ADAM8 substrate specificity: Influence of pH on pre-processing and proteoglycan degradation

Archives of Biochemistry and Biophysics

Volumn 491, Issue 1-2, 2009, Pages 106-111

  Hall, Troii ^a   Pegg, Lyle E ^a   Pauley, Adele M ^a   Fischer, H David ^a   Tomasselli, Alfredo G ^a   Zack, Marc D ^a  

^a PFIZER INC   (United States)

Author keywords

ADAM8; Pre processing; Proteoglycan

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE 8; ADAM PROTEIN; BREVICAN; FIBRONECTIN; PROTEOGLYCAN; UNCLASSIFIED DRUG; VITRONECTIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL BOND; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ENZYME SPECIFICITY; PH; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING;

ADAM PROTEINS; BIOCATALYSIS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MEMBRANE PROTEINS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; SUBSTRATE SPECIFICITY;

EID: 70350304971     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2009.09.005     Document Type: Article

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