2) potentiates leukocyte recruitment to inflammation by enhancing endothelial adhesion molecule expression. Am J Pathol 2006; 168: 835-846
21. Whalen GF, Shing Y, Folkman J. The fate of intravenously administered bFGF and the effect of heparin. Growth Factors 1989; 1: 157-164
22. Lai PH, Chang Y, Chen SC, et al. Acellular biological tissues containing inherent glycosaminoglycans for loading basic fibroblast growth factor promote angiogenesis and tissue regeneration. Tissue Eng 2006; 12: 2499-2508
23. Sprugel KH, Mcpherson J, Clowes AW, Ross R. Growthfactors in subcutaneous chambers - cellular-responses in vivo. Fed Proc 1987; 46: 971.
24. Okada-Ban M, Thiery JP, Jouanneau J. Fibroblast growth factor-2. Int J Biochem Cell Biol 2000; 32: 263-267
25. Martin P, Hopkinson-Woolley J, McCluskey J. Growth factors and cutaneous wound repair. Prog Growth Factor Res 1992; 4: 25-44.
26. Hakkinen L, Uitto VJ, Larjava H. Cell biology of gingival wound healing. Periodontol 2000 2000; 24: 127-152
27. Szpaderska AM, Zuckerman JD, DiPietro LA. Differential injury responses in oral mucosal and cutaneous wounds. J Dent Res 2003; 82: 621-626
28. Nooh N, Graves DT. Healing is delayed in oral compared to dermal excisional wounds. J Periodontol 2003; 74: 242-246
29. Jansen RG, van Kuppevelt TH, Daamen WF, Kuijpers-Jagtman AM, Von den Hoff JW. Tissue reactions to collagen scaffolds in the oral mucosa and skin of rats: environmental and mechanical factors. Arch Oral Biol 2008; 53: 376-387
30. Loffek S, Zigrino P, Angel P, Anwald B, Krieg T, Mauch C. High invasive melanoma cells induce matrix metalloproteinase-1 synthesis in fibroblasts by interleukin-1 alpha and basic fibroblast growth factor-ediated mechanisms. J Invest Dermatol 2005; 124: 638-643
31. Ono I. The effects of basic fibroblast growth factor (bFGF) on the breaking strength of acute incisional wounds. J Dermatol Sci 2002; 29: 104-113
32. Hosseinkhani H, Hosseinkhani M, Khademhosseini A, Kobayashi H, Tabata Y. Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration. Biomaterials 2006; 27: 5836-5844
33. Yao C, Markowicz M, Pallua N, Noah EM, Steffens G. The effect of cross-linking of collagen matrices on their angiogenic capability. Biomaterials 2008; 29: 66-74.
34. Szpaderska AM, Walsh CG, Steinberg MJ, DiPietro LA. Distinct patterns of angiogenesis in oral and skin wounds. J Dent Res 2005; 84: 309-314
35. Nillesen STM, Geutjes PJ, Wismans R, Schalkwijk J, Daamen WF, van Kuppevelt TH. Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF. Biomaterials 2007; 28: 1123-1131
36. Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 2003; 200: 500-503
37. Funato N, Moriyama K, Shimokawa H, Kuroda T. Basic fibroblast growth factor induces apoptosis in myofibroblastic cells isolated from rat palatal mucosa. Biochem Biophys Res Commun 1997; 240: 21-26
38. van Beurden HE, Von den Hoff JW, Torensma R, Maltha JC, Kuijpers-Jagtman AM. Myofibroblasts in palatal wound healing: prospects for the reduction of wound contraction after cleft palate repair. J Dent Res 2005; 84: 871-880
39. Finesmith TH, Broadley KN, Davidson JM. Fibroblasts from wounds of different stages of repair vary in their ability to contract a collagen gel in response to growthfactors. J Cell Physiol 1990; 144: 99-107.
40. Westwood G, Dibling BC, Cuthbert-Heavens D, Burchill SA. Basic fibroblast growth factor (bFGF)-induced cell death is mediated through a caspase-dependent and p53-independent cell death receptor pathway. Oncogene 2002; 21: 809-824.