The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3′-phosphoadenosine 5′-phosphosulfate reveals a new ligand-binding mode

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 65, Issue 10, 2009, Pages 987-991

  Lee, Hyung Ho ^a   Yoon, Hye Jin ^a   Kang, Ji Yong ^a   Park, Ji Hyeon ^a   Kim, Do Jin ^a   Choi, Kwang Hyun ^b   Lee, Seung Kyu ^b   Song, Jinsu ^a   Kim, Hie Joon ^a   Suh, Se Won ^a  

^a Seoul National University   (South Korea)

^b ProMediTech   (South Korea)

Author keywords

3 phosphoadenosine 5 phosphosulfate; Coenzyme A biosynthetic pathway; Phosphopantetheine adenylyltransferases; Staphylococcus aureus

Indexed keywords

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; NUCLEOTIDYLTRANSFERASE; PANTETHEINE PHOSPHATE ADENYLYLTRANSFERASE; PANTETHEINE-PHOSPHATE ADENYLYLTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN QUATERNARY STRUCTURE; SEQUENCE ALIGNMENT; STAPHYLOCOCCUS AUREUS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDYLTRANSFERASES; PHOSPHOADENOSINE PHOSPHOSULFATE; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE ALIGNMENT; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 70350309480     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309109036616     Document Type: Article

References (20)

1. Aghajanian, S. & Worrall, D. M. (2002). Biochem. J. 365, 13-18.
2. Badger, J. et al. (2005). Proteins, 60, 787-796.
3. Bork, P., Holm, L., Koonin, E. V. & Sander, C. (1995). Proteins, 22, 259-266.
4. Brunger, A. T. (2007). Nature Protoc. 2, 2728-2733.
5. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T. & Warren, G. L. (1998). Acta Cryst. D54, 905-921.
6. Davis, I. W., Leaver-Fay, A., Chen, V. B., Block, J. N., Kapral, G. J., Wang, X., Murray, L. W., Arendall, W. B. III, Snoeyink, J., Richardson, J. S. & Richardson, D. C. (2007). Nucleic Acids Res. 35, W375-W383.
7. Geerlof, A., Lewendon, A. & Shaw, W. V. (1999). J. Biol. Chem. 274, 27105-27111.
8. Izard, T. (2002). J. Mol. Biol. 315, 487-495.
9. Izard, T. (2003). J. Bacteriol. 185, 4074-4080.
10. Izard, T. & Geerlof, A. (1999). EMBO J. 18, 2021-2030.
11. Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. (1991). Acta Cryst. A47, 110-119.
12. Klaassen, C. D. & Boles, J. W. (1997). FASEB J. 11, 404-418.
13. Leonardi, R., Zhang, Y.-M., Rock, C. O. & Jackowski, S. (2005). Prog. Lipid Res. 44, 125-153.
14. Morris, V. K. & Izard, T. (2004). Protein Sci. 13, 2547-2552.
15. Otwinowski, Z. & Minor, W. (1997). Methods Enzymol. 276, 307-326.
16. Robishaw, J. D. & Neely, J. R. (1985). Am. J. Physiol. 248, E1-E9.
17. Rossmann, M. G., Liljas, A., Brandé n, C. I. & Banaszak, L. J. (1975). The Enzymes, 3rd ed., edited by P. D. Boyer, Vol.XI, pp. 61-102. London: Academic Press.
18. Takahashi, H., Inagaki, E., Fujimoto, Y., Kuroishi, C., Nodake, Y., Nakamura, Y., Arisaka, F., Yutani, K., Kuramitsu, S., Yokoyama, S., Yamamoto, M., Miyano, M. & Tahirov, T. H. (2004). Acta Cryst. D60, 97-104.
19. Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F. & Higgins, D. G. (1997). Nucleic Acids Res. 25, 4876-4882.
20. Zhao, L., Allanson, N. M., Thomson, S. P., Maclean, J. K., Barker, J. J., Primrose,W. U., Tyler, P. D. & Lewendon, A. (2003). Eur. J. Med. Chem. 38, 345-349.